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公开(公告)号:US20110059112A1
公开(公告)日:2011-03-10
申请号:US12888312
申请日:2010-09-22
申请人: Alexander W. Koch , Scott Stawicki , Yan Wu , Richard Carano , Franklin V. Peale, JR. , Ryan J. Watts
发明人: Alexander W. Koch , Scott Stawicki , Yan Wu , Richard Carano , Franklin V. Peale, JR. , Ryan J. Watts
IPC分类号: A61K39/395 , C07K16/18 , A61P35/00
CPC分类号: C07K16/2803 , A61K2039/505 , C07K16/30 , C07K2317/55 , C07K2317/565 , C07K2317/76 , C07K2317/77 , C07K2317/92
摘要: The invention provides anti-Robo4 antibodies, and compositions comprising the antibodies and methods of using these antibodies, including diagnostic and therapeutic methods.
摘要翻译: 本发明提供抗Robo4抗体,以及包含抗体的组合物和使用这些抗体的方法,包括诊断和治疗方法。
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公开(公告)号:US07834154B2
公开(公告)日:2010-11-16
申请号:US12028124
申请日:2008-02-08
申请人: Alexander W. Koch , Scott Stawicki , Yan Wu , Richard Carano , Franklin V. Peale, Jr. , Ryan J. Watts
发明人: Alexander W. Koch , Scott Stawicki , Yan Wu , Richard Carano , Franklin V. Peale, Jr. , Ryan J. Watts
CPC分类号: C07K16/2803 , A61K2039/505 , C07K16/30 , C07K2317/55 , C07K2317/565 , C07K2317/76 , C07K2317/77 , C07K2317/92
摘要: The invention provides anti-Robo4 antibodies, and compositions comprising the antibodies and methods of using these antibodies, including diagnostic and therapeutic methods.
摘要翻译: 本发明提供抗Robo4抗体,以及包含抗体的组合物和使用这些抗体的方法,包括诊断和治疗方法。
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公开(公告)号:US20110059013A1
公开(公告)日:2011-03-10
申请号:US12888316
申请日:2010-09-22
申请人: Alexander W. Koch , Scott Stawicki , Yan Wu , Richard Carano , Franklin V. Peale, JR. , Ryan J. Watts
发明人: Alexander W. Koch , Scott Stawicki , Yan Wu , Richard Carano , Franklin V. Peale, JR. , Ryan J. Watts
CPC分类号: C07K16/2803 , A61K2039/505 , C07K16/30 , C07K2317/55 , C07K2317/565 , C07K2317/76 , C07K2317/77 , C07K2317/92
摘要: The invention provides anti-Robo4 antibodies, and compositions comprising the antibodies and methods of using these antibodies, including diagnostic and therapeutic methods.
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公开(公告)号:US20080247951A1
公开(公告)日:2008-10-09
申请号:US12028124
申请日:2008-02-08
申请人: Alexander W. Koch , Scott Stawicki , Yan Wu , Richard Carano , Franklin V. Peale , Ryan J. Watts
发明人: Alexander W. Koch , Scott Stawicki , Yan Wu , Richard Carano , Franklin V. Peale , Ryan J. Watts
IPC分类号: A61K49/00 , C07K16/00 , A61K39/395
CPC分类号: C07K16/2803 , A61K2039/505 , C07K16/30 , C07K2317/55 , C07K2317/565 , C07K2317/76 , C07K2317/77 , C07K2317/92
摘要: The invention provides anti-Robo4 antibodies, and compositions comprising the antibodies and methods of using these antibodies, including diagnostic and therapeutic methods.
摘要翻译: 本发明提供抗Robo4抗体,以及包含抗体的组合物和使用这些抗体的方法,包括诊断和治疗方法。
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公开(公告)号:US20100221262A1
公开(公告)日:2010-09-02
申请号:US12622345
申请日:2009-11-19
申请人: Alexander W. Koch , Ryan J. Watts , Yan Wu , Anil D. Bagri
发明人: Alexander W. Koch , Ryan J. Watts , Yan Wu , Anil D. Bagri
IPC分类号: A61K39/395 , C07K16/00 , C12N15/13 , C12N15/63 , C12N1/00 , C12N5/00 , C12P21/00 , A61K31/7052 , G01N33/53 , A61P35/00 , A61P9/10
CPC分类号: C07K16/2803 , A61K2039/505 , C07K2317/21 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92
摘要: The invention provides anti-Unc5B antibodies, compositions and kits comprising the antibodies and methods of making and using the antibodies. The present invention also relates to use of anti-Unc5B antibodies to modulate angiogenesis and to treat or prevent disorders associated with abnormal angiogenesis.
摘要翻译: 本发明提供抗Unc5B抗体,包含抗体的组合物和试剂盒以及制备和使用抗体的方法。 本发明还涉及抗Unc5B抗体调节血管生成并治疗或预防与异常血管生成相关的病症的用途。
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公开(公告)号:US20120148599A1
公开(公告)日:2012-06-14
申请号:US13292633
申请日:2011-11-09
申请人: Jasvinder Atwal , Yongmei Chen , Cecilia Pui Chi Chiu , Robert A. Lazarus , Weiru Wang , Ryan J. Watts , Yan Wu , Yingnan Zhang
发明人: Jasvinder Atwal , Yongmei Chen , Cecilia Pui Chi Chiu , Robert A. Lazarus , Weiru Wang , Ryan J. Watts , Yan Wu , Yingnan Zhang
IPC分类号: A61K39/395 , C12N15/13 , C12N5/10 , C12P21/02 , G01N33/573 , C12N9/50 , C07K16/40 , C07K19/00
CPC分类号: C07K16/40 , A61K39/3955 , A61K47/6871 , A61K2039/505 , C07K2317/51 , C07K2317/515 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C12P21/005 , G01N33/573
摘要: The invention provides antibodies to specific neural proteins and methods of using the same.
摘要翻译: 本发明提供了针对特定神经蛋白的抗体及其使用方法。
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公开(公告)号:US08772457B2
公开(公告)日:2014-07-08
申请号:US13292633
申请日:2011-11-09
申请人: Jasvinder Atwal , Yongmei Chen , Cecilia Pui Chi Chiu , Robert A. Lazarus , Weiru Wang , Ryan J. Watts , Yan Wu , Yingnan Zhang
发明人: Jasvinder Atwal , Yongmei Chen , Cecilia Pui Chi Chiu , Robert A. Lazarus , Weiru Wang , Ryan J. Watts , Yan Wu , Yingnan Zhang
IPC分类号: C07K16/18 , C12P21/08 , A61K39/395
CPC分类号: C07K16/40 , A61K39/3955 , A61K47/6871 , A61K2039/505 , C07K2317/51 , C07K2317/515 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C12P21/005 , G01N33/573
摘要: The invention provides antibodies to specific neural proteins and methods of using the same.
摘要翻译: 本发明提供了针对特定神经蛋白的抗体及其使用方法。
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公开(公告)号:US20120245330A1
公开(公告)日:2012-09-27
申请号:US13489299
申请日:2012-06-05
申请人: Ryan J. Watts , Yan Wu
发明人: Ryan J. Watts , Yan Wu
IPC分类号: C07K16/28
CPC分类号: C07K16/2863 , A61K31/404 , A61K31/502 , A61K31/506 , A61K31/517 , A61K31/661 , A61K31/69 , A61K39/3955 , A61K39/39558 , A61K45/06 , C07K16/22 , C07K16/3023 , C07K2317/31 , C07K2317/565 , C07K2317/76 , C07K2317/92
摘要: Novel anti-NRP1 antibodies and variants thereof having unique structural and functional characteristics are disclosed. Also provided are uses of the antibodies in research, diagnostic and therapeutic applications.
摘要翻译: 公开了具有独特结构和功能特征的新型NRP1抗体及其变体。 还提供了抗体在研究,诊断和治疗应用中的用途。
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公开(公告)号:US07994286B2
公开(公告)日:2011-08-09
申请号:US12107544
申请日:2008-04-22
申请人: Ryan J. Watts , Yan Wu
发明人: Ryan J. Watts , Yan Wu
CPC分类号: C07K16/2863 , A61K31/404 , A61K31/502 , A61K31/506 , A61K31/517 , A61K31/661 , A61K31/69 , A61K39/3955 , A61K39/39558 , A61K45/06 , C07K16/22 , C07K16/3023 , C07K2317/31 , C07K2317/565 , C07K2317/76 , C07K2317/92
摘要: Novel anti-NRP1 antibodies and variants thereof having unique structural and functional characteristics are disclosed. Also provided are uses of the antibodies in research, diagnostic and therapeutic applications.
摘要翻译: 公开了具有独特结构和功能特征的新型NRP1抗体及其变体。 还提供了抗体在研究,诊断和治疗应用中的用途。
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公开(公告)号:US20110256146A1
公开(公告)日:2011-10-20
申请号:US13173890
申请日:2011-06-30
申请人: Ryan J. Watts , Yan Wu
发明人: Ryan J. Watts , Yan Wu
IPC分类号: A61K39/395 , A61P35/04 , C07K16/22
CPC分类号: C07K16/2863 , A61K31/404 , A61K31/502 , A61K31/506 , A61K31/517 , A61K31/661 , A61K31/69 , A61K39/3955 , A61K39/39558 , A61K45/06 , C07K16/22 , C07K16/3023 , C07K2317/31 , C07K2317/565 , C07K2317/76 , C07K2317/92
摘要: Novel anti-NRP1 antibodies and variants thereof having unique structural and functional characteristics are disclosed. Also provided are uses of the antibodies in research, diagnostic and therapeutic applications.
摘要翻译: 公开了具有独特结构和功能特征的新型NRP1抗体及其变体。 还提供了抗体在研究,诊断和治疗应用中的用途。
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