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公开(公告)号：US09433640B2
公开(公告)日：2016-09-06
申请号：US15052186
申请日：2016-02-24
申请人： Ardelyx, Inc.
发明人： Dominique Charmot , James P. Davidson , Fangling Lin , Jeffrey W. Jacobs , Natalia Blinova , Eric Labonte , Ingrid Langsetmo , Robert C. Blanks
IPC分类号： A61K31/795 , B01J39/20 , A61K9/14 , A61K9/16
CPC分类号： A61K31/795 , A61K9/0056 , A61K9/0095 , A61K9/10 , A61K9/14 , A61K9/145 , A61K9/16 , A61K47/12 , B01J39/20 , C08F212/14
摘要： The present invention is directed to compositions and methods of removing potassium or treating hyperkalemia by administering pharmaceutical compositions of cation exchange polymers with low crosslinking for improved potassium excretion and for beneficial physical properties to increase patient compliance.
摘要翻译： 本发明涉及通过施用具有低交联性的阳离子交换聚合物的药物组合物来去除钾或治疗高钾血症的组合物和方法，用于改善钾排泄和有益的物理性质以增加患者依从性。
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公开(公告)号：US20180064751A1
公开(公告)日：2018-03-08
申请号：US15487967
申请日：2017-04-14
申请人： Ardelyx, Inc.
发明人： Dominique Charmot , James P. Davidson , Fangling Lin , Jeffrey W. Jacobs , Natalia Blinova , Eric Labonte , Ingrid Langsetmo , Robert C. Blanks
IPC分类号： A61K31/795 , A61K31/745 , C08F8/44 , A61K9/00 , A61K47/12 , A61K47/26 , A61K9/10 , C08F8/36 , C08F220/22 , A61K9/16 , C08F257/00 , B01J39/20 , C08F212/08 , C08F212/36 , C08F212/14
CPC分类号： A61K31/795 , A61K9/0053 , A61K9/0056 , A61K9/0095 , A61K9/10 , A61K9/1611 , A61K9/1617 , A61K9/1623 , A61K9/1652 , A61K31/745 , A61K47/12 , A61K47/26 , B01J39/20 , C08F8/36 , C08F8/44 , C08F212/14 , C08F220/22 , C08F257/00 , C08F2800/10 , C08F212/08 , C08F212/36 , C08F236/20 , C08F8/12 , C08F222/20
摘要： The present invention is directed to compositions and methods of removing potassium or treating hyperkalemia by administering pharmaceutical compositions of cation exchange polymers with low crosslinking for improved potassium excretion and for beneficial physical properties to increase patient compliance.
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公开(公告)号：US09549947B2
公开(公告)日：2017-01-24
申请号：US15052193
申请日：2016-02-24
申请人： Ardelyx, Inc.
发明人： Dominique Charmot , James P. Davidson , Fangling Lin , Jeffrey W. Jacobs , Natalia Blinova , Eric Labonte , Ingrid Langsetmo , Robert C. Blanks
CPC分类号： A61K31/795 , A61K9/0056 , A61K9/0095 , A61K9/10 , A61K9/14 , A61K9/145 , A61K9/16 , A61K47/12 , B01J39/20 , C08F212/14
摘要： The present invention is directed to compositions and methods of removing potassium or treating hyperkalemia by administering pharmaceutical compositions of cation exchange polymers with low crosslinking for improved potassium excretion and for beneficial physical properties to increase patient compliance.
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公开(公告)号：US09545425B2
公开(公告)日：2017-01-17
申请号：US15052190
申请日：2016-02-24
申请人： Ardelyx, Inc.
发明人： Dominique Charmot , James P. Davidson , Fangling Lin , Jeffrey W. Jacobs , Natalia Blinova , Eric Labonte , Ingrid Langsetmo , Robert C. Blanks
CPC分类号： A61K31/795 , A61K9/0056 , A61K9/0095 , A61K9/10 , A61K9/14 , A61K9/145 , A61K9/16 , A61K47/12 , B01J39/20 , C08F212/14
摘要： The present invention is directed to compositions and methods of removing potassium or treating hyperkalemia by administering pharmaceutical compositions of cation exchange polymers with low crosslinking for improved potassium excretion and for beneficial physical properties to increase patient compliance.
摘要翻译： 本发明涉及通过施用具有低交联性的阳离子交换聚合物的药物组合物来去除钾或治疗高钾血症的组合物和方法，用于改善钾排泄和有益的物理性质以增加患者依从性。
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公开(公告)号：US20160346318A1
公开(公告)日：2016-12-01
申请号：US14912682
申请日：2015-12-22
申请人： ARDELYX, INC.
发明人： Dominique Charmot , James P. Davidson , Fangling Lin , Jeffrey W. Jacobs , Natalia Blinova , Eric Labonte , Ingrid Langsetmo , Robert C. Blanks
IPC分类号： A61K31/795 , B01J39/20 , C08F257/00 , A61K9/16 , A61K9/00
CPC分类号： A61K31/795 , A61K9/0053 , A61K9/0056 , A61K9/0095 , A61K9/10 , A61K9/1611 , A61K9/1617 , A61K9/1623 , A61K9/1652 , A61K31/745 , A61K47/12 , A61K47/26 , B01J39/20 , C08F8/36 , C08F8/44 , C08F212/14 , C08F220/22 , C08F257/00 , C08F2800/10 , C08F212/08 , C08F212/36 , C08F236/20 , C08F8/12 , C08F222/20
摘要： The present invention is directed to compositions and methods of removing potassium or treating hyperkalemia by administering pharmaceutical compositions of cation exchange polymers with low crosslinking for improved potassium excretion and for beneficial physical properties to increase patient compliance.
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公开(公告)号：US09867848B2
公开(公告)日：2018-01-16
申请号：US15472936
申请日：2017-03-29
申请人： Ardelyx, Inc.
发明人： Dominique Charmot , James P. Davidson , Fangling Lin , Jeffrey W. Jacobs , Natalia Blinova , Eric Labonte , Ingrid Langsetmo , Robert C. Blanks
IPC分类号： A61K31/795 , A61K9/14 , B01J39/20 , C08F212/14
CPC分类号： A61K31/795 , A61K9/0056 , A61K9/0095 , A61K9/10 , A61K9/14 , A61K9/145 , A61K9/16 , A61K47/12 , B01J39/20 , C08F212/14
摘要： The present invention is directed to compositions and methods of removing potassium or treating hyperkalemia by administering pharmaceutical compositions of cation exchange polymers with low crosslinking for improved potassium excretion and for beneficial physical properties to increase patient compliance.
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公开(公告)号：US20170196903A1
公开(公告)日：2017-07-13
申请号：US15472936
申请日：2017-03-29
申请人： Ardelyx, Inc.
发明人： Dominique Charmot , James P. Davidson , Fangling Lin , Jeffrey W. Jacobs , Natalia Blinova , Eric Labonte , Ingrid Langsetmo , Robert C. Blanks
IPC分类号： A61K31/795 , B01J39/20 , C08F212/14 , A61K9/14
CPC分类号： A61K31/795 , A61K9/0056 , A61K9/0095 , A61K9/10 , A61K9/14 , A61K9/145 , A61K9/16 , A61K47/12 , B01J39/20 , C08F212/14
摘要： The present invention is directed to compositions and methods of removing potassium or treating hyperkalemia by administering pharmaceutical compositions of cation exchange polymers with low crosslinking for improved potassium excretion and for beneficial physical properties to increase patient compliance.
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公开(公告)号：US20170173072A1
公开(公告)日：2017-06-22
申请号：US15223798
申请日：2016-07-29
申请人： Ardelyx, Inc.
发明人： Dominique Charmot , James P. Davidson , Fangling Lin , Jeffrey W. Jacobs , Natalia Blinova , Eric Labonte , Ingrid Langsetmo , Robert C. Blanks
IPC分类号： A61K31/795 , A61K9/14 , A61K9/00
CPC分类号： A61K31/795 , A61K9/0056 , A61K9/0095 , A61K9/10 , A61K9/14 , A61K9/145 , A61K9/16 , A61K47/12 , B01J39/20 , C08F212/14
摘要： The present invention is directed to compositions and methods of removing potassium or treating hyperkalemia by administering pharmaceutical compositions of cation exchange polymers with low crosslinking for improved potassium excretion and for beneficial physical properties to increase patient compliance.
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公开(公告)号：US09655921B2
公开(公告)日：2017-05-23
申请号：US14912682
申请日：2015-12-22
申请人： Ardelyx, Inc.
发明人： Dominique Charmot , James P. Davidson , Fangling Lin , Jeffrey W. Jacobs , Natalia Blinova , Eric Labonte , Ingrid Langsetmo , Robert C. Blanks
IPC分类号： A61K31/795 , A61K9/00 , A61K47/12 , A61K47/26 , A61K9/10 , A61K31/745 , C08F8/36 , C08F8/44 , C08F220/22 , A61K9/16 , B01J39/20 , C08F257/00
CPC分类号： A61K31/795 , A61K9/0053 , A61K9/0056 , A61K9/0095 , A61K9/10 , A61K9/1611 , A61K9/1617 , A61K9/1623 , A61K9/1652 , A61K31/745 , A61K47/12 , A61K47/26 , B01J39/20 , C08F8/36 , C08F8/44 , C08F212/14 , C08F220/22 , C08F257/00 , C08F2800/10 , C08F212/08 , C08F212/36 , C08F236/20 , C08F8/12 , C08F222/20
摘要： The present invention is directed to compositions and methods of removing potassium or treating hyperkalemia by administering pharmaceutical compositions of cation exchange polymers with low crosslinking for improved potassium excretion and for beneficial physical properties to increase patient compliance.
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公开(公告)号：US20160175345A1
公开(公告)日：2016-06-23
申请号：US15052190
申请日：2016-02-24
申请人： Ardelyx, Inc.
发明人： Dominique Charmot , James P. Davidson , Fangling Lin , Jeffrey W. Jacobs , Natalia Blinova , Eric Labonte , Ingrid Langsetmo , Robert C. Blanks
IPC分类号： A61K31/795 , A61K9/14
CPC分类号： A61K31/795 , A61K9/0056 , A61K9/0095 , A61K9/10 , A61K9/14 , A61K9/145 , A61K9/16 , A61K47/12 , B01J39/20 , C08F212/14
摘要： The present invention is directed to compositions and methods of removing potassium or treating hyperkalemia by administering pharmaceutical compositions of cation exchange polymers with low crosslinking for improved potassium excretion and for beneficial physical properties to increase patient compliance.
摘要翻译： 本发明涉及通过施用具有低交联性的阳离子交换聚合物的药物组合物来去除钾或治疗高钾血症的组合物和方法，用于改善钾排泄和有益的物理性质以增加患者依从性。
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