公开(公告)号：US20020082524A1

公开(公告)日：2002-06-27

申请号：US09748089

申请日：2000-12-21

Applicant: Advanced Cardiovascular Systems, Inc.

Inventor： David M. Anderson ,  Emmanuel C. Biagtan ,  Wayne E. Cornish ,  Sharon Y. Wong

IPC: A61B005/00

CPC classification number: A61M25/09 ,  A61M2025/09083 ,  A61M2025/09175

Abstract: A guidewire having a flexible coil with a tapered distal tip. Preferably, the flexible coil has a polymer coating at least at its tapered distal portion. The polymer coating may comprise polyurethanes or other suitable polymers. The guidewires of the invention provide desirable performance characteristics, particularly when used to cross relatively tight lesions such as chronic total occlusions.

Abstract translation: 导丝，其具有带锥形远端的柔性线圈。 优选地，柔性线圈至少在其锥形远端部分具有聚合物涂层。 聚合物涂层可以包括聚氨酯或其它合适的聚合物。 本发明的导丝线提供期望的性能特征，特别是当用于交叉相对紧密的损伤（例如慢性完全闭塞）时。

公开(公告)号：US20010003146A1

公开(公告)日：2001-06-07

申请号：US09772803

申请日：2001-01-29

Applicant: Advanced Cardiovascular Systems, Inc.

Inventor： Marc Mehrzad Jalisi ,  Emmanuel C. Biagtan

IPC: A61B005/00 ,  A61M025/00

CPC classification number: A61M25/09016 ,  A61L29/085 ,  A61L29/103 ,  A61L31/082 ,  A61L31/10 ,  A61L2420/08 ,  A61M25/0045 ,  A61M25/09 ,  Y10T428/2942

Abstract: An intraluminal device having an adhesive primer coat formed of a carbonaceous material and a lubricious top coat of a hydrophilic polymeric material. The invention also comprises the methods of making such intraluminal devices. The primer coat of the invention may comprise pure carbon, or a carbon based material such as a polymer. Preferably, the primer coat has a thickness of about 0.1 to about 2 nullm. In a presently preferred embodiment, the primer coat is applied using chemical vapor deposition (CVD), but in certain embodiments, physical vapor deposition (PVD) may be suitable. The deposited primer coat forms an effective substrate for adhesion of the hydrophilic polymer top coat.