摘要:
An apparatus for wide-field functional imaging (WiFI) of tissue includes a spatially modulated reflectance/fluorescence imaging (SI) device capable of quantitative subsurface imaging across spatial scales, and a laser speckle imaging (LSI) device capable of quantitative subsurface imaging across spatial scales using integrated with the (SI) device. The SI device and LSI device are capable of independently providing quantitative measurement of tissue functional status.
摘要:
An apparatus for wide-field functional imaging (WIFI) of tissue includes a spatially modulated reflectance/fluorescence imaging (SI) device capable of quantitative subsurface imaging across spatial scales, and a laser speckle imaging (LSI) device capable of quantitative subsurface imaging across spatial scales using integrated with the (SI) device. The SI device and LSI device are capable of independently providing quantitative measurement of tissue functional status.
摘要:
A digital imaging system provides color information of an entire port wine stain or other skin condition with a single image in CIE L*a*b* color space (L*, a*) derived from RGB pixel data (R, G, B). Cross-polarization optics produce marked reduction in specularly reflected light in the images. A patient positioning device allows for repeatable positioning of the patient's head or body portion. The digital nature of the system provides a near real-time mapping of melanin and erythema or other skin chromophore metrics. The cross-polarized diffuse reflectance color digital imaging system obtains subsurface skin color information and acquisition of facial images in a reproducible fashion at a fixed distance from an illumination source at optimized angles of view depending on the region of interest being imaged.
摘要翻译:数字成像系统在从RGB像素数据(R,G,B)得到的CIE L * a * b *颜色空间(L *,a *)中提供具有单个图像的整个端口葡萄酒渍或其它皮肤状况的颜色信息, 。 交叉偏振光学在图像中产生镜面反射光的显着减少。 患者定位装置允许患者的头部或身体部分的可重复定位。 该系统的数字性质提供了近乎实时的黑色素和红斑或其他皮肤发色团指标的绘图。 交叉偏振漫反射彩色数字成像系统根据所成像的感兴趣区域以优化的视角从照明源以固定的距离以可再现的方式获得地下皮肤颜色信息和面部图像。
摘要:
The invention includes a noninvasive method for characterizing dental pulpal vitality of a tooth including the steps of irradiating the tooth with at least partially coherent light, and speckle imaging to provide quantitative feedback to an end user of pulpal blood flow in the tooth, and the tangible records made by such a method. The invention also includes an apparatus for noninvasively characterizing dental pulpal vitality of a tooth comprising a source of at least partially coherent light for irradiating the tooth characterized by a speckle pattern, optics for directing the at least partially coherent light onto the tooth, including a corresponding pulpal cavity within the tooth, a detector for detecting transmission of the at least partially coherent light through the tooth, and a processor coupled to the detector speckle imaging to provide a quantitative feedback of pulpal blood flow in the tooth.
摘要:
A digital imaging system provides color information of an entire port wine stain or other skin condition with a single image in CIE L*a*b* color space (L*, a*) derived from RGB pixel data (R, G, B). Cross-polarization optics produce marked reduction in specularly reflected light in the images. A patient positioning device allows for repeatable positioning of the patient's head or body portion. The digital nature of the system provides a near real-time mapping of melanin and erythema or other skin chromophore metrics. The cross-polarized diffuse reflectance color digital imaging system obtains subsurface skin color information and acquisition of facial images in a reproducible fashion at a fixed distance from an illumination source at optimized angles of view depending on the region of interest being imaged.
摘要翻译:数字成像系统在从RGB像素数据(R,G,B)得到的CIE L * a * b *颜色空间(L *,a *)中提供具有单个图像的整个端口葡萄酒渍或其它皮肤状况的颜色信息, 。 交叉偏振光学在图像中产生镜面反射光的显着减少。 患者定位装置允许患者的头部或身体部分的可重复定位。 该系统的数字性质提供了近乎实时的黑色素和红斑或其他皮肤发色团指标的绘图。 交叉偏振漫反射彩色数字成像系统根据所成像的感兴趣区域以优化的视角从照明源以固定的距离以可再现的方式获得地下皮肤颜色信息和面部图像。
摘要:
This disclosure relates generally to methods for increasing the permeability of tissue. More particularly, it relates to increasing the permeability of a skin tissue or other epidermal tissue to promote delivery of active substances locally and systemically, and to control the delivery of active substances topically.