公开(公告)号：US20080009042A1

公开(公告)日：2008-01-10

申请号：US11738582

申请日：2007-04-23

申请人： Andrew Goodey ,  Darell Sleep ,  Hendrik Van Urk ,  Stephen Berezenko ,  John Woodrow ,  Richard Johnson ,  Patricia Wood ,  Stephen Burton ,  Alan Quirk

发明人： Andrew Goodey ,  Darell Sleep ,  Hendrik Van Urk ,  Stephen Berezenko ,  John Woodrow ,  Richard Johnson ,  Patricia Wood ,  Stephen Burton ,  Alan Quirk

IPC分类号： C12P21/00

CPC分类号： C07K14/70571 ,  C07K14/765 ,  C07K2319/10

摘要： A process is provided for the preparation of albumin which has extremely low levels of or is essentially free of colorants, metal ions, human proteins, host proteins, fragments of albumin, polymers or aggregates of albumin and viruses, and which is essentially non-glycated, relatively high in free thiol and with an intact C-terminus. The process comprises passing albumin (preferably expressed and secreted by transformed yeast) through positive mode cation exchange and then positive mode anion exchange chromatography. Other steps may also be employed, for example ultrafiltration, gel permeation chromatography, affinity chromatography binding the albumin and affinity chromatography binding contaminants. Elution of albumin, with a compound having affinity for albumin, from a material having no specific affinity for albumin is also disclosed, as is removal of ammonium ions with a counter-ion.

摘要翻译： 提供了一种制备白蛋白的方法，其具有极低水平或基本上不含着色剂，金属离子，人蛋白质，宿主蛋白质，白蛋白片段，白蛋白和病毒的聚合物或聚集体，并且基本上未被糖化 ，游离硫醇相对较高，具有完整的C末端。 该方法包括使白蛋白（优选由转化的酵母表达和分泌）通过阳离子阳离子交换，然后进行阳性阴离子交换层析。 也可以采用其它步骤，例如超滤，凝胶渗透色谱法，结合白蛋白的亲和层析和亲和层析结合污染物。 还公开了从对白蛋白没有特异性亲和力的物质洗脱白蛋白和具有对白蛋白的亲和性的化合物，以及用抗衡离子除去铵离子。

公开(公告)号：US20050142636A1

公开(公告)日：2005-06-30

申请号：US10873504

申请日：2004-06-22

申请人： Andrew Goodey ,  Darell Sleep ,  Hendrik Van Urk ,  Stephen Berezenko ,  John Woodrow ,  Richard Johnson ,  Patricia Wood ,  Stephen Burton ,  Alan Quirk

发明人： Andrew Goodey ,  Darell Sleep ,  Hendrik Van Urk ,  Stephen Berezenko ,  John Woodrow ,  Richard Johnson ,  Patricia Wood ,  Stephen Burton ,  Alan Quirk

IPC分类号： C12P21/02 ,  A61K9/08 ,  A61K47/42 ,  A61P7/08 ,  A61P17/02 ,  C07K14/76 ,  C07K14/765 ,  C12N1/19 ,  C12N15/14 ,  C12N1/18

CPC分类号： C07K14/70571 ,  C07K14/765 ,  C07K2319/10

摘要： A process is provided for the preparation of albumin which has extremely low levels of or is essentially free of colorants, metal ions, human proteins, host proteins, fragments of albumin, polymers or aggregates of albumin and viruses, and which is essentially non-glycated, relatively high in free thiol and with an intact C-terminus. The process comprises passing albumin (preferably expressed and secreted by transformed yeast) through positive mode cation exchange and then positive mode anion exchange chromatography. Other steps may also be employed, for example ultrafiltration, gel permeation chromatography, affinity chromatography binding the albumin (for example using blue dyes) and affinity chromatography binding contaminants (for example using an aminophenylboronic acid resin). Elution of albumin, with a compound having affinity for albumin, from a material having no specific affinity for albumin is also disclosed, as is removal of ammonium ions with a counter-ion.

摘要翻译： 提供了一种制备白蛋白的方法，其具有极低水平或基本上不含着色剂，金属离子，人蛋白质，宿主蛋白质，白蛋白片段，白蛋白和病毒的聚合物或聚集体，并且基本上未被糖化 ，游离硫醇相对较高，具有完整的C末端。 该方法包括使白蛋白（优选由转化的酵母表达和分泌）通过阳离子阳离子交换，然后进行阳性阴离子交换层析。 还可以采用其他步骤，例如超滤，凝胶渗透色谱法，结合白蛋白的亲和层析（例如使用蓝色染料）和亲和层析结合污染物（例如使用氨基苯基硼酸树脂）。 还公开了从对白蛋白没有特异性亲和力的物质洗脱白蛋白和具有对白蛋白的亲和性的化合物，以及用抗衡离子除去铵离子。

公开(公告)号：USPP22653P2

公开(公告)日：2012-04-17

申请号：US13065116

申请日：2011-03-15

申请人： Stephen Burton

发明人： Stephen Burton

IPC分类号： A01H5/00

CPC分类号： A01H5/02

摘要： A new cultivar of Hebe, ‘Grace Kelly’, characterized by its large leaves that are variegated with greyed-green centers and distinct creamy white margins with a red-purple central vein, its young leaves that are tinged with yellow at the tips, its foliage that is resistant to leaf spot and its medium sized racemes that are red-purple in color.

摘要翻译： 一个新的品种“Heace”，“Grace Kelly”，其大叶子呈灰绿绿色的中心，并且具有紫红色中心静脉的不同的乳白色边缘，其年轻的叶子在尖端呈黄色， 叶片抗紫叶斑点和中等大小的总状花序，呈红紫色。

公开(公告)号：USPP21032P2

公开(公告)日：2010-06-01

申请号：US12322732

申请日：2009-02-06

申请人： Stephen Burton

发明人： Stephen Burton

IPC分类号： A01H5/00

CPC分类号： A01H5/00

摘要： A new cultivar of Coprosma, ‘Pina Colada’, characterized by its wavy, glossy yellow-gold leaves that intensify in winter to orange-red, its deep red-orange margins, and a compact growth habit with short branch internodes.

摘要翻译： Coprosma的新品种“Pina Colada”，其波浪形光泽的黄金叶子，冬天变得橙红色，深红橙色的边缘，以及具有短枝节间的紧密生长习性。

公开(公告)号：USPP19388P2

公开(公告)日：2008-10-28

申请号：US11823592

申请日：2007-06-28

申请人： Stephen Burton

发明人： Stephen Burton

IPC分类号： A01H5/00

CPC分类号： A01H6/42 ,  A01H5/02

摘要： A new and distinct cultivar of Geranium plant named ‘Thunder Cloud’, characterized by its white-colored flowers having pink-colored venation, dark purple-colored foliage, and rosette growth habit.

摘要翻译： 一个新的和独特的天竺葵植物名为“雷云”，其白色花朵有粉红色的脉络，深紫色的树叶和玫瑰花的生长习性。

公开(公告)号：US20080148440P1

公开(公告)日：2008-06-19

申请号：US12011336

申请日：2008-01-25

申请人： Stephen Burton

发明人： Stephen Burton

IPC分类号： A01H5/00

CPC分类号： A01H5/02

摘要： A new cultivar of Hebe hybrid origin, Hebe ‘Sunset Boulevard’, characterized by its abundant flower spikes of mauve pink flowers, dark green foliage, and resistance to powdery mildew.

摘要翻译： 河北“日落大道”新品种Hebe杂交起源，其丰富的淡紫色粉红色花朵的鲜花，深绿色的树叶和抗白粉病。

公开(公告)号：US20070063603A1

公开(公告)日：2007-03-22

申请号：US11601060

申请日：2006-11-17

申请人： Gregory Levine ,  Daniel Hilton ,  Michael Major ,  Stephen Burton ,  Scott Schroer ,  Peter Stultz

发明人： Gregory Levine ,  Daniel Hilton ,  Michael Major ,  Stephen Burton ,  Scott Schroer ,  Peter Stultz

IPC分类号： H02K3/24 ,  H02K11/00 ,  H02K5/10

CPC分类号： D06F37/304 ,  D06F37/206 ,  H02K11/33 ,  Y02B40/52

摘要： A front loading washing machine includes an integrated motor and controller assembly. In various embodiment, the controller is mounted directly to one of a pair of opposing endshields of the electric motor and the endshields are mounted directly to a stator of the motor. Additional embodiments include a rotor shaft of the motor having each of opposing ends supported within a bearing mounted within a respective one of the opposing endshields. In other embodiments, the controller can include an insulating shield positioned between a controller circuit board and the motor endshield to which the controller is mounted. The insulating shield providing electrical arcing protection, thermal insulation and/or electromagnetic insulation between the circuit board and the endshield.

摘要翻译： 前装式洗衣机包括集成电动机和控制器组件。 在各种实施例中，控制器直接安装在电动机的一对相对的末端之一中，并且末端罩直接安装在电动机的定子上。 另外的实施例包括电动机的转子轴，其每个相对的端部支撑在安装在相对的一个相对端盖内的轴承内。 在其他实施例中，控制器可以包括定位在控制器电路板和控制器所安装的电动机末端之间的绝缘屏蔽。 绝缘屏蔽层在电路板和端盖之间提供电弧保护，隔热和/或电磁绝缘。

公开(公告)号：USPP29827P2

公开(公告)日：2018-11-13

申请号：US15732626

申请日：2017-12-05

申请人： Stephen Burton

发明人： Stephen Burton

IPC分类号： A01H5/00

摘要： A new cultivar of Coprosma plant named ‘NGCOP8’ that is characterized by a compact habit, glossy leaves, young upper side leaves that are red in color with speckles of yellow-green, mature upper side leaves that are grey-green in color and resistance to leaf scorch.

公开(公告)号：USPP27223P3

公开(公告)日：2016-10-04

申请号：US14544340

申请日：2014-12-26

申请人： Stephen Burton

发明人： Stephen Burton

IPC分类号： A01H5/00

摘要： A new cultivar of Coprosma plant named ‘Scarlett 2’ that is characterized by a compact habit, glossy leaves, young leaves that are grey-purple and mature leaves that are brown with grey-red margins.

摘要翻译： Coprosma植物的新品种名为“Scarlett 2”，其特征是紧凑的习惯，光泽的叶子，青色的叶子是灰紫色和成熟的叶子，具有灰红色的边缘。

公开(公告)号：USPP18392P2

公开(公告)日：2008-01-01

申请号：US11452644

申请日：2006-06-14

申请人： Stephen Burton

发明人： Stephen Burton

IPC分类号： A01H5/00

CPC分类号： A01H5/00

摘要： A new cultivar of Coprosma plant named ‘Tequila Sunrise’ that is characterized by an upright and outwardly spreading habit, leaves that change from green and yellow in the spring to orange and green during the summer to burgundy and brown in the fall and moderate vigor.

摘要翻译： 一个名为“龙舌兰酒日出”的新品种“龙舌兰酒日出”，其特征是具有直立和向外扩散的习惯，夏天的绿色和黄色变成橙色和绿色，在秋天变得勃艮第和棕色，中度活力。