公开(公告)号：US20140295578A1

公开(公告)日：2014-10-02

申请号：US14301228

申请日：2014-06-10

Applicant: Access Medical Systems, LTD.

Inventor： Hong TAN ,  Ming Xia ,  Yushan Tan ,  Jun Chen ,  Erhua Cao ,  Genqian Ll ,  Robert F. Zuk

IPC: B01L3/00

CPC classification number: B01L3/52 ,  B01L3/502 ,  B01L3/527 ,  B01L2300/042 ,  B01L2300/045 ,  G01N33/54306 ,  G01N33/54353 ,  G01N33/54366 ,  G01N35/026 ,  G01N2035/0436

Abstract: This invention relates to a cartridge for an immunoassay test. The cartridge comprises (a) a probe well comprising a probe and a cap, the cap being in a closed position to enclose the probe in the probe well, wherein the probe has a bottom tip coated with analyte-binding molecules, (b) a sample well to receive a sample, (c) one or more reagent wells, (d) a plurality of wash wells each containing a first aqueous solution, and (e) a measurement well having a light transmissive bottom, the measurement well containing a second aqueous solution, wherein the openings of the sample well, reagent well, measurement well and wash wells are sealed. The present invention also relates to an apparatus for loading and releasing a probe. The apparatus comprises a push pin and a groove to load and transfer the probe to a plurality of locations, such as different wells in the above-mentioned cartridge, to conduct the immunoassay test.

Abstract translation: 本发明涉及用于免疫测定试验的药筒。 所述盒包括（a）包括探针和帽的探针孔，所述盖处于关闭位置以将所述探针包围在所述探针中，其中所述探针具有涂覆有分析物结合分子的底部末端，（b） 样品井以接收样品，（c）一个或多个试剂孔，（d）多个洗涤孔，每个洗涤孔含有第一水溶液，和（e）具有透光底部的测量孔，测量孔包含第二 水溶液，其中样品孔，试剂阱，测量井和洗涤井的开口被密封。 本发明还涉及一种用于装载和释放探针的装置。 该装置包括推针和凹槽，以将探针加载并转移到多个位置，例如上述药筒中的不同的孔，以进行免疫测定。