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公开(公告)号:US20070015756A1
公开(公告)日:2007-01-18
申请号:US11383229
申请日:2006-05-15
申请人: Amogh Boloor , Mui Cheung , Ronda Davis , Philip Harris , Kevin Hinkle , Robert Mook , Jeffery Stafford , James Veal
发明人: Amogh Boloor , Mui Cheung , Ronda Davis , Philip Harris , Kevin Hinkle , Robert Mook , Jeffery Stafford , James Veal
IPC分类号: A61K31/53 , A61K31/506 , C07D403/02
CPC分类号: C07D239/30 , C07D231/56 , C07D235/08 , C07D403/12 , C07D413/14
摘要: Pyrimidine derivatives, which are useful as VEGFR2 inhibitors are described herein. The described invention also includes methods of making such pyrimidine derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.
摘要翻译: 本文描述了可用作VEGFR2抑制剂的嘧啶衍生物。 所述的发明还包括制备此类嘧啶衍生物的方法以及使用该嘧啶衍生物的方法来治疗过度增殖性疾病。
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公开(公告)号:US20070292513A1
公开(公告)日:2007-12-20
申请号:US11830608
申请日:2007-07-30
申请人: Amogh Boloor , Mui Cheung , Ronda Davis , Philip Harris , Kevin Hinkle , Robert Mook , Jeffery Stafford , James Veal
发明人: Amogh Boloor , Mui Cheung , Ronda Davis , Philip Harris , Kevin Hinkle , Robert Mook , Jeffery Stafford , James Veal
IPC分类号: C07D403/12 , A61K31/506 , A61K9/28 , A61P35/00 , C07D231/56
CPC分类号: C07D239/30 , C07D231/56 , C07D235/08 , C07D403/12 , C07D413/14
摘要: Pyrimidine derivatives, which are useful as VEGFR2 inhibitors are described herein. The described invention also includes methods of making such pyrimidine derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.
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公开(公告)号:US20070270427A1
公开(公告)日:2007-11-22
申请号:US11830024
申请日:2007-07-30
申请人: Amogh Boloor , Mui Cheung , Ronda Davis , Philip Harris , Kevin Hinkle , Robert Mook , Jeffery Stafford , James Veal
发明人: Amogh Boloor , Mui Cheung , Ronda Davis , Philip Harris , Kevin Hinkle , Robert Mook , Jeffery Stafford , James Veal
IPC分类号: A61K31/53 , A61P35/00 , C07D401/12
CPC分类号: C07D239/30 , C07D231/56 , C07D235/08 , C07D403/12 , C07D413/14
摘要: Pyrimidine derivatives, which are useful as VEGFR2 inhibitors are described herein. The described invention also includes methods of making such pyrimidine derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.
摘要翻译: 本文描述了可用作VEGFR2抑制剂的嘧啶衍生物。 所述的发明还包括制备此类嘧啶衍生物的方法以及使用该嘧啶衍生物的方法来治疗过度增殖性疾病。
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