公开(公告)号：US11987904B2

公开(公告)日：2024-05-21

申请号：US16081635

申请日：2017-03-02

申请人： Aptamer Group Limited

发明人： Shuji Ikeda ,  Shozo Fujita ,  Tsuyoshi Fujihara

IPC分类号： C40B40/06 ,  C12N15/10 ,  C12N15/115 ,  C40B40/08

CPC分类号： C40B40/08 ,  C12N15/1093 ,  C12N15/115 ,  C12N2310/16 ,  C12N2310/52 ,  C12N2320/11 ,  C12N2330/31

摘要： Oligonucleotide constructs are described, each comprising a functional element and a coding element, wherein the functional element comprises a functional sequence, the functional sequence comprising a sequence of nucleotides in which one or more, or each, nucleotide is modified and the coding element comprises a coding sequence, the coding sequence comprising a sequence of nucleotides which do not contain the modifications of the functional sequence, wherein the coding sequence encodes the sequence structure of the functional sequence.