公开(公告)号：US12185750B2

公开(公告)日：2025-01-07

申请号：US15172468

申请日：2016-06-03

Applicant: Altria Client Services LLC

Inventor： Gerd Kobal ,  Douglas R. Oliveri ,  Peter Reeh ,  Tatjana Kichko

IPC: A24B15/38 ,  A24B13/00 ,  A24B15/16 ,  A24B15/167 ,  A24B15/28 ,  A24F23/02 ,  A24F40/10 ,  A61K9/00 ,  A61K9/50 ,  A61K31/465 ,  A61M11/04 ,  H05B3/00

Abstract: A smokeless tobacco product or medicinal nicotine product including nicotine and acyl nornicotine. Preferably, the acyl nornicotine is selected from the group consisting of N-Pentanoylnornicotine, N-Hexanoylnornicotine, N-Heptanolynornicotine, N-Octanoylnornicotine, N-Nonanoylnornicotine, N-Decanoylnornicotine, N-Undecanoylnornicotine, and N-Dedecanoylnornicotine. Also disclosed are methods of making such products.

公开(公告)号：US09538782B2

公开(公告)日：2017-01-10

申请号：US14206734

申请日：2014-03-12

Applicant: Altria Client Services LLC

Inventor： Gerd Kobal ,  Douglas Oliveri ,  Peter Reeh ,  Maria Gogova

IPC: A24B15/30 ,  A24B15/40 ,  A24B15/34 ,  A24B15/32 ,  A24B13/00 ,  A24B15/24

CPC classification number: A24B15/30 ,  A24B13/00 ,  A24B15/24 ,  A24B15/301 ,  A24B15/303 ,  A24B15/32 ,  A24B15/34 ,  A24B15/403

Abstract: Combinations of compounds utilized to minimize the sensory irritating character of non-smokeable tobacco products or non-smokeable products containing tobacco extracts or materials derived from tobacco.

Abstract translation: 化合物的组合用于最小化不可抽烟的烟草制品或含烟草提取物或来自烟草的材料的不可抽烟产品的感觉刺激性。

公开(公告)号：US10335378B2

公开(公告)日：2019-07-02

申请号：US14208619

申请日：2014-03-13

Applicant: Altria Client Services LLC

Inventor： Gerd Kobal ,  Justin Heynekamp ,  Peter Reeh ,  Munmaya K. Mishra ,  Tetyana Kichko

IPC: A61P25/34 ,  A61K31/125 ,  A61K31/045 ,  A61K45/06 ,  A61K31/22 ,  A61K9/00

Abstract: Pharmaceutical compositions and methods of use therefor for reducing the desire to engage in smoking are disclosed. More specifically, the pharmaceutical composition utilizes an active ingredient to reduce the side effects of smoking cessation and to limit the molecular feedback caused by nicotine-mediated activation of acetylcholine receptors.

公开(公告)号：US20160353795A1

公开(公告)日：2016-12-08

申请号：US15172468

申请日：2016-06-03

Applicant: Altria Client Services LLC

Inventor： Gerd Kobal ,  Douglas R. Oliveri ,  Peter Reeh ,  Tatjana Kichko

IPC: A24B15/38 ,  A24F47/00 ,  A24B13/00 ,  A24B15/16 ,  A61M11/04 ,  A61K31/465 ,  A61K9/50 ,  A61K9/00 ,  H05B3/00 ,  A24F23/02 ,  A24B15/28

CPC classification number: A24B15/385 ,  A24B13/00 ,  A24B15/16 ,  A24B15/167 ,  A24B15/282 ,  A24F23/02 ,  A24F47/008 ,  A61K9/007 ,  A61K9/50 ,  A61K31/4439 ,  A61K31/465 ,  A61M11/041 ,  H05B3/0014 ,  A61K2300/00

Abstract: A smokeless tobacco product or medicinal nicotine product including nicotine and acyl nornicotine. Preferably, the acyl nornicotine is selected from the group consisting of N-Pentanoylnornicotine, N-Hexanoylnornicotine, N-Heptanolynornicotine, N-Octanoylnornicotine, N-Nonanoylnornicotine, N-Decanoylnornicotine, N-Undecanoylnornicotine, and N-Dedecanoylnornicotine. Also disclosed are methods of making such products.

Abstract translation: 无烟烟草产品或药用尼古丁产品，包括尼古丁和酰基降烟碱。 优选地，酰基下降烟碱选自N-戊酰基降烟碱，N-己酰基降烟碱，N-庚酰多尼尼古丁，N-辛酰基降烟碱，N-壬酰基降烟碱，N-癸酰基降烟碱，N-十一烷基降烟碱，以及N-十一烷基降烟碱。 还公开了制造这种产品的方法。