公开(公告)号：US08057823B2

公开(公告)日：2011-11-15

申请号：US10220506

申请日：2001-03-02

申请人： Béatrice Heurtault ,  Patrick Saulnier ,  Jean-Pierre Benoit ,  Jacques-Emile Proust ,  Brigitte Pech ,  Joël Richard

发明人： Béatrice Heurtault ,  Patrick Saulnier ,  Jean-Pierre Benoit ,  Jacques-Emile Proust ,  Brigitte Pech ,  Joël Richard

IPC分类号： A61K9/16 ,  A61K9/14

CPC分类号： A61K9/5123 ,  A61K9/5146 ,  B01F17/0028 ,  B01F17/0064 ,  B01F17/0085 ,  B01J13/0026 ,  B01J13/06

摘要： The invention concerns nanocapsules, in particular with an average size less than 50 nm, consisting of an essentially lipid core liquid or semiliquid at room temperature, coated with an essentially lipid film solid at room temperature having a thickness of 2-10 nm. The invention also concerns a method for preparing same which consists in producing a reverse phase of an aqueous emulsion brought about by several temperature raising and lowering cycles. Said lipid nanocapsules are particularly designed for producing a medicine.

摘要翻译： 本发明涉及纳米胶囊，特别是平均尺寸小于50nm，由在室温下基本上是脂质核心液体或半液体组成，在室温下涂覆有基本上脂质膜固体，其厚度为2-10nm。 本发明还涉及一种制备方法，其包括通过几个升温和降温循环产生水乳液的反相。 所述脂质纳米胶囊特别设计用于生产药物。

公开(公告)号：US20090238865A1

公开(公告)日：2009-09-24

申请号：US12474958

申请日：2009-05-29

申请人： Beatrice Heurtault ,  Patrick Saulnier ,  Jean-Pierre Benoit ,  Jacques-Emile Proust ,  Brigitte Pech ,  Joel Richard

发明人： Beatrice Heurtault ,  Patrick Saulnier ,  Jean-Pierre Benoit ,  Jacques-Emile Proust ,  Brigitte Pech ,  Joel Richard

IPC分类号： A61K9/127 ,  A61K47/12

CPC分类号： A61K9/5123 ,  A61K9/5146 ,  B01F17/0028 ,  B01F17/0064 ,  B01F17/0085 ,  B01J13/0026 ,  B01J13/06

摘要： The invention concerns nanocapsules, in particular with an average size less than 50 nm, consisting of an essentially lipid core liquid or semiliquid at room temperature, coated with an essentially lipid film solid at room temperature having a thickness of 2-10 nm. The invention also concerns a method for preparing same which consists in producing a reverse phase of an aqueous emulsion brought about by several temperature raising and lowering cycles. Said lipid nanocapsules are particularly designed for producing a medicine.

摘要翻译： 本发明涉及纳米胶囊，特别是平均尺寸小于50nm，由在室温下基本上是脂质核心液体或半液体组成，在室温下涂覆有基本上脂质膜固体，其厚度为2-10nm。 本发明还涉及一种制备方法，其包括通过几个升温和降温循环产生水乳液的反相。 所述脂质纳米胶囊特别设计用于生产药物。