公开(公告)号：US20180334660A1

公开(公告)日：2018-11-22

申请号：US16052853

申请日：2018-08-02

Applicant: BASF Enzymes LLC

Inventor： Walter CALLEN ,  Toby RICHARDSON ,  Gerhard FREY ,  Jay M. SHORT ,  Eric J. MATHUR ,  Kevin A. Gray ,  Janne S. KEROVUO ,  Malgorzata SLUPSKA

IPC: C12N9/28 ,  C12N9/26 ,  C12P19/14 ,  A21D8/04 ,  C12P19/04

CPC classification number: C12N9/2417 ,  A21D8/042 ,  C12N9/2414 ,  C12P19/04 ,  C12P19/14 ,  C12Y302/01001 ,  Y02E50/16 ,  Y02E50/17

Abstract: The invention relates to alpha amylases and to polynucleotides encoding the alpha amylases. In addition, methods of designing new alpha amylases and methods of use thereof are also provided. The alpha amylases have increased activity and stability at acidic, neutral and alkaline pH and increased temperature.

公开(公告)号：US20160068832A1

公开(公告)日：2016-03-10

申请号：US14832603

申请日：2015-08-21

Applicant: BASF Enzymes LLC

Inventor： David P. WEINER ,  Alexander VARVAK ,  Toby RICHARDSON ,  Mircea PODAR ,  Ellen BURKE ,  Shaun HEALEY

IPC: C12N9/88 ,  C12P13/24 ,  D06M16/00 ,  C12P13/22

CPC classification number: C12N9/88 ,  C12P7/42 ,  C12P13/222 ,  C12P13/225 ,  C12P13/24 ,  C12Y403/01005 ,  C12Y403/01023 ,  D06M16/003

Abstract: This invention provides polypeptides having lyase activity, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. In one aspect, the invention is directed to polypeptides having ammonia lyase activity, e.g., phenylalanine ammonia lyase, tyrosine ammonia lyase and/or histidine ammonia lyase activity, including thermostable and thermotolerant activity, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. The polypeptides of the invention can be used in a variety of pharmaceutical, agricultural and industrial contexts.

Abstract translation: 本发明提供了具有裂解酶活性的多肽，编码这些多肽的多核苷酸，以及制备和使用这些多核苷酸和多肽的方法。 一方面，本发明涉及具有氨裂解酶活性的多肽，例如苯丙氨酸氨裂解酶，酪氨酸氨裂解酶和/或组氨酸氨裂解酶活性，包括耐热和耐热活性，以及​​编码这些酶的多核苷酸，以及制备和使用这些多核苷酸 和多肽。 本发明的多肽可用于多种药物，农业和工业环境。

公开(公告)号：US20200085070A1

公开(公告)日：2020-03-19

申请号：US16277335

申请日：2019-02-15

Applicant: BASF Enzymes LLC

Inventor： Walter CALLEN ,  Toby RICHARDSON ,  Gerhard FREY ,  Kevin A. GRAY ,  Janne S. KEROVUO ,  Malgorzata SLUPSKA ,  Nelson R. BARTON ,  Eileen O'DONOGHUE ,  Carl MILLER

IPC: A21D8/04 ,  C12N9/26 ,  C12P19/20 ,  C12P19/16 ,  C12P19/14 ,  C12C5/00 ,  C12N9/34

Abstract: In one aspect, the invention is directed to polypeptides having an amylase activity, polynucleotides encoding the polypeptides, and methods for making and using these polynucleotides and polypeptides. In one aspect, the polypeptides of the invention can be used as amylases, for example, alpha amylases, to catalyze the hydrolysis of starch into sugars. In one aspect, the invention provides delayed release compositions comprising a desired ingredient coated by a latex polymer coating.