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14 条记录 (耗时 0.022 秒)

    Anthelmintic composition and the use thereof
    2.
    发明授权
    Anthelmintic composition and the use thereof 失效
    驱虫组合物及其用途

    公开(公告)号：US4468390A

    公开(公告)日：1984-08-28

    申请号：US350641

    申请日：1982-02-22

    申请人： Noritoshi Kitano

    发明人： Noritoshi Kitano

    IPC分类号： A61K31/35 ,  A61K31/365 ,  A61K31/40 ,  A61K31/415 ,  A61K31/47 ,  A61K31/495 ,  A61K31/60 ,  A61K31/70 ,  A61P33/00 ,  A61P33/10 ,  A61K31/625 ,  A61K31/335

    CPC分类号： A61K31/60 ,  A61K31/415 ,  A61K31/47 ,  A61K31/495

    摘要： The combined administration of:(a) one or more macrolide anthelmintic agents selected from the group consisting of B-41 series antibiotics, C-076 series antibiotics and 22,23-dihydro C-076 derivatives; and(b) one or more anthelmintic agents selected from the group consisting of benzimidazole, salicylamide and isoquinoline compounds,has been bound to exhibit enhanced anthelmintic activity as compared with the additive use of the individual compounds.

    摘要翻译： 联合施用：（a）一种或多种选自B-41系列抗生素，C-076系列抗生素和22,23-二氢C-076衍生物的大环内酯类驱虫剂; 和（b）与单独化合物的添加剂使用相比，一种或多种选自苯并咪唑，水杨酰胺和异喹啉化合物的驱肠虫剂已经结合显示出增强的驱肠虫活性。

    Pyridine derivatives and their use as anticoccidial agents
    5.
    发明授权
    Pyridine derivatives and their use as anticoccidial agents 失效
    吡啶衍生物及其用作抗焦虑剂

    公开(公告)号：US4098893A

    公开(公告)日：1978-07-04

    申请号：US816215

    申请日：1977-07-15

    申请人： Yasuhiro Morisawa ,  Mitsuru Kataoka ,  Noritoshi Kitano ,  Toshiaki Matsuzawa

    发明人： Yasuhiro Morisawa ,  Mitsuru Kataoka ,  Noritoshi Kitano ,  Toshiaki Matsuzawa

    IPC分类号： C07D213/81 ,  C07D213/82 ,  C07D213/85 ,  A61K31/44 ,  C07D213/56

    CPC分类号： C07D213/81 ,  C07D213/82 ,  C07D213/85

    摘要： Pyridine derivatives having the formula ##STR1## wherein R.sub.1 is an alkyl group having 1 to 3 carbon atoms; R.sub.2 is hydrogen atom or an alkyl group having 1 to 3 carbon atoms; R.sub.3 is hydrogen atom, an alkyl group having 1 to 4 carbon atoms, an alkenyl group having 3 or 4 carbon atoms, an alkyl group having 1 or 2 carbon atoms and hydroxy as a substituent, an alkanoyl group having 1 to 18 carbon atoms, an alkenoyl group having 3 to 11 carbon atoms, an aromatic acyl group having 6 or 10 carbon atoms in the aromatic ring and optionally alkyl, alkoxy, acetylamino, cyano or halogen as a substituent, a heterocyclic acyl group, an alkylcarbamoyl group having 1 to 4 carbon atoms in the alkyl moiety, an allylcarbamoyl group or hydroxy group; n is an integer of 0 to 2 inclusive; and, when n is 2, R.sub.1 's may be the same or different; provided that when R.sub.2 is said alkyl group having 1 to 3 carbon atoms, R.sub.3 is said alkyl group having 1 to 4 carbon atoms.They are highly effective in the treatment of coccidiosis.

    Compositions and methods for the treatment of coccidiosis
    6.
    发明授权
    Compositions and methods for the treatment of coccidiosis 失效
    用于治疗结肠炎的组合物和方法

    公开(公告)号：US4053608A

    公开(公告)日：1977-10-11

    申请号：US602574

    申请日：1975-08-07

    申请人： Yasuhiro Morisawa ,  Mitsuru Kataoka ,  Noritoshi Kitano ,  Toshiaki Matsuzawa

    发明人： Yasuhiro Morisawa ,  Mitsuru Kataoka ,  Noritoshi Kitano ,  Toshiaki Matsuzawa

    IPC分类号： C07D213/61 ,  C07D213/81 ,  C07D333/38 ,  C07D409/12 ,  A61K31/455 ,  A61K31/44

    CPC分类号： C07D213/81

    摘要： Anticoccidial compositions which comprise as active ingredient pyridine derivatives having the formula ##STR1## wherein R.sub.1 is hydrogen atom, a halomethyl group or methyl group;R.sub.2 is hydrogen atom or an alkyl group of 1-3 carbon atoms;R.sub.3 is hydrogen atom, an alkyl group of 1-3 carbon atoms, allyl group, an alkyl group having 2 or 3 carbon atoms and alkoxy of 1 or 2 carbon atoms as a substituent, an alkyl group having 1-3 carbon atoms and hydroxy as a substituent, an alkanoyl group of 1-18 carbon atoms, a haloacetyl group, an alkenoyl group of 3-11 carbon atoms, an aromatic acyl group, a heterocyclic acyl group, an N-alkylcarbamoyl group of 1-4 carbon atoms in the alkyl moiety or hydroxy group;Provided that when R.sub.2 is said alkyl group of 1-3 carbon atoms, R.sub.3 is said alkyl group of 1-3 carbon atoms and inorganic acid addition salts thereof.

    Substitute pyridinol-containing compositions and methods for the treatment of coccidiosis
    9.
    发明授权
    Substitute pyridinol-containing compositions and methods for the treatment of coccidiosis 失效
    替代含吡啶酚的组合物和治疗球虫病的方法

    公开(公告)号：US3935311A

    公开(公告)日：1976-01-27

    申请号：US509720

    申请日：1974-09-26

    申请人： Yasuhiro Morisawa ,  Mitsuru Kataoka ,  Taiichiro Watanabe ,  Noritoshi Kitano ,  Toshiaki Matsuzawa

    发明人： Yasuhiro Morisawa ,  Mitsuru Kataoka ,  Taiichiro Watanabe ,  Noritoshi Kitano ,  Toshiaki Matsuzawa

    IPC分类号： A23K1/16 ,  C07F9/58 ,  A61K31/675

    CPC分类号： C07F9/58 ,  A23K20/116 ,  A23K20/132 ,  A23K20/137

    摘要： A composition which comprises a pyridinol derivative of the formula ##SPC1##Intimately dispersed in an inert edible carrier, wherein R.sub.1 and R.sub.2 may be the same or different and each represents a hydrogen atom; a lower alkyl group, an aralkyl group, an aliphatic, an aromatic or a heterocyclic acyl group; an alkoxycarbonyl group; an aralkoxycarbonyl group; an aryloxycarbonyl group; a N-substituted carbonyl group; a N-substituted thiocarbonyl group; a phosphono group; or a salt thereof.The composition is a preventive and curative anticoccidial agent for poultry and domestic animals. Particularly, it shows a significant activity against chronic coccidiosis caused by Eimeria acervulina.The composition is less toxic for animals, besides it has an advantage that it is also effective for coccidiosis caused by coccidia resistant to the known anticoccidial agents.

    摘要翻译： 一种组合物，其包含在任何可食用载体中分散的式的吡啶酚衍生物，其中R 1和R 2可以相同或不同，并且各自表示氢原子; 低级烷基，芳烷基，脂族，芳族或杂环酰基; 烷氧基羰基; 芳烷氧基羰基; 芳氧基羰基; N-取代的羰基; N-取代的硫代羰基; 膦酰基; 或其盐。