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    Arrhythmia Classification
    1.
    发明申请
    Arrhythmia Classification 审中-公开
    心律失常分类

    公开(公告)号：US20130046194A1

    公开(公告)日：2013-02-21

    申请号：US13643068

    申请日：2010-04-27

    申请人： Anders Bjolring ,  Malin Hollmark ,  Tomas Svensson ,  Stefan Hjelm ,  Kjell Noren ,  Karin Jarverud

    发明人： Anders Bjolring ,  Malin Hollmark ,  Tomas Svensson ,  Stefan Hjelm ,  Kjell Noren ,  Karin Jarverud

    IPC分类号： A61B5/0452 ,  A61N1/39

    CPC分类号： A61B5/0452 ,  A61B5/053 ,  A61B5/0538 ,  A61B5/7257 ,  A61B5/7264 ,  A61N1/3622 ,  A61N1/36521 ,  A61N1/36564 ,  A61N1/36585 ,  A61N1/3962

    摘要： An implantable medical device (100) is configured for generating a cardiogenic impedance signal representative of the cardiogenic impedance of at least a portion of a heart (10) of a subject (20) during multiple cardiac cycles. A transform processor (132) generates a spectrum signal by applying a time-to-frequency transform to the cardiogenic impedance signal. The spectrum signal is processed by a distribution processor (133) configured to calculate a distribution parameter indicative of a distribution in at least a portion of the spectrum signal. The calculated distribution parameter is of high diagnostic value and is employed by an arrhythmia classifier (134) in order to classify a detected arrhythmia of the heart (10), such as discriminate between hemodynamically stable or unstable arrhythmias and/or supraventricular or ventricular tachycardia.

    摘要翻译： 可植入医疗装置（100）被配置为在多个心动周期期间产生代表受试者（20）的心脏（10）的至少一部分的心源阻抗的心源阻抗信号。 变换处理器（132）通过对心源阻抗信号施加时间 - 频率变换来产生频谱信号。 频谱信号由分配处理器（133）处理，分配处理器（133）被配置为计算指示频谱信号的至少一部分中的分布的分布参数。 计算出的分布参数具有很高的诊断价值，并被心律失常分类器（134）采用，以便将检测到的心脏心律不齐（10）进行分类，例如区分血流动力学稳定或不稳定的心律失常和/或室上或室性心动过速。

    ARRHYTHMIA CLASSIFICATION
    4.
    发明申请
    ARRHYTHMIA CLASSIFICATION 有权
    ARRHYTHMIA分类

    公开(公告)号：US20110245701A1

    公开(公告)日：2011-10-06

    申请号：US13076627

    申请日：2011-03-31

    申请人： Anders Bjorling ,  Malin Hollmark ,  Tomas Svensson ,  Stefan Hjelm ,  Kjell Noren ,  Karin Jarverud

    发明人： Anders Bjorling ,  Malin Hollmark ,  Tomas Svensson ,  Stefan Hjelm ,  Kjell Noren ,  Karin Jarverud

    IPC分类号： A61B5/0456 ,  A61N1/39

    CPC分类号： A61B5/0456 ,  A61B5/0031 ,  A61B5/053 ,  A61B5/7264 ,  A61N1/3621 ,  A61N1/36521 ,  A61N1/3702 ,  A61N1/3925 ,  A61N1/3962

    摘要： An implantable medical device, is designed to collect a signal representative of the electric activity of the heart and determine a cardiogenic impedance signal for at least a portion of the heart. An R-wave detector of the IMD detects the timing of an R-wave during a cardiac cycle based on the signal representative of the electric activity. A minimum detector detects the timing of a cardiogenic impedance minimum in the cardiogenic impedance signal and within a systolic time window of the cardiac cycle. A detected arrhythmia is then classified by the IMD based on the timing of the R-wave detected by the R-wave detector and the timing of the cardiogenic impedance minimum detected by the minimum detector.

    摘要翻译： 可植入医疗装置被设计成收集表示心脏的电活动的信号，并确定至少一部分心脏的心源性阻抗信号。 基于代表电活动的信号，IMD的R波检测器在心动周期中检测R波的定时。 最小检测器检测心源性阻抗信号中心源性阻抗最小值的定时，并在心动周期的收缩时间窗内检测。 然后，基于由R波检测器检测到的R波的定时和由最小检测器检测的心源阻抗最小值的定时，通过IMD对检测到的心律失常进行分类。

    HEMODYNAMIC STATUS ASSESSMENT
    5.
    发明申请
    HEMODYNAMIC STATUS ASSESSMENT 有权
    动态状态评估

    公开(公告)号：US20130325359A1

    公开(公告)日：2013-12-05

    申请号：US14000844

    申请日：2011-03-18

    申请人： Karin Jarverud ,  Anders Bjorling ,  Malin Hollmark ,  Kjell Noren ,  Tomas Svensson ,  Stefan Hjelm

    发明人： Karin Jarverud ,  Anders Bjorling ,  Malin Hollmark ,  Kjell Noren ,  Tomas Svensson ,  Stefan Hjelm

    IPC分类号： G06F19/00

    CPC分类号： G06F19/34 ,  A61B5/0464 ,  A61B5/0538 ,  A61N1/36521 ,  A61N1/36535 ,  G06F19/00 ,  G06F19/12 ,  G06F19/24 ,  G16H50/50

    摘要： A patient-specific hemodyanmic status model is determined from impedance data collected during periods of normal and abnormal hemodynamic status by deriving parameter values of a set of multiple impedance-derivable parameters from impedance signals collected during periods of normal hemodynamic status and in connection with periods of abnormal hemodynamic status. The parameter values are employed to estimate coefficients of a linear parametric status model. These coefficients can then be used together with parameter values determined from impedance signals determined during status assessment periods in order to determine a current hemdoynamic status of the patient.

    摘要翻译： 通过从正常血液动力学状态期间收集的阻抗信号中导出一组多个阻抗可导出参数的参数值，并与正常血液动力学状态期间相关联的时期，从正常和异常血液动力学状态期间收集的阻抗数据确定患者特异性血液动力学状态模型 异常血液动力学状态。 参数值用于估计线性参数状态模型的系数。 然后可以将这些系数与在状态评估周期期间确定的阻抗信号确定的参数值一起使用，以便确定患者的当前血液动力学状态。

    IMPLANTABLE MEDICAL DEVICE AND METHOD COMPRISING MEANS FOR DETECTING AND CLASSIFYING AN ARRHYTHMIA
    6.
    发明申请
    IMPLANTABLE MEDICAL DEVICE AND METHOD COMPRISING MEANS FOR DETECTING AND CLASSIFYING AN ARRHYTHMIA 有权
    可植入医疗装置和方法，包括用于检测和分类ARRHYTHMIA的手段

    公开(公告)号：US20130060118A1

    公开(公告)日：2013-03-07

    申请号：US13696261

    申请日：2010-05-12

    申请人： Anders Björling ,  Malin Hollmark ,  Tomas Svensson ,  Stefan Hjelm ,  Kjell Norén ,  Karin Järverud

    发明人： Anders Björling ,  Malin Hollmark ,  Tomas Svensson ,  Stefan Hjelm ,  Kjell Norén ,  Karin Järverud

    IPC分类号： A61N1/39 ,  A61B5/0245 ,  A61B5/053

    CPC分类号： A61N1/3621 ,  A61N1/3622 ,  A61N1/36521 ,  A61N1/3704 ,  A61N1/3962

    摘要： An implantable medical device (100) is configured for generating a cardiogenic impedance signal representative of the cardiogenic impedance of at least a portion of a heart (10) of a subject (20) during at least a portion of cardiac cycle. A moment processor (132) calculates a moment parameter value based on the cardiogenic impedance signal. The moment parameter is representative of a weighted sum of impedance amplitudes within a time window centered at defined time instance within the cardiac cycle. The weights of the impedance amplitudes are further dependent on the length in time between the defined time instance and the point of time of the associated impedance amplitude. The moment parameter is of high diagnostic value and is employed by an arrhythmia classifier (132) in order to classify a detected arrhythmia of the heart (10), such as discriminate between hemodynamically stable or unstable arrhythmias and/or supraventricular or ventricular tachycardia.

    摘要翻译： 可植入医疗装置（100）被配置为在心脏周期的至少一部分期间产生代表受试者（20）的心脏（10）的至少一部分的心源阻抗的心源性阻抗信号。 时刻处理器（132）基于心源阻抗信号计算力矩参数值。 力矩参数代表以心动周期内规定时间范围为中心的时间窗内的阻抗振幅加权和。 阻抗幅度的权重进一步取决于所定义的时间实例和相关联的阻抗幅度的时间点之间的时间长度。 时刻参数具有很高的诊断价值，并被心律失常分类器（132）采用，以便将检测到的心脏（10）的心律失常进行分类，例如区分血流动力学稳定或不稳定的心律失常和/或室上或室性心动过速。

    Implantable medical device and method comprising means for detecting and classifying an arrhythmia
    7.
    发明授权
    Implantable medical device and method comprising means for detecting and classifying an arrhythmia 有权
    可植入医疗装置和方法包括用于检测和分类心律失常的装置

    公开(公告)号：US08738120B2

    公开(公告)日：2014-05-27

    申请号：US13696261

    申请日：2010-05-12

    申请人： Anders Björling ,  Malin Hollmark ,  Tomas Svensson ,  Stefan Hjelm ,  Kjell Norén ,  Karin Järverud

    发明人： Anders Björling ,  Malin Hollmark ,  Tomas Svensson ,  Stefan Hjelm ,  Kjell Norén ,  Karin Järverud

    IPC分类号： A61B5/0468

    CPC分类号： A61N1/3621 ,  A61N1/3622 ,  A61N1/36521 ,  A61N1/3704 ,  A61N1/3962

    摘要： An implantable medical device (100) is configured for generating a cardiogenic impedance signal representative of the cardiogenic impedance of at least a portion of a heart (10) of a subject (20) during at least a portion of cardiac cycle. A moment processor (132) calculates a moment parameter value based on the cardiogenic impedance signal. The moment parameter is representative of a weighted sum of impedance amplitudes within a time window centered at defined time instance within the cardiac cycle. The weights of the impedance amplitudes are further dependent on the length in time between the defined time instance and the point of time of the associated impedance amplitude. The moment parameter is of high diagnostic value and is employed by an arrhythmia classifier (132) in order to classify a detected arrhythmia of the heart (10), such as discriminate between hemodynamically stable or unstable arrhythmias and/or supraventricular or ventricular tachycardia.

    摘要翻译： 可植入医疗装置（100）被配置为在心脏周期的至少一部分期间产生代表受试者（20）的心脏（10）的至少一部分的心源阻抗的心源性阻抗信号。 时刻处理器（132）基于心源阻抗信号计算力矩参数值。 力矩参数代表以心动周期内规定时间范围为中心的时间窗内的阻抗振幅加权和。 阻抗幅度的权重进一步取决于所定义的时间实例和相关联的阻抗幅度的时间点之间的时间长度。 时刻参数具有很高的诊断价值，并被心律失常分类器（132）采用，以便将检测到的心脏（10）的心律失常进行分类，例如区分血流动力学稳定或不稳定的心律失常和/或室上或室性心动过速。

    ISCHEMIC STATUS MONITORING
    8.
    发明申请
    ISCHEMIC STATUS MONITORING 审中-公开
    ISCHEMIC状态监测

    公开(公告)号：US20110319769A1

    公开(公告)日：2011-12-29

    申请号：US13255460

    申请日：2009-03-13

    申请人： Sven-Erik Hedberg ,  Tomas Svensson ,  Michael Broomé ,  Karin Järverud ,  Stefan Hjelm

    发明人： Sven-Erik Hedberg ,  Tomas Svensson ,  Michael Broomé ,  Karin Järverud ,  Stefan Hjelm

    IPC分类号： A61N1/365 ,  A61B5/026

    CPC分类号： A61B5/0452 ,  A61B5/026 ,  A61B5/053 ,  A61B5/1116 ,  A61B5/1118 ,  A61B5/4836 ,  A61B5/6846 ,  A61B5/7405 ,  A61B5/7455 ,  A61N1/3702

    摘要： An ischemia monitoring system has detectors for detecting the onset of an ischemic event of a tissue in subject, the end of the ischemic event and the end of a following recovery from the ischemic event, respectively. A time processor determines the duration of the ischemic event and the recovery period based on the detected onset and end times. A status processor co-processes the two determined time durations for the purpose of monitoring the ischemic status of the subject and detecting any deterioration in ischemic status for the latest ischemic event as compared to previous ischemic events that have occurred in the subject's tissue.

    摘要翻译： 缺血监测系统具有检测器，用于分别检测受试者组织的缺血事件的发作，缺血事件的结束以及从缺血事件中恢复的结束。 时间处理器基于检测到的开始和结束时间来确定缺血事件的持续时间和恢复期。 状态处理器协调处理两个确定的持续时间以便监测受试者的缺血状态并且检测与在受试者组织中发生的先前缺血事件相比，最新缺血事件的缺血状态的任何恶化。

    MEDICAL IMPLANTABLE DEVICE AND METHOD FOR CONNECTING AN ANTENNA TO THE SAME
    9.
    发明申请
    MEDICAL IMPLANTABLE DEVICE AND METHOD FOR CONNECTING AN ANTENNA TO THE SAME 有权
    医用可植入装置及其天线连接方法

    公开(公告)号：US20090163979A1

    公开(公告)日：2009-06-25

    申请号：US12091631

    申请日：2005-10-27

    申请人： Stefan Hjelm ,  Tomas Snitting ,  Wisit Lim ,  Kavous Sahabi

    发明人： Stefan Hjelm ,  Tomas Snitting ,  Wisit Lim ,  Kavous Sahabi

    IPC分类号： A61N1/08 ,  H05K9/00

    CPC分类号： A61N1/3754 ,  A61N1/37 ,  A61N1/3718 ,  A61N1/37229 ,  A61N1/3925

    摘要： In a medical implantable device having a hermetically sealed, radio shielded encapsulations containing an RF circuit therein and having an antenna located outside of the encapsulation, and in a method for connecting the RF circuit to the antenna, at least one hermetical feedthrough connection is provided in the form of at least one conductor passing through a wall portion of the encapsulation in a liquid-tight and gas-tight manner, with the feedthrough being electrically insulated from the encapsulation. At least one connector pin is provided on an RF circuit board, which is resiliently mounted on the RF circuit board. The RF circuit is mounted in the encapsulation so as to cause the connector pin to resiliently engage the conductor and to electrically connect the conductor with the RF circuit board.

    摘要翻译： 在具有气密密封的无线电屏蔽封装的医疗可植入装置中，其中包含RF电路并且具有位于封装外部的天线，并且在将RF电路连接到天线的方法中，至少提供一个密封馈通连接 至少一个导体以液密和气密的方式穿过封装的壁部分的形式，其中馈通与封装电绝缘。 至少一个连接器引脚设置在RF电路板上，RF电路板弹性地安装在RF电路板上。 RF电路安装在封装中，以使连接器引脚弹性地接合导体并将导体与RF电路板电连接。

    Medical implantable device and method for connecting an antenna to the same
    10.
    发明授权
    Medical implantable device and method for connecting an antenna to the same 有权
    用于将天线连接到其上的医用植入装置和方法

    公开(公告)号：US08126556B2

    公开(公告)日：2012-02-28

    申请号：US12091631

    申请日：2005-10-27

    申请人： Stefan Hjelm ,  Tomas Snitting ,  Wisit Lim ,  Kavous Sahabi

    发明人： Stefan Hjelm ,  Tomas Snitting ,  Wisit Lim ,  Kavous Sahabi

    IPC分类号： A61N1/08

    CPC分类号： A61N1/3754 ,  A61N1/37 ,  A61N1/3718 ,  A61N1/37229 ,  A61N1/3925

    摘要： In a medical implantable device having a hermetically sealed, radio shielded encapsulations containing an RF circuit therein and having an antenna located outside of the encapsulation, and in a method for connecting the RF circuit to the antenna, at least one hermetical feedthrough connection is provided in the form of at least one conductor passing through a wall portion of the encapsulation in a liquid-tight and gas-tight manner, with the feedthrough being electrically insulated from the encapsulation. At least one connector pin is provided on an RF circuit board, which is resiliently mounted on the RF circuit board. The RF circuit is mounted in the encapsulation so as to cause the connector pin to resiliently engage the conductor and to electrically connect the conductor with the RF circuit board.

    摘要翻译： 在具有气密密封的无线电屏蔽封装的医疗可植入装置中，其中包含RF电路并且具有位于封装外部的天线，并且在将RF电路连接到天线的方法中，至少提供一个密封馈通连接 至少一个导体以液密和气密的方式穿过封装的壁部分的形式，其中馈通与封装电绝缘。 至少一个连接器引脚设置在RF电路板上，RF电路板弹性地安装在RF电路板上。 RF电路安装在封装中，以使连接器引脚弹性地接合导体并将导体与RF电路板电连接。