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公开(公告)号:US07432343B2
公开(公告)日:2008-10-07
申请号:US11585030
申请日:2006-10-23
CPC分类号: C07K16/18 , C07K14/4702 , G01N33/574 , G01N33/57407 , G01N33/57415 , G01N33/57484 , G01N33/57496 , G01N33/6863 , G01N2333/4703 , G01N2500/00
摘要: The present invention provides nucleic acids. Polypeptides, antibodies and cells related to MAIL (Molecule possessing Ankyrin repeats Induced by LPS; or IκB-ζ), a novel member of the IκB family, expressed in LPS stimulated monocytes and uses thereof. The isolated nucleic acids, polypeptides, antibodies and cells of the invention can be used in detection assays, screening methods and drug discovery assays.
摘要翻译: 本发明提供核酸。 与LPS相关的多肽,抗体和细胞(由LPS诱导的锚蛋白重复的分子;或IkappaB-zeta),IkappaB家族的新成员,以LPS刺激的单核细胞及其用途表达。 本发明的分离的核酸,多肽,抗体和细胞可用于检测测定,筛选方法和药物发现测定。