公开(公告)号：US09331113B2

公开(公告)日：2016-05-03

申请号：US13695267

申请日：2011-04-25

申请人： Aydogan Ozcan ,  Ahmet F. Coskun ,  Ikbal Sencan ,  Ting-Wei Su

发明人： Aydogan Ozcan ,  Ahmet F. Coskun ,  Ikbal Sencan ,  Ting-Wei Su

IPC分类号： G01J1/04 ,  H01J3/14 ,  H01L27/00 ,  H01L27/146 ,  G01N21/64

CPC分类号： H01L27/14625 ,  G01N21/64 ,  G01N21/6456 ,  G01N21/648 ,  G01N2021/6471 ,  G01N2021/6482 ,  G01N2021/6484 ,  G01N2201/0833

摘要： An imaging device uses a fiber optic faceplate (FOF) with a compressive sampling algorithm for the fluorescent imaging of a sample over an large field-of-view without the need for any lenses or mechanical scanning. The imaging device includes a sample holder configured to hold a sample and a prism or hemispherical glass surface disposed adjacent the sample holder on a side opposite the lower surface of the sample holder. A light source is configured to illuminate the sample via the prism or the hemispherical surface, wherein substantially all of the light is subject to total internal reflection at the lower surface of the sample holder. The FOF is disposed adjacent to the lower surface of the sample holder, the fiber optic array having an input side and an output side. The device includes an imaging sensor array disposed adjacent to the output side of the fiber optic array.

摘要翻译： 成像装置使用具有压缩采样算法的光纤面板（FOF），用于在大视野范围内的样品的荧光成像，而不需要任何透镜或机械扫描。 成像装置包括：样本保持器，其被配置为保持样本和邻近样本保持器设置在与样本保持器的下表面相对的一侧的棱镜或半球形玻璃表面。 光源被配置为经由棱镜或半球形表面照射样品，其中基本上所有的光在样品保持器的下表面处受到全内反射。 FOF设置在样品架的下表面附近，光纤阵列具有输入侧和输出侧。 该装置包括邻近光纤阵列的输出侧设置的成像传感器阵列。

公开(公告)号：US20130092821A1

公开(公告)日：2013-04-18

申请号：US13695267

申请日：2011-04-25

申请人： Aydogan Ozcan ,  Ahmet F. Coskun ,  Ikbal Sencan ,  Ting-Wei Su

发明人： Aydogan Ozcan ,  Ahmet F. Coskun ,  Ikbal Sencan ,  Ting-Wei Su

IPC分类号： H01L27/146 ,  G01N21/64

CPC分类号： H01L27/14625 ,  G01N21/64 ,  G01N21/6456 ,  G01N21/648 ,  G01N2021/6471 ,  G01N2021/6482 ,  G01N2021/6484 ,  G01N2201/0833

摘要： An imaging device uses a fiber optic faceplate (FOF) with a compressive sampling algorithm for the fluorescent imaging of a sample over an large field-of-view without the need for any lenses or mechanical scanning. The imaging device includes a sample holder configured to hold a sample and a prism or hemispherical glass surface disposed adjacent the sample holder on a side opposite the lower surface of the sample holder. A light source is configured to illuminate the sample via the prism or the hemispherical surface, wherein substantially all of the light is subject to total internal reflection at the lower surface of the sample holder. The FOF is disposed adjacent to the lower surface of the sample holder, the fiber optic array having an input side and an output side. The device includes an imaging sensor array disposed adjacent to the output side of the fiber optic array.

摘要翻译： 成像装置使用具有压缩采样算法的光纤面板（FOF），用于在大视野范围内的样品的荧光成像，而不需要任何透镜或机械扫描。 成像装置包括：样本保持器，其被配置为保持样本和邻近样本保持器设置在与样本保持器的下表面相对的一侧的棱镜或半球形玻璃表面。 光源被配置为经由棱镜或半球形表面照射样品，其中基本上所有的光在样品保持器的下表面处受到全内反射。 FOF设置在样品架的下表面附近，光纤阵列具有输入侧和输出侧。 该装置包括邻近光纤阵列的输出侧设置的成像传感器阵列。