公开(公告)号：US20140113378A1

公开(公告)日：2014-04-24

申请号：US14140152

申请日：2013-12-24

Applicant: AJINOMOTO CO., INC.

Inventor： Mitsuo TAKAHASHI ,  Hiroshi YAMAMOTO ,  Fumihiko TAKATSUKI ,  Toshihiko ANDO ,  Minoru YAMAKADO

IPC: G06F19/18

CPC classification number: G06F19/18 ,  G01N33/6812 ,  G01N2800/085

Abstract: A method of evaluating fatty liver related disease includes (I) an obtaining step of obtaining amino acid concentration data on a concentration value of an amino acid in blood collected from a subject to be evaluated and (II) a concentration value criterion evaluating step of evaluating a state of a fatty liver related disease including at least one of fatty liver, NAFLD, and NASH in the subject, based on the amino acid concentration data of the subject obtained at the obtaining step.

Abstract translation: 评价脂肪肝相关疾病的方法包括：（I）获得从待评价对象收集的血液中的氨基酸的浓度值的氨基酸浓度数据的获取步骤，（II）评价对象的浓度值判定步骤 基于在获得步骤中获得的受试者的氨基酸浓度数据，包括受试者中的脂肪肝，NAFLD和NASH中的至少一种的脂肪肝相关疾病的状态。

公开(公告)号：US20210287802A1

公开(公告)日：2021-09-16

申请号：US17307644

申请日：2021-05-04

Applicant: Ajinomoto Co., Inc.

Inventor： Nobukazu ONO ,  Atsuko SHINHARA ,  Takahiko MURAMATSU ,  Shinya KIKUCHI ,  Hiroshi YAMAMOTO ,  Koichi SHIRAISHI ,  Kazuhiro KATAYAMA ,  Nobuyasu FUKUTAKE ,  Masahiko HIGASHIYAMA ,  Shinichi OHKAWA ,  Makoto UENO ,  Yohei MIYAGI ,  Naoyuki OKAMOTO

IPC: G16H50/20 ,  G01N33/574 ,  G01N33/68 ,  G16B99/00 ,  G16B20/00

Abstract: A method of evaluating pancreatic cancer includes (I) an obtaining step of obtaining amino acid concentration data on a concentration value of an amino acid in blood collected from a subject to be evaluated, and (II) an evaluating step of evaluating a state of pancreatic cancer in the subject by calculating a value of a formula using the amino acid concentration data of the subject obtained at the obtaining step and the formula previously established for evaluating the state of pancreatic cancer, including an explanatory variable to be substituted with the concentration value of the amino acid. The amino acid concentration data includes the concentration values of at least two amino acids of Asn, His, Thr, Ala, Cit, Arg, Tyr, Val, Met, Lys, Trp, Gly, Pro, Orn, Ile, Leu, Phe, Ser, and Gln, and the formula includes at least two explanatory variables to be substituted with the concentration values of at least two amino acids of Asn, His, Thr, Ala, Cit, Arg, Tyr, Val, Met, Lys, Trp, Gly, Pro, Orn, Ile, Leu, Phe, Ser, and Gln.

公开(公告)号：US20160253454A1

公开(公告)日：2016-09-01

申请号：US14988986

申请日：2016-01-06

Applicant: Ajinomoto Co., Inc.

Inventor： Takahiko MURAMATSU ,  Yutaka IHATA ,  Akira IMAIZUMI ,  Hiroshi YAMAMOTO ,  Etsuko MIYAGI ,  Fumiki HIRAHARA

IPC: G06F19/24 ,  G01N33/574

CPC classification number: G16B40/00 ,  G01N33/57411 ,  G01N33/57442 ,  G01N33/57449

Abstract: According to the method of evaluating female genital cancer of the present invention, amino acid concentration data on concentration values of amino acids in blood collected from a subject to be evaluated is measured, and the state of female genital cancer including at least one of cervical cancer, endometrial cancer, and ovarian cancer in the subject is evaluated based on the concentration value of at least one of Thr, Ser, Asn, Gln, Pro, Gly, Ala, Cit, Val, Met, Ile, Leu, Tyr, Phe, His, Trp, Orn, Lys, and Arg contained in the measured amino acid concentration data of the subject.

Abstract translation: 根据本发明的女性生殖器癌的评价方法，测定从被评价对象收集的血液中的氨基酸的浓度值的氨基酸浓度数据，包括宫颈癌中的至少一种的女性生殖器癌的状态 基于Thr，Ser，Asn，Gln，Pro，Gly，Ala，Cit，Val，Met，Ile，Leu，Tyr，Phe中的至少一种的浓度值来评估受试者的子宫内膜癌和卵巢癌， His，Trp，Orn，Lys和Arg包含在受试者的测量的氨基酸浓度数据中。