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1.发明申请Efficient synthetic routes for the preparation of rhinovirus protease inhibitors and key intermediates 失效用于制备鼻病毒蛋白酶抑制剂和关键中间体的高效合成路线公开(公告)号：US20020133020A1
公开(公告)日：2002-09-19
申请号：US09984555
申请日：2001-10-30
发明人： Qingping Tian , Naresh K. Nayyar , Srinivasan Babu , Junhua Tao , Terence Jarold Moran , Raymond Dagnino JR. , Lennert J. Mitchell JR. , Travis Paul Remarchuk , Michael Joseph Melnick , Steven Lee Bender
IPC分类号： C07D413/02
CPC分类号： B01J19/2435 , B01J19/2475 , B01J2219/00033 , B01J2219/00099 , B01J2219/00103 , B01J2219/00159 , B01J2219/00162 , B01J2219/00177 , C07B2200/07 , C07C69/732 , C07C229/34 , C07C271/22 , C07C303/28 , C07D207/26 , C07D261/18 , C07D413/12 , C07C309/65
摘要： Efficient synthetic routes for the preparation of rhinovirus protease inhibitors of formula I, as well as key intermediates useful in those synthetic routes. These compounds of formula I, as well as pharmaceutical compositions that contain these compounds, are suitable for treating patients or hosts infected with one or more picornaviruses. 1
摘要翻译： 用于制备式I的鼻病毒蛋白酶抑制剂的高效合成路线，以及在那些合成路线中有用的关键中间体。 这些式I化合物以及含有这些化合物的药物组合物适用于治疗患有一种或多种微小核糖核酸病毒感染的患者或宿主。
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2.发明申请Efficient methods for the preparation of rhinovirus protease inhibitors, key intermediates and a continuous membrane reactor useful for preparing the same 审中-公开用于制备鼻病毒蛋白酶抑制剂，关键中间体和用于制备鼻病毒蛋白酶抑制剂的连续膜反应器的有效方法公开(公告)号：US20030064429A1
公开(公告)日：2003-04-03
申请号：US10201944
申请日：2002-07-25
发明人： Junhua Tao , Srinivasan Babu , Raymond Dagnino JR. , Qingping Tian , Travis Paul Remarchuk , Kevin Scott McGee , Naresh K. Nayyar , Terence Jarold Moran
IPC分类号： C12P033/02 , C12N009/48 , C12N009/50
CPC分类号： C07D207/26 , B01J19/2435 , B01J19/2475 , B01J2219/00033 , B01J2219/00099 , B01J2219/00103 , B01J2219/00159 , B01J2219/00162 , B01J2219/00177 , C07B2200/07 , C07C69/732 , C07C229/34 , C07C271/22 , C07C303/28 , C07D261/18 , C07D413/12 , C07C309/65
摘要： Efficient synthetic routes for the preparation of rhinovirus protease inhibitors of formula I, key intermediates useful in those synthetic routes, as well as a continuous membrane reactor useful for those synthetic routes. These compounds of formula I, as well as pharmaceutical compositions that contain these compounds, are suitable for treating patients or hosts infected with one or more picornaviruses. 1
摘要翻译： 用于制备式I的鼻病毒蛋白酶抑制剂的有效合成路线，可用于那些合成途径的关键中间体，以及用于那些合成途径的连续膜反应器。 这些式I化合物以及含有这些化合物的药物组合物适用于治疗患有一种或多种微小核糖核酸病毒感染的患者或宿主。
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