公开(公告)号：US20220409596A1

公开(公告)日：2022-12-29

申请号：US17510797

申请日：2021-10-26

申请人： Aurobindo Pharma Ltd

发明人： Saravanan KANNUSAMY ,  Prabhakaran CHAKKIRALA ,  Nagaprasad VISHNUBHOTLA ,  Sivakumaran MEENAKSHISUNDERAM

IPC分类号： A61K31/4375 ,  A61K9/20

摘要： This present invention relates to pharmaceutical composition comprising Deutetrabenazine. The invention also relates to the methods of preparation of the composition having improved stability and dissolution profile and used for the treatment of chorea associated with Huntington disease and tardive dyskinesia.

公开(公告)号：US20200316043A1

公开(公告)日：2020-10-08

申请号：US16955566

申请日：2018-12-18

申请人： Aurobindo Pharma Ltd.

发明人： Amar nath BARIK ,  Vikas CHANDEL ,  Arvind GANNIMITA ,  Nagaprasad VISHNUBHOTLA ,  Sivakumaran MEENAKSHISUNDERAM

IPC分类号： A61K31/4422 ,  A61K9/00 ,  A61K47/44 ,  A61K47/24 ,  A61K47/10 ,  A61K47/12 ,  A61K9/107

摘要： The present invention relates to injectable oil in water pharmaceutical composition comprising effective amount of clevidipine or a pharmaceutically acceptable salt or ester as an active agent and process of preparation thereof. The invention also relates to the use of the emulsion in intravenous administration during surgery and postoperatively in hypertension and for short term treatment of hypertension when oral therapy is not feasible or desirable.

公开(公告)号：US20230390254A1

公开(公告)日：2023-12-07

申请号：US18204237

申请日：2023-05-31

申请人： Aurobindo Pharma Ltd

发明人： Saravanan KANNUSAMY ,  Koteswararao GUDE ,  Nagaprasad VISHNUBHOTLA ,  Sivakumaran MEENAKSHISUNDERAM

IPC分类号： A61K31/437 ,  A61K9/20

CPC分类号： A61K31/437 ,  A61K9/2027 ,  A61K9/2013 ,  A61K9/2009 ,  A61K9/2054 ,  A61K9/2018 ,  A61K9/2031

摘要： The present invention relates to a stable immediate release tablet compositions of Ubrogepant and one or more pharmaceutically acceptable excipients and a process for preparation thereof.

公开(公告)号：US20230053812A1

公开(公告)日：2023-02-23

申请号：US17875117

申请日：2022-07-27

申请人： Aurobindo Pharma Ltd

发明人： Saravanan KANNUSAMY ,  Prabhakaran CHAKKIRALA ,  Raghavendra Bharat GUNDA ,  Nagaprasad VISHNUBHOTLA ,  Meenakshisunderam SIVAKUMARAN

IPC分类号： A61K38/26 ,  A61K9/20 ,  A61K38/31 ,  A61K9/48 ,  A61K9/00 ,  A61K47/22 ,  A61K38/28 ,  A61K38/22 ,  A61K38/095 ,  A61K38/23 ,  A61K38/29 ,  A61K31/401

摘要： The invention relates to stable pharmaceutical formulation useful for the oral administration comprising a peptide or protein drug and a permeation enhancer. In particular, the invention relates to stabilized pharmaceutical formulations comprising GLP-1 receptor agonist such as Semaglutide and a permeation enhancer and its process for preparation.