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8 条记录 (耗时 0.014 秒)

    IRRADIATION APPARATUS AND TREATMENT
    1.
    发明申请
    IRRADIATION APPARATUS AND TREATMENT 审中-公开
    辐射装置和处理

    公开(公告)号：US20110288617A1

    公开(公告)日：2011-11-24

    申请号：US13063136

    申请日：2009-09-09

    申请人： Anant Sharma

    发明人： Anant Sharma

    IPC分类号： A61N5/06

    CPC分类号： A61L2/0047 ,  A61N5/0603 ,  A61N5/0616 ,  A61N5/0624 ,  A61N2005/0612 ,  A61N2005/063 ,  A61N2005/0642 ,  A61N2005/0644 ,  A61N2005/0651 ,  A61N2005/0661

    摘要： Infections of body tissues, particularly of the eye or of wounds, are treated by brief low-intensity irradiation with ultraviolet radiation in the UVC band. A suitable treatment device contains a light-emitting diode producing UVC radiation at a wavelength of about 265 nm, at a power output of 5 mW, directed on to a zone of tissue about 4 mm in diameter. An optical aiming system indicates the zone of tissue to be irradiated. Irradiation for periods as brief as 1 second has been found effective, which equates to a dose of 4 mJ/cm2 delivered to the tissue. Longer periods and higher intensities may be used for more resistant infections. Such irradiation may be delivered endoscopically to treat internal infections or to prevent infection during surgery. The device may be hand held or mounted to an ophthalmic slit lamp or other support.

    摘要翻译： 身体组织，特别是眼睛或伤口的感染，通过UVC带中的紫外线辐射的短暂的低强度照射来治疗。 合适的治疗装置包含发射二极管，其以约265nm的波长产生UVC辐射，功率输出为5mW，针对直径约4mm的组织区域。 光学瞄准系统指示要照射的组织的区域。 已经发现短暂1秒钟的照射是有效的，其等同于递送至组织的4mJ / cm 2的剂量。 更长的时间和更高的强度可用于更多的耐药性感染。 这种照射可以内窥镜递送以治疗内部感染或防止手术期间的感染。 该装置可以是手持的或安装到眼科裂隙灯或其它支架上。

    COMBINATION MEDICAMENT
    5.
    发明申请
    COMBINATION MEDICAMENT 审中-公开
    组合药物

    公开(公告)号：US20120165299A1

    公开(公告)日：2012-06-28

    申请号：US13394171

    申请日：2010-09-03

    申请人： Anant Sharma

    发明人： Anant Sharma

    IPC分类号： A61K31/573 ,  A61P37/08 ,  A61K31/616 ,  A61K31/57 ,  A61P29/00 ,  A61P27/02

    CPC分类号： A61K45/06 ,  A61K9/0048 ,  A61K31/196 ,  A61K31/381 ,  A61K31/407 ,  A61K31/47 ,  A61K31/573 ,  A61K2300/00

    摘要： A medicament for treating inflammation of human or animal body tissues contains a steroid, typically a corticosteroid, in combination with a non-steroidal anti-inflammatory drug (NSAID), typically a cyclooxygenase (COX-1 or COX-2) inhibitor. The medicament is of a particular effectiveness in treating inflammation of and around the eyes, whether caused by infection, irritation or surgery. Further medicaments combine an NSAID with antihistamines or with mast cell stabilisers. The medicaments are particularly effective in topically-applicable form, although other forms of application should also show benefits.

    摘要翻译： 用于治疗人或动物体组织的炎症的药物含有类固醇，通常为皮质类固醇，与非甾体抗炎药（NSAID），通常为环加氧酶（COX-1或COX-2）抑制剂组合。 该药物在治疗眼睛周围和周围的炎症方面特别有效，无论是由感染，刺激或手术引起的。 其他药物将NSAID与抗组胺药或肥大细胞稳定剂结合。 药物在局部适用形式中特别有效，尽管其他形式的应用也应显示益处。

    OPTICAL CORRECTION
    6.
    发明申请
    OPTICAL CORRECTION 审中-公开
    光学校正

    公开(公告)号：US20090156606A1

    公开(公告)日：2009-06-18

    申请号：US12334916

    申请日：2008-12-15

    申请人： Anant Sharma

    发明人： Anant Sharma

    IPC分类号： A61K31/498 ,  A61K31/4178 ,  A61K31/4168 ,  A61K31/496

    摘要： The present disclosure describes compositions which improve visual acuity and to methods for their use.

    摘要翻译： 本公开描述了改善视力的组合物及其使用方法。

    Method of treating an eye infection using electromagnetic radiation in the UVC
    7.
    发明授权
    Method of treating an eye infection using electromagnetic radiation in the UVC 有权
    在UVC中使用电磁辐射治疗眼部感染的方法

    公开(公告)号：US09474811B2

    公开(公告)日：2016-10-25

    申请号：US13063136

    申请日：2009-09-09

    申请人： Anant Sharma

    发明人： Anant Sharma

    IPC分类号： A61B19/00 ,  A61N5/06 ,  A61L2/00

    CPC分类号： A61L2/0047 ,  A61N5/0603 ,  A61N5/0616 ,  A61N5/0624 ,  A61N2005/0612 ,  A61N2005/063 ,  A61N2005/0642 ,  A61N2005/0644 ,  A61N2005/0651 ,  A61N2005/0661

    摘要： Infections of body tissues, particularly of the eye or of wounds, are treated by brief low-intensity irradiation with ultraviolet radiation in the UVC band. A suitable treatment device contains a light-emitting diode producing UVC radiation at a wavelength of about 265 nm, at a power output of 5 mW, directed on to a zone of tissue about 4 mm in diameter. An optical aiming system indicates the zone of tissue to be irradiated. Irradiation for periods as brief as 1 second has been found effective, which equates to a dose of 4 mJ/cm2 delivered to the tissue. Longer periods and higher intensities may be used for more resistant infections. Such irradiation may be delivered endoscopically to treat internal infections or to prevent infection during surgery. The device may be hand held or mounted to an ophthalmic slit lamp or other support.

    摘要翻译： 身体组织，特别是眼睛或伤口的感染，通过UVC带中的紫外线辐射的短暂的低强度照射来治疗。 合适的治疗装置包含发射二极管，其以约265nm的波长产生UVC辐射，功率输出为5mW，针对直径约4mm的组织区域。 光学瞄准系统指示要照射的组织的区域。 已经发现短暂1秒钟的照射是有效的，其等同于递送至组织的4mJ / cm 2的剂量。 更长的时间和更高的强度可用于更多的耐药性感染。 这种照射可以内窥镜递送以治疗内部感染或防止手术期间的感染。 该装置可以是手持的或安装到眼科裂隙灯或其它支架上。

    OPHTHALMIC TREATMENTS
    8.
    发明申请
    OPHTHALMIC TREATMENTS 审中-公开
    眼科治疗

    公开(公告)号：US20140088199A1

    公开(公告)日：2014-03-27

    申请号：US14009397

    申请日：2012-04-05

    申请人： Anant Sharma

    发明人： Anant Sharma

    IPC分类号： A61K31/137

    CPC分类号： A61K31/137 ,  A61K9/0048 ,  A61K9/06 ,  A61K9/08 ,  A61K31/135 ,  A61K31/4178 ,  A61K45/06 ,  A61K2300/00

    摘要： Aqueous compositions suitable for topical administration to the human or animal eye contain at least one water-soluble polymeric ophthalmic lubricant, such as hyaluronate, carbomer gel or hypromellose, together with a water-soluble analgesic. The analgesic may be an opiod, particularly an opioid having an affinity for 5-HT receptors, such as tramadol. Typical tramadol levels would be in the range of 0.5% to 1.0% w/v. The aqueous compositions may for example be used as artificial tears, and as general ophthalmic lubricants for treating conditions such as dry eye or blepharitis. Further compositions combine ophthalmologically-active agents, such as pharmaceuticals, with opioids, such as tramadol in particular. These compositions may be used to treat the eye while reducing pain or discomfort that would normally be produced by administering these particular pharmaceuticals to the eye, and increasing the efficacy of the pharmaceuticals. Compositions are also disclosed, containing opioids with 5-HT receptor activity, which are of general use in alleviating pain in and around the eye.

    摘要翻译： 适于局部施用于人或动物眼睛的水性组合物含有至少一种水溶性聚合物眼用润滑剂，例如透明质酸盐，卡波姆凝胶或羟丙甲纤维素，以及水溶性镇痛剂。 止痛剂可以是阿片类药物，特别是对5-HT受体具有亲和力的阿片样物质，如曲马多。 典型的曲马多水平将在0.5％至1.0％w / v的范围内。 水性组合物可以例如用作人造泪液，以及用作治疗诸如干眼症或睑炎的病症的一般眼用润滑剂。 其它组合物将眼科活性剂如药物与阿片样物质组合，特别是曲马多组合。 这些组合物可用于治疗眼睛，同时减少通常通过将这些特定药物施用于眼睛产生的疼痛或不适，并增加药物的功效。 还公开了含有具有5-HT受体活性的阿片样物质的组合物，其通常用于缓解眼睛中和眼睛周围的疼痛。