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1.发明申请ANTIBODIES DIRECTED AGAINST AMYLOID-BETA PEPTIDE AND METHODS USING SAME 有权针对AMYLOID-BETA肽的抗体和使用其的方法公开(公告)号：US20120269805A1
公开(公告)日：2012-10-25
申请号：US13542485
申请日：2012-07-05
申请人： Arnon Rosenthal , Jaume Pons , Wei-Hsien Ho , Jan Markus Grimm
发明人： Arnon Rosenthal , Jaume Pons , Wei-Hsien Ho , Jan Markus Grimm
IPC分类号： A61K39/395 , A61P25/28
CPC分类号： C07K16/18 , A61K39/00 , A61K2039/505 , C07K16/00 , C07K2317/21 , C07K2317/24 , C07K2317/41 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/92
摘要： Monoclonal antibody 9TL and antibodies derived from 9TL directed against amyloid-beta peptide and methods of using same for diagnosing and treatment of Alzheimer's disease and Aβ peptide associated diseases are described. Methods of using antibodies directed against amyloid-beta peptide having impaired effector function for treatment of Alzheimer's disease and Aβ peptide associated diseases are also described.
摘要翻译： 单克隆抗体9TL和衍生自针对淀粉样蛋白-β肽的9TL的抗体及其用于诊断和治疗阿尔茨海默病和A＆bgr的方法; 描述了肽相关疾病。 使用针对具有受损效应物功能的淀粉样蛋白-β肽的抗体治疗阿尔茨海默病和A＆Bgr的方法; 还描述了肽相关疾病。
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2.发明授权公开(公告)号：US08268593B2
公开(公告)日：2012-09-18
申请号：US12754579
申请日：2010-04-05
申请人： Arnon Rosenthal , Jaume Pons , Wei-Hsien Ho , Jan Markus Grimm
发明人： Arnon Rosenthal , Jaume Pons , Wei-Hsien Ho , Jan Markus Grimm
CPC分类号： C07K16/18 , A61K39/00 , A61K2039/505 , C07K16/00 , C07K2317/21 , C07K2317/24 , C07K2317/41 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/92
摘要： Monoclonal antibody 9TL and antibodies derived from 9TL directed against amyloid-beta peptide and methods of using same for diagnosing and treatment of Alzheimer's disease and Aβ peptide associated diseases are described. Methods of using antibodies directed against amyloid-beta peptide having impaired effector function for treatment of Alzheimer's disease and Aβ peptide associated diseases are also described.
摘要翻译： 单克隆抗体9TL和衍生自针对淀粉样蛋白-β肽的9TL的抗体及其用于诊断和治疗阿尔茨海默病和A＆bgr的方法; 描述了肽相关疾病。 使用针对具有受损效应物功能的淀粉样蛋白-β肽的抗体治疗阿尔茨海默病和A＆Bgr的方法; 还描述了肽相关疾病。
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公开(公告)号：US07927594B2
公开(公告)日：2011-04-19
申请号：US11194989
申请日：2005-08-01
申请人： Arnon Rosenthal , Jaume Pons , Wei-Hsien Ho , Jan Markus Grimm
发明人： Arnon Rosenthal , Jaume Pons , Wei-Hsien Ho , Jan Markus Grimm
IPC分类号： A61K39/395 , C12P21/08
CPC分类号： C07K16/18 , A61K39/00 , A61K2039/505 , C07K16/00 , C07K2317/21 , C07K2317/24 , C07K2317/41 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/92
摘要： Monoclonal antibody 9TL and antibodies derived from 9TL directed against amyloid-beta peptide and methods of using same for diagnosing and treatment of Alzheimer's disease and Aβ peptide associated diseases are described. Methods of using antibodies directed against amyloid-beta peptide having impaired effector function for treatment of Alzheimer's disease and Aβ peptide associated diseases are also described.
摘要翻译： 单克隆抗体9TL和衍生自针对淀粉样蛋白-β肽的9TL的抗体及其用于诊断和治疗阿尔茨海默病和A＆bgr的方法; 描述了肽相关疾病。 使用针对具有受损效应物功能的淀粉样蛋白-β肽的抗体治疗阿尔茨海默病和A＆Bgr的方法; 还描述了肽相关疾病。
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公开(公告)号：US20060057702A1
公开(公告)日：2006-03-16
申请号：US11195207
申请日：2005-08-01
申请人： Arnon Rosenthal , Jaume Pons , Wei-Hsien Ho , Jan Grimm
发明人： Arnon Rosenthal , Jaume Pons , Wei-Hsien Ho , Jan Grimm
IPC分类号： C12N1/20
CPC分类号： C07K16/18 , A61K39/00 , A61K2039/505 , C07K16/00 , C07K2317/21 , C07K2317/24 , C07K2317/41 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/92
摘要： Monoclonal antibody 9TL and antibodies derived from 9TL directed against amyloid-beta peptide and methods of using same for diagnosing and treatment of Alzheimer's disease and Aβ peptide associated diseases are described. Methods of using antibodies directed against amyloid-beta peptide having impaired effector function for treatment of Alzheimer's disease and Aβ peptide associated diseases are also described.
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公开(公告)号：US20060057701A1
公开(公告)日：2006-03-16
申请号：US11194989
申请日：2005-08-01
申请人： Arnon Rosenthal , Jaume Pons , Wei-Hsien Ho , Jan Grimm
发明人： Arnon Rosenthal , Jaume Pons , Wei-Hsien Ho , Jan Grimm
IPC分类号： C12N1/20
CPC分类号： C07K16/18 , A61K39/00 , A61K2039/505 , C07K16/00 , C07K2317/21 , C07K2317/24 , C07K2317/41 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/92
摘要： Monoclonal antibody 9TL and antibodies derived from 9TL directed against amyloid-beta peptide and methods of using same for diagnosing and treatment of Alzheimer's disease and Aβ peptide associated diseases are described. Methods of using antibodies directed against amyloid-beta peptide having impaired effector function for treatment of Alzheimer's disease and Aβ peptide associated diseases are also described.
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6.发明授权公开(公告)号：US08425905B2
公开(公告)日：2013-04-23
申请号：US13542485
申请日：2012-07-05
申请人： Arnon Rosenthal , Jaume Pons , Wei-Hsien Ho , Jan Markus Grimm
发明人： Arnon Rosenthal , Jaume Pons , Wei-Hsien Ho , Jan Markus Grimm
IPC分类号： A61K39/395
CPC分类号： C07K16/18 , A61K39/00 , A61K2039/505 , C07K16/00 , C07K2317/21 , C07K2317/24 , C07K2317/41 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/92
摘要： Monoclonal antibody 9TL and antibodies derived from 9TL directed against amyloid-beta peptide and methods of using same for diagnosing and treatment of Alzheimer's disease and Aβ peptide associated diseases are described. Methods of using antibodies directed against amyloid-beta peptide having impaired effector function for treatment of Alzheimer's disease and Aβ peptide associated diseases are also described.
摘要翻译： 描述单克隆抗体9TL和衍生自针对淀粉样蛋白-β肽的9TL的抗体及其用于诊断和治疗阿尔茨海默病和Aβ肽相关疾病的方法。 还描述了使用针对具有受损效应物功能的淀粉样蛋白-β肽的抗体治疗阿尔茨海默病和Aβ肽相关疾病的方法。
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7.发明申请公开(公告)号：US20060292152A1
公开(公告)日：2006-12-28
申请号：US11413817
申请日：2006-04-28
申请人： Arnon Rosenthal , Jaume Pons , Wei-Hsien Ho
发明人： Arnon Rosenthal , Jaume Pons , Wei-Hsien Ho
IPC分类号： A61K39/395 , C07H21/04 , C12P21/06 , C12N5/06 , C07K16/40
CPC分类号： C07K16/18 , A61K2039/505 , C07K16/28 , C07K2317/14 , C07K2317/21 , C07K2317/41 , C07K2317/52 , C07K2317/522 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/92
摘要： Antibodies directed to the C-terminal side of β-amyloid peptide and methods of using these antibodies for diagnosing and treatment of Alzheimer's disease and Aβ peptide associated diseases are described.
摘要翻译： 描述了针对β-淀粉样蛋白肽的C末端侧的抗体以及使用这些抗体诊断和治疗阿尔茨海默病和Aβ肽相关疾病的方法。
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8.发明授权公开(公告)号：US07807165B2
公开(公告)日：2010-10-05
申请号：US11195207
申请日：2005-08-01
申请人： Arnon Rosenthal , Jaume Pons , Wei-Hsien Ho , Jan Markus Grimm
发明人： Arnon Rosenthal , Jaume Pons , Wei-Hsien Ho , Jan Markus Grimm
IPC分类号： A61K39/395 , A61K39/00
CPC分类号： C07K16/18 , A61K39/00 , A61K2039/505 , C07K16/00 , C07K2317/21 , C07K2317/24 , C07K2317/41 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/92
摘要： Monoclonal antibody 9TL and antibodies derived from 9TL directed against amyloid-beta peptide and methods of using same for diagnosing and treatment of Alzheimer's disease and Aβ peptide associated diseases are described. Methods of using antibodies directed against amyloid-beta peptide having impaired effector function for treatment of Alzheimer's disease and Aβ peptide associated diseases are also described.
摘要翻译： 单克隆抗体9TL和衍生自针对淀粉样蛋白-β肽的9TL的抗体及其用于诊断和治疗阿尔茨海默病和A＆bgr的方法; 描述了肽相关疾病。 使用针对具有受损效应物功能的淀粉样蛋白-β肽的抗体治疗阿尔茨海默病和A＆Bgr的方法; 还描述了肽相关疾病。
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9.发明授权公开(公告)号：US08398978B2
公开(公告)日：2013-03-19
申请号：US12724343
申请日：2010-03-15
申请人： Arnon Rosenthal , Jaume Pons , Wei-Hsien Ho
发明人： Arnon Rosenthal , Jaume Pons , Wei-Hsien Ho
IPC分类号： A61K39/00
CPC分类号： C07K16/18 , A61K2039/505 , C07K16/28 , C07K2317/14 , C07K2317/21 , C07K2317/41 , C07K2317/52 , C07K2317/522 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/92
摘要： Methods of using antibodies directed to the C-terminal side of β-amyloid peptide for diagnosing and treatment of Alzheimer's disease and Aβ peptide associated diseases are described.
摘要翻译： 使用针对β-淀粉状蛋白肽C末端侧的抗体来诊断和治疗阿尔茨海默病和A＆bgr的方法; 描述了肽相关疾病。
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10.发明申请ANTIBODIES DIRECTED AGAINST AMYLOID-BETA PEPTIDE AND METHODS USING SAME 有权针对AMYLOID-BETA肽的抗体和使用其的方法公开(公告)号：US20110044985A1
公开(公告)日：2011-02-24
申请号：US12724343
申请日：2010-03-15
申请人： Arnon Rosenthal , Jaume Pons , Wei-Hsien Ho
发明人： Arnon Rosenthal , Jaume Pons , Wei-Hsien Ho
IPC分类号： A61K39/395 , A61P25/28 , A61P25/16
CPC分类号： C07K16/18 , A61K2039/505 , C07K16/28 , C07K2317/14 , C07K2317/21 , C07K2317/41 , C07K2317/52 , C07K2317/522 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/92
摘要： Methods of using antibodies directed to the C-terminal side of β-amyloid peptide for diagnosing and treatment of Alzheimer's disease and Aβ peptide associated diseases are described.
摘要翻译： 使用针对β-淀粉状蛋白肽C末端侧的抗体来诊断和治疗阿尔茨海默病和A＆bgr的方法; 描述了肽相关疾病。
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