公开(公告)号：US20220128547A1

公开(公告)日：2022-04-28

申请号：US17337274

申请日：2021-06-02

申请人： Arizona Board of Regents, a body corporate of the State of Arizona, acting for and on behalf of Ariz ,  Engineering Arts LLC

发明人： Peter Wiktor ,  Joshua Labaer ,  Peter Kahn ,  Bharath Takulapalli ,  Ji Qiu ,  Al Brunner ,  Mitch Magee

IPC分类号： G01N33/543 ,  B01J19/00 ,  C40B50/14 ,  C40B60/12 ,  G01N33/68 ,  C12N15/10

摘要： Biomolecule arrays on a substrate are described which contain a plurality of biomolecules, such as coding nucleic acids and/or isolated polypeptides, at a plurality of discrete, isolated, locations. The arrays can be used, for example, in high throughput genomics and proteomics for specific uses including, but not limited molecular diagnostics for early detection, diagnosis, treatment, prognosis, monitoring clinical response, and protein crystallography.

公开(公告)号：US20180267029A1

公开(公告)日：2018-09-20

申请号：US15938575

申请日：2018-03-28

申请人： Arizona Board of Regents, a body corporate of the State of Arizona, acting for and on behalf of Ariz ,  Engineering Arts LLC

发明人： Peter Wiktor ,  Joshua Labaer ,  Peter Kahn ,  Bharath Takulapalli ,  Ji Qiu ,  Al Brunner ,  Mitch Magee

IPC分类号： G01N33/543 ,  G01N33/68 ,  C12N15/10 ,  C40B60/12 ,  C40B50/14 ,  B01J19/00

CPC分类号： G01N33/543 ,  B01J19/0046 ,  B01J2219/00317 ,  B01J2219/00596 ,  B01J2219/00608 ,  B01J2219/00612 ,  B01J2219/00621 ,  B01J2219/00626 ,  B01J2219/00637 ,  B01J2219/00659 ,  B01J2219/00722 ,  B01J2219/00725 ,  C12N15/1079 ,  C40B50/14 ,  C40B60/12 ,  G01N33/6845

摘要： Biomolecule arrays on a substrate are described which contain a plurality of biomolecules, such as coding nucleic acids and/or isolated polypeptides, at a plurality of discrete, isolated, locations. The arrays can be used, for example, in high throughput genomics and proteomics for specific uses including, but not limited molecular diagnostics for early detection, diagnosis, treatment, prognosis, monitoring clinical response, and protein crystallography.

公开(公告)号：US20140371091A1

公开(公告)日：2014-12-18

申请号：US14345032

申请日：2012-10-24

申请人： Arizona Board of Regents, a body corporate of the state of Arizona, acting for and on behalf of ,  Engineering Arts LLC

发明人： Peter Wiktor ,  Joshua Labaer ,  Peter Kahn ,  Bharath Takulapalli ,  Ji Qiu ,  Al Brunner ,  Mitch Magee

IPC分类号： G01N33/543

CPC分类号： G01N33/543 ,  B01J19/0046 ,  B01J2219/00317 ,  B01J2219/00596 ,  B01J2219/00608 ,  B01J2219/00612 ,  B01J2219/00621 ,  B01J2219/00626 ,  B01J2219/00637 ,  B01J2219/00659 ,  B01J2219/00722 ,  B01J2219/00725 ,  C12N15/1079 ,  C40B50/14 ,  C40B60/12 ,  G01N33/6845

摘要： Biomolecule arrays on a substrate are described which contain a plurality of biomolecules, such as coding nucleic acids and/or isolated polypeptides, at a plurality of discrete, isolated, locations. The arrays can be used, for example, in high throughput genomics and proteomics for specific uses including, but not limited molecular diagnostics for early detection, diagnosis, treatment, prognosis, monitoring clinical response, and protein crystallography.

摘要翻译： 描述了在多个离散的，隔离的位置上含有多个生物分子，例如编码核酸和/或分离的多肽的底物上的生物分子阵列。 阵列可用于例如用于特定用途的高通量基因组学和蛋白质组学，包括但不限于用于早期检测，诊断，治疗，预后，监测临床反应和蛋白质晶体学的分子诊断。