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公开(公告)号：US20080262333A1
公开(公告)日：2008-10-23
申请号：US12130091
申请日：2008-05-30
IPC分类号： A61B5/145
CPC分类号： A61B5/1495 , A61B5/14532 , A61B5/743 , A61B2560/0223 , G06F19/00 , G06F19/3456
摘要： Metabolism diseases are evaluated by using a sensor to measure concentration of a medically significant analyte in a human or animal body fluid. The measurement data are correlated with the concentration of a medically significant analyte in body fluid over a time period of at least eight hours. An analytical facility analyzes time intervals within the time period to determine a stability parameter that characterizes the analyte concentration dynamics of change. The analytical facility further analyzes the stability parameters to determine disease-related particularities of metabolism.
摘要翻译： 通过使用传感器来测量人体或动物体液中医学上重要的分析物的浓度来评估代谢疾病。 在至少8小时的时间内，测量数据与体液中医学上重要的分析物的浓度相关。 分析设备分析时间段内的时间间隔，以确定表征变化的分析物浓度动力学的稳定性参数。 分析设备进一步分析稳定性参数，以确定与疾病相关的新陈代谢特征。
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公开(公告)号：US08734347B2
公开(公告)日：2014-05-27
申请号：US12130091
申请日：2008-05-30
CPC分类号： A61B5/1495 , A61B5/14532 , A61B5/743 , A61B2560/0223 , G06F19/00 , G06F19/3456
摘要： Metabolism diseases are evaluated by using a sensor to measure concentration of a medically significant analyte in a human or animal body fluid. The measurement data are correlated with the concentration of a medically significant analyte in body fluid over a time period of at least eight hours. An analytical facility analyzes time intervals within the time period to determine a stability parameter that characterizes the analyte concentration dynamics of change. The analytical facility further analyzes the stability parameters to determine disease-related particularities of metabolism.
摘要翻译： 通过使用传感器来测量人体或动物体液中医学上重要的分析物的浓度来评估代谢疾病。 在至少8小时的时间内，测量数据与体液中医学上重要的分析物的浓度相关。 分析设备分析时间段内的时间间隔，以确定表征变化的分析物浓度动力学的稳定性参数。 分析设备进一步分析稳定性参数，以确定与疾病相关的新陈代谢特征。
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3.发明申请METHOD FOR DETECTING A MALFUNCTION OF A SENSOR FOR MEASURING AN ANALYTE CONCENTRATION IN VIVO 审中-公开检测传感器功能的方法，用于测量体内分析仪浓度公开(公告)号：US20120249158A1
公开(公告)日：2012-10-04
申请号：US13440312
申请日：2012-04-05
IPC分类号： G01R31/02
CPC分类号： A61B5/1495 , A61B5/14532 , A61B5/1468 , A61B5/1486 , A61B5/7203 , A61B5/725 , A61B5/746
摘要： The invention relates to a method for detecting a malfunction of a sensor for measuring an analyte concentration in vivo, wherein a series of measurement signals is produced by means of the sensor, and a value of a noise parameter is continually determined from the measuring signals, the noise parameter indicating how severely the measurement is impaired by interference signals. According to the invention, continually determined values of the noise parameter are used to determine how quickly the noise parameter changes, and the rate of change of the noise parameter is evaluated to detect a malfunction.
摘要翻译： 本发明涉及一种用于检测用于测量体内分析物浓度的传感器的故障的方法，其中通过传感器产生一系列测量信号，并根据测量信号连续地确定噪声参数的值， 噪声参数指示测量受到干扰信号的严重损害。 根据本发明，使用噪声参数的连续确定值来确定噪声参数变化的速度，并且评估噪声参数的变化率以检测故障。
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4.发明申请Stiochiometrically defined dye-labelled substances for measuring glomerular filtration rate, the production thereof and their use 审中-公开用于测量肾小球滤过率的生理学定义的染料标记物质，其生产及其用途公开(公告)号：US20070218563A1
公开(公告)日：2007-09-20
申请号：US11725951
申请日：2007-03-20
申请人： Johanes Pill , Uwe Kraemer , Norbert Gretz , Carsten Deus , Bernd Hagenbruch , Hans-Martin Kloetzer
发明人： Johanes Pill , Uwe Kraemer , Norbert Gretz , Carsten Deus , Bernd Hagenbruch , Hans-Martin Kloetzer
IPC分类号： G01N21/75
CPC分类号： A61K49/0052 , A61K49/0043
摘要： The invention concerns new chemical compounds that can be used as marker substances in renal diagnostics, their production and use, and renal diagnostic agents which contain them.
摘要翻译： 本发明涉及可用作肾脏诊断，其生产和使用中的标记物质以及含有它们的肾脏诊断剂的新化合物。
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