公开(公告)号：US20240358282A1

公开(公告)日：2024-10-31

申请号：US18618694

申请日：2024-03-27

申请人： Medtronic MiniMed, Inc.

发明人： Nor Akmaliza Rais ,  Chia-Hung Chiu ,  Meredith Hannah Buganski ,  Aishwarya Mahadevan

IPC分类号： A61B5/145 ,  A61B5/1468 ,  A61M5/172

CPC分类号： A61B5/14532 ,  A61B5/1468 ,  A61M5/1723

摘要： A device includes a glucose monitor comprising at least one sensor electrode configured to sense signals indicative of interstitial glucose level of a patient. The device also includes a memory and one or more processors implemented in circuitry and in communication with the memory. The one or more processors are configured to cause delivery of a cleaning electrical current to the at least one sensor electrode. The cleaning electrical current is one or more electrochemical cleaning pulses configured to at least partially remove, in vivo and from the sensor electrode, excipients associated with the delivery of a fluid that includes insulin.

公开(公告)号：US12127830B2

公开(公告)日：2024-10-29

申请号：US17880334

申请日：2022-08-03

申请人： DexCom, Inc.

发明人： Scott Alexander Fall ,  Patrick John Castagna ,  David A. Keller

IPC分类号： A61B5/145 ,  A61B5/00 ,  A61B5/1468 ,  A61B5/1486

CPC分类号： A61B5/14532 ,  A61B5/0024 ,  A61B5/1468 ,  A61B5/6833 ,  A61B5/0004 ,  A61B5/14503 ,  A61B5/14546 ,  A61B5/1486 ,  A61B2560/0406 ,  A61B2562/0295 ,  A61B2562/12 ,  A61B2562/14 ,  A61B2562/164 ,  A61B2562/18 ,  A61B2562/227

摘要： Various analyte sensing apparatuses and associated housings are provided. Some apparatuses comprise one or more caps. Some apparatuses comprise a two-part adhesive patch. Some apparatuses comprise one or more sensor bends configured to locate and/or hold a sensor in place during mounting. Some apparatuses utilize one or more dams and/or wells to retain epoxy for securing a sensor. Some apparatuses utilize a pocket and one or more adjacent areas and various transitions for preventing epoxy from wicking to undesired areas of the apparatus. Some apparatuses include heat-sealable thermoplastic elastomers for welding a cap to the apparatus. Related methods of fabricating such apparatuses and/or housings are also provided.

公开(公告)号：US12089899B2

公开(公告)日：2024-09-17

申请号：US18068984

申请日：2022-12-20

申请人： Boston Scientific Neuromodulation Corporation

发明人： Elizabeth M. Annoni ,  Bryan A. Clark ,  Dennis Zottola ,  Kyle H. Srivastava ,  Jonathan B. Shute

IPC分类号： A61B34/10 ,  A61N1/36 ,  A61B5/00 ,  A61B5/11 ,  A61B5/1468 ,  A61B5/318 ,  A61B5/369

CPC分类号： A61B34/10 ,  A61N1/36062 ,  A61B5/0075 ,  A61B5/11 ,  A61B5/1468 ,  A61B5/318 ,  A61B5/369

摘要： A virtual or augmented reality system is disclosed which is capable of both (i) evaluating prospective implantable neurostimulator patient candidates, and (ii) determining optimal stimulation settings for already-implanted neurostimulation patients. Physiological sensors are included with the system to provide objective measurements relevant to a patient's symptoms, such as pain in a Spinal Cord Stimulation (SCS) system. Such objective measurements are determined during the presentation of various virtual or augmented environments, and can be useful to determining which patients are suitable candidates to consider for implantation. Stimulation settings for already-implanted patients may be adjusted while presenting a virtual or augmented environment to the patient, with objective measurements being determined for each stimulation setting. Such objective measurements can then be used to determine optimal stimulation settings for the patient.

公开(公告)号：US12082930B2

公开(公告)日：2024-09-10

申请号：US17939067

申请日：2022-09-07

申请人： Medtronic MiniMed, Inc.

发明人： Peter Ajemba ,  Keith Nogueira ,  Jeffrey Nishida ,  Andy Y. Tsai

IPC分类号： A61B5/1495 ,  A61B5/00 ,  A61B5/0205 ,  A61B5/021 ,  A61B5/024 ,  A61B5/11 ,  A61B5/145 ,  A61B5/1455 ,  A61B5/1468 ,  A61B5/1486 ,  G01N27/02 ,  G06N5/022 ,  G16H20/17 ,  G16H40/40 ,  G16H50/30 ,  G16H50/70

CPC分类号： A61B5/1495 ,  A61B5/14532 ,  A61B5/1468 ,  A61B5/14865 ,  A61B5/6849 ,  A61B5/686 ,  G01N27/026 ,  G06N5/022 ,  G16H20/17 ,  G16H40/40 ,  G16H50/30 ,  G16H50/70 ,  A61B5/0075 ,  A61B5/02055 ,  A61B5/021 ,  A61B5/024 ,  A61B5/1118 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/7203 ,  A61B5/7221 ,  A61B5/7267 ,  A61B5/742 ,  A61B2505/07 ,  A61B2560/0223 ,  A61B2560/0252 ,  A61B2560/0257 ,  A61B2562/028 ,  A61B2562/029 ,  A61B2562/164

摘要： A continuous glucose monitoring system may utilize externally sourced information regarding the physiological state and ambient environment of its user for externally calibrating sensor glucose measurements. Externally sourced factory calibration information may be utilized, where the information is generated by comparing metrics obtained from the data used to generate the sensor's glucose sensing algorithm to similar data obtained from each batch of sensors to be used with the algorithm in the future. The output sensor glucose value of a glucose sensor may also be estimated by analytically optimizing input sensor signals to accurately correct for changes in sensitivity, run-in time, glucose current dips, and other variable sensor wear effects. Correction actors, fusion algorithms, EIS, and advanced ASICs may be used to implement the foregoing, thereby achieving the goal of improved accuracy and reliability without the need for blood-glucose calibration, and providing a calibration-free, or near calibration-free, sensor.

公开(公告)号：US20240268722A1

公开(公告)日：2024-08-15

申请号：US18624925

申请日：2024-04-02

申请人： Abbott Diabetes Care Inc.

发明人： Udo HOSS ,  Benjamin J. FELDMAN ,  Zenghe LIU ,  Hyun CHO ,  Benjamin M. RUSH

IPC分类号： A61B5/1473 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1468

CPC分类号： A61B5/1473 ,  A61B5/14532 ,  A61B5/7275 ,  A61B5/7405 ,  A61B5/742 ,  A61B5/7455 ,  A61B5/1451 ,  A61B5/1468 ,  A61B2560/0252 ,  A61B2560/0443

摘要： Method and system for determining real time analyte concentration including an analyte sensor having a portion in fluid contact with an interstitial fluid under a skin layer, an on-body electronics including a housing coupled to the analyte sensor and configured for positioning on the skin layer, the on-body electronics housing including a plurality of electrical contacts, on the housing; and a data analysis unit having a data analysis unit housing and a plurality of probes, on the housing. Each of the probes configured to electrically couple to a respective electrical contact when the data analysis unit is positioned in physical contact with the on-body electronics. The one or more signals on the probes correspond to one or more of a substantially real time monitored analyte concentration level (MACL), MACL over a predetermined time period, or a rate of change of the MACL, or combinations thereof, are provided.

公开(公告)号：US11967408B2

公开(公告)日：2024-04-23

申请号：US16273529

申请日：2019-02-12

申请人： Abbott Diabetes Care Inc.

发明人： R. Curtis Jennewine

IPC分类号： A61B5/1473 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1468 ,  A61M5/172 ,  G16H20/17 ,  G16H40/63 ,  G16H40/67

CPC分类号： G16H20/17 ,  A61B5/14532 ,  A61B5/1468 ,  A61B5/1473 ,  A61B5/4839 ,  A61B5/4848 ,  A61B5/7275 ,  A61B5/742 ,  A61M5/1723 ,  A61B5/0002 ,  A61M2230/201 ,  G16H40/63 ,  G16H40/67

摘要： Method and system for providing diabetes management and insulin therapy based on substantially real time glucose monitoring system is provided.

公开(公告)号：US11937927B2

公开(公告)日：2024-03-26

申请号：US16857107

申请日：2020-04-23

申请人： DexCom, Inc.

发明人： Peter C. Simpson ,  Robert J. Boock ,  Sebastian Bohm ,  James H. Brauker ,  Paul V. Neale

IPC分类号： A61B5/1486 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1468 ,  A61B5/1473

CPC分类号： A61B5/14865 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1468 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/6843 ,  A61B5/6848 ,  A61B5/6849 ,  A61B2560/0443 ,  A61B2562/04

摘要： A transcutaneous sensor device configured for continuously measuring analyte concentrations in a host is provided. In some embodiments, the transcutaneous sensor device 100 comprises an in vivo portion 160 configured for insertion under the skin 180 of the host and an ex vivo portion 170 configured to remain above the surface of the skin 180 of the host after sensor insertion of the in vivo portion. The in vivo portion may comprise a tissue piercing element 110 configured for piercing the skin 180 of the host and a sensor body 120 comprising a material or support member 130 that provides sufficient column strength to allow the sensor body to be pushable in a host tissue without substantial buckling. The ex vivo portion 170 may be configured to comprise (or operably connect to) a sensor electronics unit and may comprise a mounting unit 150. Also described here are various configurations of the sensor body and the tissue piercing element that may be used to protect the membrane of the sensor body.

公开(公告)号：US11883164B2

公开(公告)日：2024-01-30

申请号：US17574447

申请日：2022-01-12

申请人： Dexcom, Inc.

发明人： Apurv U Kamath ,  Jack Pryor ,  Paul V. Goode, Jr. ,  James H Brauker ,  Aarthi Mahalingam

IPC分类号： A61B5/1486 ,  A61B5/1473 ,  A61B5/1495 ,  A61B5/05 ,  A61B5/1468 ,  A61B5/145 ,  A61B5/00 ,  A61B5/15 ,  A61B17/34 ,  A61M5/172 ,  A61M5/158 ,  A61M5/142

CPC分类号： A61B5/14532 ,  A61B5/0002 ,  A61B5/0004 ,  A61B5/0031 ,  A61B5/05 ,  A61B5/1411 ,  A61B5/1451 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/1495 ,  A61B5/14503 ,  A61B5/14507 ,  A61B5/14514 ,  A61B5/14546 ,  A61B5/14735 ,  A61B5/14865 ,  A61B5/6801 ,  A61B5/6833 ,  A61B5/6848 ,  A61B5/6849 ,  A61B5/68335 ,  A61B5/72 ,  A61B17/3468 ,  A61B5/14 ,  A61B5/145 ,  A61B5/1468 ,  A61B5/150022 ,  A61B2017/3492 ,  A61B2560/0223 ,  A61B2560/045 ,  A61B2560/063 ,  A61B2562/18 ,  A61M5/14244 ,  A61M5/1723 ,  A61M2005/1585 ,  Y02A90/10

摘要： Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.

公开(公告)号：US11877857B2

公开(公告)日：2024-01-23

申请号：US16647293

申请日：2018-09-10

申请人： HOLOGIC, INC.

发明人： Estefania Alvarez

IPC分类号： A61B5/00 ,  G16H50/20 ,  G16H20/10 ,  A61B5/1468

CPC分类号： A61B5/4312 ,  A61B5/0022 ,  A61B5/1468 ,  A61B5/4842 ,  A61B5/4848 ,  A61B5/6867 ,  A61B5/74 ,  G16H20/10 ,  G16H50/20 ,  A61B2560/0219

摘要： Examples of the present disclosure describe systems and methods for the long-term, real-time active monitoring of a wireless implant. In aspects, a wireless biosensor may be implanted in a breast biopsy cavity. The biosensor may detect biochemical parameter data of the breast biopsy cavity and the human body. The biosensor may transmit the detected biochemical parameter data in real-time to a surveillance system wirelessly coupled to the biosensor. The surveillance system may then facilitate the evaluation of the biochemical parameter data. In examples, the evaluation may comprise detecting trends in a tumors microenvironment, monitoring the progress of a treatment, or adjusting a treatment to tailor a personalized treatment.

公开(公告)号：US20240008782A1

公开(公告)日：2024-01-11

申请号：US18252301

申请日：2021-11-09

申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

发明人： Ali Nsair

IPC分类号： A61B5/157 ,  A61B5/145 ,  A61B5/1455 ,  A61B5/1468 ,  A61B5/153

CPC分类号： A61B5/157 ,  A61B5/14535 ,  A61B5/1455 ,  A61B5/1468 ,  A61B5/153 ,  A61B2562/0233 ,  A61B2560/0223 ,  A61B2560/0443 ,  G01N33/4905

摘要： The present invention provides a smart syringe device that comprises an embedded impedance and optical sensors that allows for measuring activated clotting time (ACT) and Hemoglobin and Hematocrit (H&H) within the actual syringe without the need to disconnect the syringe from the patient.