公开(公告)号：US20020087024A1

公开(公告)日：2002-07-04

申请号：US09970937

申请日：2001-10-05

Applicant: BASF Aktiengesellschaft

Inventor： Thomas Greindl ,  Gerold Braun ,  Friedrich Wirsing ,  Georg Krug

IPC: C07C253/08

CPC classification number: C07C253/00 ,  Y02P20/582 ,  C07C255/04 ,  C07C255/05

Abstract: The invention relates to a continuous process, carried out in two steps, for the cyanoalkylation of compounds having one or more NH functions by reaction thereof with carbonyl compounds and hydrocyanic acid, in which the first step is carried out without pressure at a temperature which is below the boiling point of the reaction mixture.

Abstract translation: 本发明涉及通过与羰基化合物和氢氰酸反应使其具有一个或多个NH官能团的化合物的氰基烷基化进行两步的连续方法，其中第一步在没有压力的情况下在温度为 低于反应混合物的沸点。

公开(公告)号：US20010034457A1

公开(公告)日：2001-10-25

申请号：US09875995

申请日：2001-06-08

Applicant: BASF AKTIENGESELLSCHAFT

Inventor： Rainer Rahm ,  Thomas Greindl ,  Alfred Oftring ,  Guenter Oetter ,  Juergen Detering ,  Gerold Braun

IPC: C07C253/08

CPC classification number: C07C229/08 ,  C07C229/16 ,  C07C253/00 ,  C07C255/25

Abstract: A process for preparing compounds of the formula IIb 1 nullwhere R is C6-C30-alkyl or C6-C30-alkenyl, which may additionally have upto 5 hydroxyl groups, formyl groups, C1-C4-alkoxy groups, phenoxy groups or C1-C4-alkoxycarbonyl groups as substituents and may be interrupted by upto 5 nonadjacent oxygen atoms, or alkoxylate groups of the formula null(CH2)knullOnull(A1O)mnull(A2O)nnullY where A1 and A2 are, independently of one another, 1,2-alkylene groups having 2 to 4 carbon atoms, Y is hydrogen, C1-C12-alkyl, phenyl or C1-C4-alkoxycarbonyl, and k is 1, 2 or 3, and m and n are each numbers from 0 to 50, and the total of mnulln must be at least 4, by reacting iminodiacetonitrile with aldehydes of the formula RnullCHO and HCN or alkali metal cyanides, the process being carried out a) in the absence of an organic solvent and in the presence of a Lewis or Brnullnsted acid, or b) in the presence or absence of an organic solvent and in the presence of an emulsifier, or c) in the presence or absence of an organic solvent and under a pressure in the range from 1 to 40 bar.

Abstract translation: 制备式IIb化合物的方法，其中R是C 6 -C 30 - 烷基或C 6 -C 30烯基，其可另外具有多达5个羟基，甲酰基，C 1 -C 4 - 烷氧基，苯氧基或C 1 -C 4 - 烷氧基羰基作为取代基，并且可以被至多5个不相邻的氧原子间隔或式 - （CH2）kO-（A1O）m-（A2O）nY的烷氧基化物，其中A1和A2彼此独立地为1,2 具有2至4个碳原子的亚烷基，Y是氢，C 1 -C 12 - 烷基，苯基或C 1 -C 4 - 烷氧基羰基，k是1,2或3，m和n各自为0至50， 通过使亚氨基二乙腈与式R-CHO和HCN或碱金属氰化物的醛反应，m + n的总和必须至少为4，该方法在不存在有机溶剂的情况下进行，并且在 路易斯或布朗斯台德酸，或b）在有机溶剂存在或不存在下，在乳化剂存在下，或c）在有机溶剂存在或不存在下， 并在1至40巴的压力范围内。