公开(公告)号：US20240094200A1

公开(公告)日：2024-03-21

申请号：US17947007

申请日：2022-09-16

Applicant: Analog Devices, Inc.

Inventor： Alexander C. STANGE ,  Mohamed AZIZE ,  Hari CHAUHAN

IPC: G01N33/543 ,  G01N33/531

CPC classification number: G01N33/54353 ,  G01N33/531

Abstract: The present disclosure provides a method of fabricating a target capture and sensor assembly. The method comprises the steps of: providing a fluid path with a target capture surface comprising an anchor species with a first functional group disposed thereon; providing a target capture species to the target capture surface of the fluid path, wherein each target capture species comprises a target capture part and a second functional group configured to react with the first functional group; and exposing at least a portion of the target capture surface of the fluid path to photo radiation so as to cause a photo-initiated reaction between the first functional group and the second functional group, wherein the target capture and sensor assembly further comprises a sensing surface in the fluid path and wherein the target capture surface and the sensing surface are in fluid communication with one another.

公开(公告)号：US20240094154A1

公开(公告)日：2024-03-21

申请号：US18189717

申请日：2023-03-24

Applicant: Analog Devices, Inc.

Inventor： Alexander C. STANGE ,  Mohamed AZIZE ,  Hari CHAUHAN

IPC: G01N27/12 ,  B01L3/00

CPC classification number: G01N27/125 ,  B01L3/502707 ,  B01L3/502715

Abstract: The present disclosure provides a method of fabricating a sensor assembly in which a sensor surface has an anchor species provided thereon, the anchor species having a first functional group attached. The method further comprises disposing a fluid channel over the surface and subsequently providing an analyte capture species to the fluid channel. The analyte capture species comprises a second functional group configured to react with the first functional group. The surface is then exposed to photo radiation and the first and second functional groups react forming a link between the analyte capture species and the anchor species on the sensing surface.

公开(公告)号：US20250085254A1

公开(公告)日：2025-03-13

申请号：US18717282

申请日：2022-12-06

Applicant: Analog Devices, Inc.

Inventor： Hari CHAUHAN ,  Alexander C. STANGE ,  Mohamed AZIZE

IPC: G01N27/414 ,  G01N27/12 ,  G01N27/327

Abstract: The present disclosure provides a sensor assembly for detecting the presence of at least one amplification product of an isothermal amplification process (i.e., an isothermal nucleic acid amplification process). The sensor assembly includes a first sensor responsive to the detection of an indicator of the presence of at least one amplification product to provide a first signal, the first sensor comprising a sensing surface arranged to contact a sample in the amplification product receiving region, the sensing surface comprises a first layer comprising a one-dimensional or two-dimensional material. Alternatively or additionally, the disclosure provides a pH sensor comprising a sensing surface comprising a first layer comprising a one-dimensional or two-dimensional material.