公开(公告)号：US20190274939A1

公开(公告)日：2019-09-12

申请号：US16302466

申请日：2017-05-19

Applicant: BASF SE

Inventor： Heike FLOESSER-MUELLER ,  Stephanie ACKER ,  Louis DANOUX ,  Henning URCH ,  Julie GRUMELARD ,  Thomas EHLIS ,  Bernd HERZOG ,  Ullrich MENGE ,  Antony YOUNG ,  Karl LAWRENCE

IPC: A61K8/49 ,  A61Q17/04 ,  A61K8/81 ,  A61K8/06 ,  A61K8/58

Abstract: Disclosed are aqueous dispersions (A), comprising a micronized organic UV filter (a) selected from (a1) the micronized compound of formula (1), wherein R1 and R2 independently from each other are C1-C20alkyl; C2-C20alkenyl; C3-C10ocycloalkyl; C3-C10cycloalkenyl; or R1 and R2 together with the linking nitrogen atom form a 5- or 6-membered heterocyclic ring; A is —N(R3)—; —O—; or the direct bond; B is a bivalent radical selected from alkylene, cycloalkylene alkenylene or phenylene radical which is optionally substituted by a carbonyl- or carboxy group; a radical of formula *—CH2—C≡═C—CH2—; or the divalent radical *-B-* corresponds to the formula (1a), wherein n1 is a number from 1 to 3; A is —N(R3)—; or —O—; and R3 is hydrogen; C1-C5alkyl; or hydroxy-C1-C5alkyl; (a2) the micronized compound of formula (2), wherein T1 is hydrogen; C1-C12alkyl; preferably iso-octyl, or C1-C4alkyl substituted by phenyl; (a3) the micronized compound of formula (3a); wherein R4 and R5 independently from each other are hydrogen; C1-C18alkyl; or C6-C12acryl; R6, R7 and R8 independently from each other, are hydrogen; C1-C18alkyl; or a radical of formula (3b); wherein R9, R10 and R11 independently from each other, are hydrogen; or C1-C18alkyl; (a4) the micronized compound of formula (4); wherein R12 and R13, independently from each other, represent hydrogen; halogen; C1-C12alkyl: C1-C18hydroxy; C1-C18alkoxy; poly(ethoxy)-alkoxy with a C1-C4 alkyl fragment and an ethoxy number ranging from 1 to 4; C1-C4mono- or dialkyl amino, R14 represents halogen; hydroxy; amino; phenyl which is optionally substituted 1 to 3 times by a hydroxy radical situated at least in a para or phenyl position, possibly 1 to 3 times substituted in an ortho, meta or para position by a C1-C12alkoxy or cyano or C1-C7alkyl-amino group; and (b) a vinylpyrrolidone copolymer or homopolymer.

公开(公告)号：US20160067158A1

公开(公告)日：2016-03-10

申请号：US14890307

申请日：2014-05-06

Applicant: BASF SE

Inventor： Matthias HLOUCHA ,  Esther KUESTERS ,  Stephanie ACKER ,  Heike FLOESSER-MUELLER ,  Jasmin SCHORB

IPC: A61K8/33 ,  A61K8/41 ,  A61K8/49 ,  A61Q17/04 ,  A61K8/37

CPC classification number: A61K8/33 ,  A61K8/37 ,  A61K8/39 ,  A61K8/415 ,  A61K8/4966 ,  A61K2800/596 ,  A61Q17/04

Abstract: The invention relates to highly concentrated agents for the preparation of sunscreen final formulations, comprising (a) 15 to 50 wt. % of oily substance, (b) 4 to 30 wt. % of anionic surfactant, (c) 0.5 to 25 wt. % of further co-surfactant which differs from (b), (d) 25 to 75 wt. % of UV filter, and (e) optionally water and/or auxiliary substances to 100 wt. %. and its use for the preparation of sunscreen final formulations and the preparation thereof.

Abstract translation: 本发明涉及用于制备防晒剂最终制剂的高度浓缩剂，其包含（a）15至50wt。 ％的油性物质，（b）4〜30wt。 ％的阴离子表面活性剂，（c）0.5〜25wt。 （b），（d），25〜75wt。％的不同的进一步助表面活性剂的％ ％的UV过滤器，和（e）任选的水和/或辅助物质至100wt。 ％。 以及其用于制备防晒霜最终配方及其制备的用途。