公开(公告)号：US11766356B2

公开(公告)日：2023-09-26

申请号：US16979088

申请日：2019-03-08

Applicant: Avedro, Inc.

Inventor： Desmond Christopher Adler ,  Reza Zadno ,  Paul Bavier ,  David C. Iannetta ,  Jun Zhang

IPC: A61F9/008

CPC classification number: A61F9/008 ,  A61F2009/00872

Abstract: A micro-device for corneal cross-linking treatment includes a body including an outer portion and an inner portion. The outer portion is disposed about a periphery of the inner portion. The inner portion is shaped such that, when the body is positioned against a surface of an eye, the outer portion contacts the surface of the eye and the inner portion defines a chamber over a cornea of the eye. The micro-device includes an illumination system including a micro-optical element coupled to the body. The micro-optical element is configured to direct photoactivating light to the cornea of the eye when the body is positioned against the surface of the eye. The photoactivating light generates cross-linking activity with a cross-linking agent applied to the cornea.

公开(公告)号：US20210000646A1

公开(公告)日：2021-01-07

申请号：US16979088

申请日：2019-03-08

Applicant: Avedro, Inc.

Inventor： Desmond Christopher Adler ,  Reza Zadno ,  Paul Bavier ,  David C. Iannetta ,  Jun Zhang

IPC: A61F9/008

Abstract: A micro-device for corneal cross-linking treatment includes a body including an outer portion and an inner portion. The outer portion is disposed about a periphery of the inner portion. The inner portion is shaped such that, when the body is positioned against a surface of an eye, the outer portion contacts the surface of the eye and the inner portion defines a chamber over a cornea of the eye. The micro-device includes an illumination system including a micro-optical element coupled to the body. The micro-optical element is configured to direct photoactivating light to the cornea of the eye when the body is positioned against the surface of the eye. The photoactivating light generates cross-linking activity with a cross-linking agent applied to the cornea.

公开(公告)号：US20240009031A1

公开(公告)日：2024-01-11

申请号：US18471950

申请日：2023-09-21

Applicant: Avedro, Inc.

Inventor： Desmond Christopher Adler ,  Reza Zadno ,  Paul Bavier ,  David C. Iannetta ,  Jun Zhang

IPC: A61N5/06 ,  A61F9/00

CPC classification number: A61N5/062 ,  A61F9/0017 ,  A61N2005/0626 ,  A61N2005/0652 ,  A61N2005/0648

Abstract: A micro-device for corneal cross-linking treatment includes a body including an outer portion and an inner portion. The inner portion is coupled to the outer portion which is disposed about a periphery of the inner portion. When the body is against an eye surface, the outer portion contacts the eye surface and the inner portion defines a chamber over a cornea of the eye. The micro-device includes an illumination system including a micro-optical element and an optical fiber. The micro-optical element includes micro-LEDs configured to direct photoactivating light through the inner portion to the cornea of the eye when the body is positioned against the surface of the eye. The photoactivating light generates cross-linking activity with a cross-linking agent applied to the cornea. The optical fiber couples the micro-optical element to a light source and includes a surface configured to reflect the photoactivating light to the micro-optical element.