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公开(公告)号：US07217530B2
公开(公告)日：2007-05-15
申请号：US11148945
申请日：2005-06-09
申请人： Aly Moussa , Anthony William Coleman , Patrick Shahgaldian , Eric Da Silva , Ambroise Martin , Adina Nicoleta Lazar , Edwige Leclere , Marilyne Dupin , Herve Perron
发明人： Aly Moussa , Anthony William Coleman , Patrick Shahgaldian , Eric Da Silva , Ambroise Martin , Adina Nicoleta Lazar , Edwige Leclere , Marilyne Dupin , Herve Perron
IPC分类号： G01N33/53 , G01N33/551 , G01N33/547 , C12Q1/37 , C07K1/04
CPC分类号： G01N33/6896 , G01N2800/2828 , Y10S435/961 , Y10S436/823 , Y10S530/807
摘要： A process for detecting the forms of the prion pathogens responsible for subacute, transmissible, spongiform encephalopathies, including a macrocyclic adjuvant ligand (AML), free or bound to a support, that is added to a biological sample capable of containing PrPsc, the resulting suspension then being reacted with an anti-PrPsc antibody, and the presence of PrP is then detected.
摘要翻译： 检测负责亚急性，可传染，海绵状脑病的朊病毒病原体的形式的方法，其包括游离或结合载体的大环佐剂配体（AML），其被添加到能够含有PrP sc 所得悬浮液然后与抗PrP超抗原反应，然后检测PrP的存在。
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2.发明申请公开(公告)号：US20100292272A1
公开(公告)日：2010-11-18
申请号：US12377065
申请日：2007-08-10
IPC分类号： A61K9/10 , A61K47/10 , A61K31/337 , A61K31/454 , A61P35/04 , A61P27/02
摘要： The present invention relates to a method preparing co-colloidal dispersions of active hydrophobic substances, such as pharmaceutical products, products having cosmetic properties or any other chemical product. The co-colloidal dispersions thus obtained are characterized in that they are formed by amphiphilic complexes resulting from combinations by non-covalent bonds between a hydrophobic active substance and a suitable hydrophilic molecule.
摘要翻译： 本发明涉及一种制备活性疏水物质如药物产品，具有化妆品特性的产品或任何其它化学产品的共胶体分散体的方法。 由此获得的共胶体分散体的特征在于它们由通过疏水性活性物质和合适亲水性分子之间的非共价键的组合产生的两亲性复合物形成。
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公开(公告)号：US20090233941A1
公开(公告)日：2009-09-17
申请号：US12226418
申请日：2007-04-18
IPC分类号： A61K31/506 , A61K31/155 , A61K31/245 , A61K31/138 , A61K31/4178 , C07C309/43
CPC分类号： A61K31/661 , A61K31/695 , C07C217/60 , C07C229/60 , C07C279/265 , C07C309/43 , C07C2603/54 , C07F9/6561
摘要： This invention relates to co-crystals of at least one molecule of calyx[n]arene or at least one of its derivatives, and at least one biologically active molecule, compositions and medicines including them, and the use of these co-crystals and methods used to obtain them.
摘要翻译： 本发明涉及至少一种分子的花萼[n]芳烃或其至少一种衍生物和至少一种生物活性分子，组合物和包括它们的药物的共晶体，以及这些共晶体和方法的用途 用来获取它们。
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公开(公告)号：US20100056482A1
公开(公告)日：2010-03-04
申请号：US12226449
申请日：2007-04-18
申请人： William Anthony Coleman , Loris Gilbert Baggetto , Adina Nicoleta Lazar , Mickael Henri Michaud , Sandrine Magnard
发明人： William Anthony Coleman , Loris Gilbert Baggetto , Adina Nicoleta Lazar , Mickael Henri Michaud , Sandrine Magnard
IPC分类号： A61K31/6615 , A61P35/00 , A61P35/02 , C07F9/09
CPC分类号： C07F9/6561
摘要： This invention relates to compounds having the following formula (I): of compositions including them, uses of these compounds, particularly for preparation of medicines, and in vitro induction processes for apoptosis and direct death of cancer cells.
摘要翻译： 本发明涉及具有下式（I）的化合物：包括它们的组合物，这些化合物的用途，特别是用于制备药物，以及用于细胞凋亡和癌细胞直接死亡的体外诱导过程。
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