公开(公告)号：US20240026344A1

公开(公告)日：2024-01-25

申请号：US18031808

申请日：2021-10-13

Applicant: Avitide LLC

Inventor： Brandon Kier ,  Molly North ,  Sarmistha Bhattacharya ,  Thomas Scanlon ,  Warren Kett

IPC: C12N15/10

CPC classification number: C12N15/1037

Abstract: The present disclosure relates to the field of affinity chromatography, and more specifically to the provision of nucleic acid and polypeptide libraries encoding three-helix bundle protein domains suitable for selecting affinity ligands that specifically binds to a target molecule of interest. The disclosure also relates to methods of using those libraries to identify and isolate such affinity ligands to a target molecule.