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公开(公告)号：US5361201A
公开(公告)日：1994-11-01
申请号：US963908
申请日：1992-10-19
申请人： Allen Jost , Jennifer Nelson , Krishna Gopinathan , Craig Smith
发明人： Allen Jost , Jennifer Nelson , Krishna Gopinathan , Craig Smith
摘要： An automated real estate appraisal system (100) and method generates estimates of real estate value using a predictive model such as a neural network (908). The predictive model (908) generates these estimates based on learned relationships among variables describing individual property characteristics (905) as well as general neighborhood characteristics at various levels of geographic specificity (906). The system (100) may also output reason codes indicating relative contributions (1009) of various variables to a particular result, and may generate reports (701) describing property valuations, market trend analyses, property conformity information, and recommendations regarding loans based on risk related to a property.
摘要翻译： 自动化房地产估价系统（100）和方法使用诸如神经网络（908）的预测模型来生成房地产价值的估计。 预测模型（908）基于描述个体特征的变量（905）之间的学习关系以及各种地理特异性的一般邻域特征（906）来生成这些估计。 系统（100）还可以输出指示各种变量对特定结果的相对贡献（1009）的原因代码，并且可以生成描述属性评估，市场趋势分析，财产合规信息以及关于基于风险的贷款的建议的报告（701） 与物业相关。
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2.发明授权Aptamers to tissue factor pathway inhibitor and their use as bleeding disorder therapeutics 有权适应组织因子途径抑制剂及其作为出血障碍治疗的用途公开(公告)号：US08598327B2
公开(公告)日：2013-12-03
申请号：US13026165
申请日：2011-02-11
申请人： Robert Schaub , Kathleen McGinness , Jennifer Nelson , Ryan Genga , Emily Waters , Jeffrey Kurz , John Diener
发明人： Robert Schaub , Kathleen McGinness , Jennifer Nelson , Ryan Genga , Emily Waters , Jeffrey Kurz , John Diener
CPC分类号： A61K38/1709
摘要： The invention relates generally to the field of nucleic acids and more particularly to aptamers that bind to TFPI, which are useful as therapeutics in and diagnostics of bleeding disorders and/or other diseases or disorders in which TFPI has been implicated. In addition, the TFPI aptamers may be used before, during and/or after medical procedures to reduce complications or side effects thereof. The invention further relates to materials and methods for the administration of aptamers that bind to TFPI.
摘要翻译： 本发明一般涉及核酸领域，更具体地涉及与TFPI结合的适体，其可用作出血性疾病和/或其中涉及TFPI的其它疾病或病症的治疗剂和诊断。 此外，TFPI适体可以在医疗过程之前，期间和/或之后使用以减少其并发症或副作用。 本发明还涉及用于施用与TFPI结合的适体的材料和方法。
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3.发明申请APTAMERS TO TISSUE FACTOR PATHWAY INHIBITOR AND THEIR USE AS BLEEDING DISORDER THERAPEUTICS 有权APTAMERS组织因子途径抑制剂及其作为BLEEDING DISORDER THERAPEUTICS使用公开(公告)号：US20110281938A1
公开(公告)日：2011-11-17
申请号：US13026165
申请日：2011-02-11
申请人： Robert Schaub , Kathleen McGinness , Jennifer Nelson , Ryan Genga , Emily Waters , Jeffrey Kurz , John Diener
发明人： Robert Schaub , Kathleen McGinness , Jennifer Nelson , Ryan Genga , Emily Waters , Jeffrey Kurz , John Diener
CPC分类号： A61K38/1709
摘要： The invention relates generally to the field of nucleic acids and more particularly to aptamers that bind to TFPI, which are useful as therapeutics in and diagnostics of bleeding disorders and/or other diseases or disorders in which TFPI has been implicated. In addition, the TFPI aptamers may be used before, during and/or after medical procedures to reduce complications or side effects thereof. The invention further relates to materials and methods for the administration of aptamers that bind to TFPI.
摘要翻译： 本发明一般涉及核酸领域，更具体地涉及与TFPI结合的适体，其可用作出血性疾病和/或其中涉及TFPI的其它疾病或病症的治疗剂和诊断。 此外，TFPI适体可以在医疗过程之前，期间和/或之后使用以减少其并发症或副作用。 本发明还涉及用于施用与TFPI结合的适体的材料和方法。
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4.发明申请APTAMERS TO TISSUE FACTOR PATHWAY INHIBITOR AND THEIR USE AS BLEEDING DISORDER THEREAPEUTICS 有权APTAMERS对组织因子途径抑制剂及其作为BLEEDING DISORDER THEREAPEUTECS使用公开(公告)号：US20120190834A1
公开(公告)日：2012-07-26
申请号：US13288634
申请日：2011-11-03
申请人： Robert Schaub , Kathleen McGinness , Jennifer Nelson , Ryan Genga , Emily Waters , Jeffrey Kurz , John Diener
发明人： Robert Schaub , Kathleen McGinness , Jennifer Nelson , Ryan Genga , Emily Waters , Jeffrey Kurz , John Diener
IPC分类号： C07H21/04
CPC分类号： A61K38/1709
摘要： The invention relates generally to the field of nucleic acids and more particularly to aptamers that bind to TFPI, which are useful as therapeutics in and diagnostics of bleeding disorders and/or other diseases or disorders in which TFPI has been implicated. In addition, the TFPI aptamers may be used before, during and/or after medical procedures to reduce complications or side effects thereof. The invention further relates to materials and methods for the administration of aptamers that bind to TFPI.
摘要翻译： 本发明一般涉及核酸领域，更具体地涉及与TFPI结合的适体，其可用作出血性疾病和/或其中涉及TFPI的其它疾病或病症的治疗剂和诊断。 此外，TFPI适体可以在医疗过程之前，期间和/或之后使用以减少其并发症或副作用。 本发明还涉及用于施用与TFPI结合的适体的材料和方法。
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5.发明申请Hydrogen storage material based on platelets and/or a multilayered core/shell structure 失效基于血小板和/或多层核/壳结构的储氢材料公开(公告)号：US20050074612A1
公开(公告)日：2005-04-07
申请号：US10800033
申请日：2004-03-15
申请人： Peter Eklund , Terumi Furuta , Hajime Goto , Yoshiya Fujiwara , James Adair , Jennifer Nelson , Kishore Srinivasan
发明人： Peter Eklund , Terumi Furuta , Hajime Goto , Yoshiya Fujiwara , James Adair , Jennifer Nelson , Kishore Srinivasan
CPC分类号： B82Y30/00 , B22F1/0018 , B22F9/24 , B22F2001/0033 , B22F2999/00 , C01B3/0078 , C01B3/0084 , Y02E60/324 , Y10T428/12014 , Y10T428/12181 , Y10T428/2982 , Y10T428/2991 , B22F1/0003
摘要： A hydrogen storage material includes a nano size material that can be formed in a multi-layered core/shell structure and/or in a nanotabular (or platelet) form.
摘要翻译： 储氢材料包括可以以多层核/壳结构和/或纳米尺寸（或血小板）形式形成的纳米尺寸的材料。
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6.发明授权Aptamers to tissue factor pathway inhibitor and their use as bleeding disorder therapeutics 有权适应组织因子途径抑制剂及其作为出血障碍治疗的用途公开(公告)号：US08252913B2
公开(公告)日：2012-08-28
申请号：US12858369
申请日：2010-08-17
申请人： Robert G. Schaub , Kathleen McGinness , Jennifer Nelson , Ryan Genga , Emily Waters , Jeffrey C. Kurz , John L. Diener
发明人： Robert G. Schaub , Kathleen McGinness , Jennifer Nelson , Ryan Genga , Emily Waters , Jeffrey C. Kurz , John L. Diener
CPC分类号： A61K38/1709 , C12N15/115 , C12N2310/16
摘要： The invention relates generally to the field of nucleic acids and more particularly to aptamers that bind to TFPI, which are useful as therapeutics in and diagnostics of bleeding disorders and/or other diseases or disorders in which TFPI has been implicated. In addition, the TFPI aptamers may be used before, during and/or after medical procedures to reduce complications or side effects thereof. The invention further relates to materials and methods for the administration of aptamers that bind to TFPI.
摘要翻译： 本发明一般涉及核酸领域，更具体地涉及与TFPI结合的适体，其可用作出血性疾病和/或其中涉及TFPI的其它疾病或病症的治疗剂和诊断。 此外，TFPI适体可以在医疗过程之前，期间和/或之后使用以减少其并发症或副作用。 本发明还涉及用于施用与TFPI结合的适体的材料和方法。
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7.发明授权Aptamers to tissue factor pathway inhibitor and their use as bleeding disorder thereapeutics 有权适应组织因子途径抑制剂及其作为出血性疾病的治疗药物公开(公告)号：US08461318B2
公开(公告)日：2013-06-11
申请号：US13288634
申请日：2011-11-03
申请人： Robert Schaub , Kathleen McGinness , Jennifer Nelson , Ryan Genga , Emily Waters , Jeffrey Kurz , John Diener
发明人： Robert Schaub , Kathleen McGinness , Jennifer Nelson , Ryan Genga , Emily Waters , Jeffrey Kurz , John Diener
CPC分类号： A61K38/1709
摘要： The invention relates generally to the field of nucleic acids and more particularly to aptamers that bind to TFPI, which are useful as therapeutics in and diagnostics of bleeding disorders and/or other diseases or disorders in which TFPI has been implicated. In addition, the TFPI aptamers may be used before, during and/or after medical procedures to reduce complications or side effects thereof. The invention further relates to materials and methods for the administration of aptamers that bind to TFPI.
摘要翻译： 本发明一般涉及核酸领域，更具体地涉及与TFPI结合的适体，其可用作出血性疾病和/或其中涉及TFPI的其它疾病或病症的治疗剂和诊断。 此外，TFPI适体可以在医疗过程之前，期间和/或之后使用以减少其并发症或副作用。 本发明还涉及用于施用与TFPI结合的适体的材料和方法。
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8.发明申请Aptamers to Tissue Factor Pathway Inhibitor and Their Use as Bleeding Disorder Therapeutics 有权组织因子途径抑制剂的适应症及其作为出血障碍治疗的用途公开(公告)号：US20110098345A1
公开(公告)日：2011-04-28
申请号：US12858369
申请日：2010-08-17
申请人： Robert G. Schaub , Kathleen McGinness , Jennifer Nelson , Ryan Genga , Emily Waters , Jeffrey C. Kurz , John L. Diener
发明人： Robert G. Schaub , Kathleen McGinness , Jennifer Nelson , Ryan Genga , Emily Waters , Jeffrey C. Kurz , John L. Diener
IPC分类号： A61K31/7088 , C07H21/02 , C07H21/04 , A61P7/00
CPC分类号： A61K38/1709 , C12N15/115 , C12N2310/16
摘要： The invention relates generally to the field of nucleic acids and more particularly to aptamers that bind to TFPI, which are useful as therapeutics in and diagnostics of bleeding disorders and/or other diseases or disorders in which TFPI has been implicated. In addition, the TFPI aptamers may be used before, during and/or after medical procedures to reduce complications or side effects thereof. The invention further relates to materials and methods for the administration of aptamers that bind to TFPI.
摘要翻译： 本发明一般涉及核酸领域，更具体地涉及与TFPI结合的适体，其可用作出血性疾病和/或其中涉及TFPI的其它疾病或病症的治疗剂和诊断。 此外，TFPI适体可以在医疗过程之前，期间和/或之后使用以减少其并发症或副作用。 本发明还涉及用于施用与TFPI结合的适体的材料和方法。
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