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公开(公告)号:US12109428B2
公开(公告)日:2024-10-08
申请号:US17675134
申请日:2022-02-18
Applicant: MUREVA PHOTOTHERAPY, INC.
Inventor: Vedang Kothari , Peter W. Broer
CPC classification number: A61N5/0603 , A61N5/0624 , A61B2017/00035 , A61B2017/00084 , A61B2018/00791 , A61B2018/00839 , A61B2090/034 , A61N2005/005 , A61N2005/0606 , A61N2005/0626 , A61N2005/063 , A61N2005/0645 , A61N2005/0651 , A61N2005/0666
Abstract: Intraoral phototherapy devices receive light from an associated light source and propagate the light into an oral cavity of a patient. The device comprises a light guide that receives light from an external light source. The light guide comprises a main body portion made of an optically transparent soft flexible biocompatible polymeric material sized and shaped to conform to contours of the oral cavity when inserted therein to direct the light to targeted regions of the oral cavity. The main body portion comprises a pair of spaced apart side wings sized and shaped to be received between a patient's teeth and cheeks on opposite sides of the oral cavity and a center flap intermediate the side wings for transmitting and directing the light to targeted regions of the oral cavity. A controller delivers light to the light guide in a controlled manner.
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公开(公告)号:US12090336B2
公开(公告)日:2024-09-17
申请号:US17600753
申请日:2020-04-03
Applicant: Lumitex, Inc.
Inventor: Michael Kerns , David G. Felty , Peter Broer
IPC: A61N5/06
CPC classification number: A61N5/0621 , A61N2005/0626 , A61N2005/063 , A61N2005/0637 , A61N2005/0651
Abstract: A phototherapy system having sensor(s) for detecting parameters associated with light generation by a light source and circuitry for modulating the light source based on the detected parameters. Also, a phototherapy system having a light guide interfacing with a light source at a connection point, an ambient light sensor, a connector light sensor for detecting (at the connection point) ambient light received by a light emitting pad that is directed into the light guide, and circuitry for determining whether the light guide is correctly connected to the light source based on a difference between the output of the ambient light source and the connector light sensor. Further, a phototherapy system including a light emitting pad having an identification tag and circuitry that modulates a light source based on the identification tag. Additionally, a phototherapy system including a casing encapsulating multiple light emitters and a light emitting pad.
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公开(公告)号:US12083353B2
公开(公告)日:2024-09-10
申请号:US17724343
申请日:2022-04-19
Applicant: IPG Photonics Corporation
Inventor: Gregory Altshuler , Christopher Gaal , Valery Kozlov
CPC classification number: A61N5/06 , G02B6/3624 , G02B6/3861 , G02B6/3882 , G02B6/3893 , G02B6/3897 , G02B6/4206 , G02B6/4292 , G02B6/4295 , A61B18/22 , A61N2005/063 , A61N2005/0632 , A61N5/067 , G02B6/3887
Abstract: A delivery system extends from a laser radiation source for connecting to a medical device that utilizes the laser radiation for medical treatment. The delivery system comprises an optical fiber connecting to a male launch connecter. The male launch connector having a body portion with the optical fiber fixed or constrained therein and the optical fiber terminating at a male ferrule with a forward directed fiber facet, the male ferrule may be cantilevered within the body portion by the optical fiber line providing freedom of movement of the male ferrule. The launch connector engages a receiving connector on the medical device first with mechanical connection portions and then more finely aligning optical connection portions by the male ferrule self aligning in a female ferrule with cooperating tapered surfaces. The male portion may fully seat in the female portion with cooperating cylindrical surfaces.
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公开(公告)号:US12076578B2
公开(公告)日:2024-09-03
申请号:US17263171
申请日:2019-08-09
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor: Jonathan Alambra Palero , Frank Anton Van Abeelen , Bastiaan Wilhelmus Maria Moeskops , Yannyk Parulian Julian Bourquin , Kiran Kumar Thumma
CPC classification number: A61N5/0617 , A61N2005/005 , A61N2005/063 , A61N2005/0644
Abstract: According to an aspect, there is provided a hand-held skin treatment device (2) for applying light to skin of a subject to perform a treatment operation. The hand-held device (2) comprises a rigid main housing (4) accommodating a cooling unit (19); a first treatment head portion (12) coupled to the main housing (4) for performing the treatment operation on a first skin portion, wherein the first treatment head portion (12) comprises a first optical waveguide (16) having a first skin-contact surface (17) with a first total surface area, a first light source (14) for generating light and applying the light to the first skin portion via the first optical waveguide (16) and the first skin-contact surface (17), and a first heat sink (18) thermally coupled to the first light source (14) and to the cooling unit (19); a second treatment head portion (20) for performing the treatment operation on a second skin portion adjacent to the first skin portion, wherein the second treatment head portion (20) comprises a second optical waveguide (24) having a second skin-contact surface (25) with a second total surface area, a second light source (22) for generating light and applying the light to the second skin portion via the second optical waveguide (24) and the second skin-contact surface (25), and a second heat sink (26) thermally coupled to the second light source (22); wherein the hand-held device (2) is operable in (i) a first configuration in which the first and second treatment head portions (12; 20) are in a first spatial arrangement relative to the main housing (4) such that, in an operational position of the main housing (4) relative to the skin, only the first skin-contact surface (17) is arranged in a treatment position relative to the main housing (4) such as to be able to contact the skin over the first total surface area; and (ii) a second configuration in which the second treatment head portion (20) is coupled to the main housing (4) and the second heat sink (26) is thermally coupled to the cooling unit (19), and in which the first and second treatment head portions (12; 20) are in a second spatial arrangement relative to the main housing (4), different from the first spatial arrangement, such that, in the operational position of the main housing (4), the first skin-contact surface (17) and the second skin-contact surface (25) are each arranged in a treatment position relative to the main housing (4) such as to be able to contact the skin over, respectively, the first total surface area and the second total surface area.
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公开(公告)号:US20240261023A1
公开(公告)日:2024-08-08
申请号:US18563823
申请日:2022-03-25
Applicant: Universite de Bordeaux , INSERM (Institut National de la Santé et de la Recherche Medicale) , Fondation Bordeaux Universite
Inventor: Bruno Quesson
IPC: A61B18/22 , A61B5/01 , A61B5/055 , A61B18/00 , A61B18/20 , A61N5/00 , A61N5/06 , A61N5/067 , G01K11/32
CPC classification number: A61B18/22 , A61B5/015 , A61B5/055 , A61N5/062 , A61N5/067 , G01K11/32 , A61B2018/00023 , A61B2018/00351 , A61B2018/00702 , A61B2018/00714 , A61B2018/00791 , A61B2018/2065 , A61B2018/2211 , A61N2005/005 , A61N2005/0626 , A61N2005/063
Abstract: A laser device for treating a target region of biological tissue comprises: a sheath; at least two optical fibers in the sheath, each configured to guide a laser beam to the target region, distal ends of at least two of the optical fibers configured so that each emits a laser beam in a different direction; a system of laser sources configured to generate at least two laser beams, the two laser beams having different or identical wavelengths with adjustable power; and a laser-beam control unit configured to control the system of laser sources so as to select the wavelength, the power, the duration of the deposition of laser energy, and the moment of emission of each of the laser beams in the direction of the target region so as to dynamically generate and adjust a 3D thermal distribution having a geometric shape matching a geometric shape of the target region.
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公开(公告)号:US12048508B2
公开(公告)日:2024-07-30
申请号:US18001009
申请日:2021-06-08
Applicant: Lumeda Inc.
Inventor: Trevor MacDougall , Yi Yang
CPC classification number: A61B5/0059 , A61N5/0601 , A61N2005/063
Abstract: An interoperative light therapy apparatus and method are disclosed. The apparatus includes an excitation light source, a plurality of light emitting devices and a plurality of light detecting fibers, wherein the plurality of light emitting devices produce a fluorescence light in cancerous cells of a patient treated with a photosensitizing medication. The fluorescence light is collected by the plurality of detector fibers and a digital spatial image of the cancerous cells is produced. The digital spatial image is useful for targeting the cancerous cells in a subsequent resection procedure. An interoperative light therapy apparatus is disclosed that further include a therapy light source that can deliver therapy light to the cancerous cells using the digital spatial image in the subsequent resection procedure.
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公开(公告)号:US20240238611A1
公开(公告)日:2024-07-18
申请号:US18567997
申请日:2022-06-07
Applicant: W. L. Gore & Associates, Inc.
Inventor: Merrill J. Birdno , Jared S. Nelson , Brandon C. Short
CPC classification number: A61N5/062 , A61K9/7084 , A61K41/0057 , A61N2005/0602 , A61N2005/063 , A61N2005/0632 , A61N2005/0645 , A61N2005/0661 , A61N2005/0663
Abstract: Described embodiments are directed to a device, system, and methods for delivery of activatable compounds to a patient's tissue. More specifically, described embodiments are directed toward delivery devices operable to deliver the activatable compounds and to activate the compounds. Such delivery devices may include treatment zones for activatable compound delivery and/or activation and non-treatment zones that block activatable compound delivery and/or activation for controlled delivery and activation of the activatable compounds.
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公开(公告)号:US11986669B2
公开(公告)日:2024-05-21
申请号:US18153000
申请日:2023-01-11
Applicant: ACUCELA INC.
Inventor: Ryo Kubota , Karim Haroud , Beat Wyss , Hans Bernhard , Jean-Noel Fehr , Patrizia Weber , Moritz Haeberli , Amitava Gupta
CPC classification number: A61N5/0622 , G02B27/0172 , G02B27/30 , A61N2005/063 , A61N2005/0648 , A61N2005/0652 , A61N2005/0663 , G02B2027/0178
Abstract: A device to stimulate the retina comprises one or more light sources coupled to one or more optical elements. The one or more optical elements is configured to illuminate the retina with one or more images at a location away from a fovea of a wearer. In some embodiments, each of the one or more images comprises a depth of focus and a spatial resolution. The one or more images can be formed at a distance anterior to the retina, at a distance posterior to the retina or on the retina. In some embodiments, the depth of focus is less than the distance, and the spatial resolution greater than a spatial resolution of the retina at the location.
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公开(公告)号:US20240134104A1
公开(公告)日:2024-04-25
申请号:US17776436
申请日:2022-03-22
Inventor: Hyun Wook KANG
CPC classification number: G02B6/0008 , A61N5/0603 , A61N5/067 , A61N2005/0609 , A61N2005/063
Abstract: The present disclosure relates to an optical transfer device for tissue treatment. An optical transfer device of the present disclosure includes an optical probe having a light divergence part at the longitudinal end thereof, and a coating part configured to surround the optical probe, wherein the coating part includes a light diffusion part formed at the end thereof configured to cover the light divergence part, the light diffusion part having multiple grooves formed thereon.
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公开(公告)号:US11957897B2
公开(公告)日:2024-04-16
申请号:US15495959
申请日:2017-04-24
Applicant: Newton Howard
Inventor: Newton Howard
IPC: A61N1/05 , A61B5/00 , A61L27/38 , A61N5/06 , B82Y15/00 , G01N21/17 , G01N27/414 , A61N5/067 , B82Y5/00
CPC classification number: A61N1/0529 , A61L27/383 , A61N5/0622 , B82Y15/00 , G01N21/1702 , G01N27/4145 , A61B5/0093 , A61N1/0531 , A61N5/06 , A61N2005/0611 , A61N2005/063 , A61N5/067 , B82Y5/00
Abstract: Embodiments may provide a general-purpose, relatively inexpensive, AI-driven implant that is able to adapt to and modulate any given neuron, circuit, or region in the brain, as well as individual cells of any type of tissue. For example, in an embodiment, a method for interacting with living tissue may comprise attaching a device to a body of a person or animal, the device comprising plurality of carbon fibers in contact with the living tissue, receiving by the carbon fibers signals from the living tissue, processing the received signals by the device, and transmitting the processed signals.
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