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公开(公告)号:US11634698B2
公开(公告)日:2023-04-25
申请号:US16954276
申请日:2018-12-10
申请人: BASF SE
发明人: Xuqiu Tan , Kenneth Barrett , Jared Dennis , Dongmei Ren , Corey Dodge , Bin Zhang
IPC分类号: C12N9/22 , A23K20/147 , A23K20/189 , A23L29/00 , A23L33/18 , C11D3/386
摘要: Disclosed herein are polypeptides having nuclease activity. Some of the polypeptides having nuclease activity were generated by an improved gene site mutagenesis (“GSSM”) method or the tailored multi-site combinatorial assembly (“TMCA”) method. Also disclosed are compositions and kits comprising the polypeptides having nuclease activity, and methods for making and using these polypeptides, compositions and kits.