公开(公告)号：US11938058B2

公开(公告)日：2024-03-26

申请号：US16061671

申请日：2016-12-15

Applicant: Alcon Inc.

Inventor： Andrew T. Schieber ,  Charles L. Euteneuer ,  David T. Van Meter ,  Kenneth M. Galt

IPC: A61F9/007 ,  A61B3/16 ,  A61M5/00 ,  A61M25/00

CPC classification number: A61F9/00781 ,  A61B3/16 ,  A61M5/00 ,  A61M25/00

Abstract: An illustrative method for reducing intraocular pressure in a patient may comprise deploying an ocular implant adapted to reside at least partially in a portion of Schlemm's canal of an eye and administering a therapeutic agent comprising a Rho kinase (ROCK) inhibitor to the patient. The ocular implant may be configured to lower the intraocular pressure from an initial to a second pressure within a first range and the therapeutic agent may lower an intraocular pressure to a third pressure within a second range, the third pressure lower than the second pressure.

公开(公告)号：US20230165711A1

公开(公告)日：2023-06-01

申请号：US18159818

申请日：2023-01-26

Applicant: Alcon Inc.

Inventor： John Wardle ,  Andrew Thomas Schieber ,  Kenneth M. Galt

IPC: A61F9/00 ,  A61F9/007

CPC classification number: A61F9/0017 ,  A61F9/0026 ,  A61F9/00781

Abstract: An ocular implant is provided. In some embodiments, the ocular implant includes a body that is curved about a longitudinal central axis and a distal body portion that defines a longitudinal channel including a channel opening. The implant is sized and configured such that the ocular implant assumes an orientation in which the channel opening is adjacent a major side of Schlemm’s canal when the ocular implant is disposed in Schlemm’s canal. Methods for delivering ocular implants into Schlemm’s canal are also provided. Some methods include covering openings in the ocular implant, advancing the implant into Schlemm’s canal while at least some of the openings are covered, and uncovering the openings while the distal portion of the implant is disposed in Schlemm’s canal.

公开(公告)号：US11596546B2

公开(公告)日：2023-03-07

申请号：US16520139

申请日：2019-07-23

Applicant: ALCON INC.

Inventor： John Wardle ,  Andrew T. Schieber ,  Kenneth M. Galt

IPC: A61F9/00 ,  A61F9/007

Abstract: An ocular implant is provided. In some embodiments, the ocular implant includes a body that is curved about a longitudinal central axis and a distal body portion that defines a longitudinal channel including a channel opening. The implant is sized and configured such that the ocular implant assumes an orientation in which the channel opening is adjacent a major side of Schlemm's canal when the ocular implant is disposed in Schlemm's canal. Methods for delivering ocular implants into Schlemm's canal are also provided. Some methods include covering openings in the ocular implant, advancing the implant into Schlemm's canal while at least some of the openings are covered, and uncovering the openings while the distal portion of the implant is disposed in Schlemm's canal.