公开(公告)号：US20060003983A1

公开(公告)日：2006-01-05

申请号：US11171076

申请日：2005-06-30

申请人： Andrei Reshetnikov ,  Igor Zalevsky ,  Jury Kemov ,  Andrei Ivanov ,  Artashes Karmenyan ,  Alexandr Gradjushko ,  Vladimir Laptev ,  Nataliya Neugodova ,  Olga Abakumova ,  Valery Privalov ,  Alexandr Lappa ,  Vladimir Romanov

发明人： Andrei Reshetnikov ,  Igor Zalevsky ,  Jury Kemov ,  Andrei Ivanov ,  Artashes Karmenyan ,  Alexandr Gradjushko ,  Vladimir Laptev ,  Nataliya Neugodova ,  Olga Abakumova ,  Valery Privalov ,  Alexandr Lappa ,  Vladimir Romanov

IPC分类号： A61K31/409 ,  A61K31/555 ,  C07D487/22

CPC分类号： A61K49/0013 ,  A61K41/0057 ,  A61K41/0071 ,  C07D487/22

摘要： The invention relates to medicine and concerns a photosensitizer for detecting and curing tumors. The inventive photosensitizer is embodied in the form of a composition containing chlorin in the form of salt and alkali metals. The chlorin is composed of 80-90% of chlorin e6, 5-20 of purpurin 5 and the rest being purpurin 18-chlorin p6. Said photosensitizer is produced by extracting Spirulina biomass with the aid of acetone. Afterwards said biomass is exposed to acid treatment, neutralization, hydrolysis, extraction of pheophorbide a, dissolution in acetone, addition of a strong base, neutralization and reprecipitation of chlorin e6.

摘要翻译： 本发明涉及药物，涉及用于检测和治愈肿瘤的光敏剂。 本发明的光敏剂以含有盐和碱金属形式的二氢卟酚的组合物的形式体现。 二氢卟酚由80％至90％的二氢卟酚，5-20的紫草素组成，其余为紫草素18-二氢卟酚6。 所述光敏剂是借助丙酮提取螺旋藻生物质来生产的。 之后，生物量暴露于酸处理，中和，水解，脱镁叶酸a的提取，丙酮溶解，加碱强碱，中和和二氢卟酚6重新沉淀。

公开(公告)号：US20070036482A1

公开(公告)日：2007-02-15

申请号：US10558519

申请日：2004-05-19

申请人： Sergey Goncharov ,  Igor Zalevsky

发明人： Sergey Goncharov ,  Igor Zalevsky

IPC分类号： G02B6/28

CPC分类号： G02B19/0057 ,  G02B19/0028 ,  G02B27/0966 ,  G02B27/0977 ,  H01S5/005 ,  H01S5/4025

摘要： The invention provides an optical multiplexing device comprising: a plurality of optical sources with integrated collimators (31-37) whose output beams are combined by mirrors (41-47) or other beam deflecting elements, which combine the beams into a single composite beam diverging from a common origin point (30). This is done by arranging the mirrors (41-47) staggered at different distances from the origin point, and at different angles to each other taking accourt of the dependence of the beam divergence in far field on the distance from the origin point.

摘要翻译： 本发明提供了一种光学多路复用装置，其包括：具有集成准直仪（31-37）的多个光源，其输出光束由反射镜（41-47）或其它光束偏转元件组合，其将光束组合成单个复合光束发散 从共同的起点（30）。 这通过将从原点不同距离交错的反射镜（41-47）布置成彼此不同的角度来实现远场处的光束发散的依赖关系。