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    UV FILTER COMPOSITIONS AND METHODS OF PREPARATION AND USE THEREOF
    4.
    发明申请
    UV FILTER COMPOSITIONS AND METHODS OF PREPARATION AND USE THEREOF 有权

    公开(公告)号：US20210231644A1

    公开(公告)日：2021-07-29

    申请号：US17051040

    申请日：2019-04-26

    Applicant: BASF SE

    Inventor： Stephanie ACKER ,  Sascha PAWLOWSKI ,  Bernd HERZOG

    IPC: G01N33/50 ,  A61K8/18 ,  A61Q17/04

    Abstract: Disclosed herein are ultraviolet (UV) filter compositions and methods relating to their preparation and use. The compositions and related method of preparation may include combining at least one or at least two UV filters with at least one other ingredient, wherein each of the UV filters is selected to have an overall environmental hazard score of 1.5 to 7.0, and determining an ecotoxicological value of the composition, wherein the ecotoxicological value ranges from 0 to 350.

    MICRO-PARTICULATE ORGANIC UV ABSORBER COMPOSITION
    6.
    发明申请
    MICRO-PARTICULATE ORGANIC UV ABSORBER COMPOSITION 审中-公开

    公开(公告)号：US20190274939A1

    公开(公告)日：2019-09-12

    申请号：US16302466

    申请日：2017-05-19

    Applicant: BASF SE

    Inventor： Heike FLOESSER-MUELLER ,  Stephanie ACKER ,  Louis DANOUX ,  Henning URCH ,  Julie GRUMELARD ,  Thomas EHLIS ,  Bernd HERZOG ,  Ullrich MENGE ,  Antony YOUNG ,  Karl LAWRENCE

    IPC: A61K8/49 ,  A61Q17/04 ,  A61K8/81 ,  A61K8/06 ,  A61K8/58

    Abstract: Disclosed are aqueous dispersions (A), comprising a micronized organic UV filter (a) selected from (a1) the micronized compound of formula (1), wherein R1 and R2 independently from each other are C1-C20alkyl; C2-C20alkenyl; C3-C10ocycloalkyl; C3-C10cycloalkenyl; or R1 and R2 together with the linking nitrogen atom form a 5- or 6-membered heterocyclic ring; A is —N(R3)—; —O—; or the direct bond; B is a bivalent radical selected from alkylene, cycloalkylene alkenylene or phenylene radical which is optionally substituted by a carbonyl- or carboxy group; a radical of formula *—CH2—C≡═C—CH2—; or the divalent radical *-B-* corresponds to the formula (1a), wherein n1 is a number from 1 to 3; A is —N(R3)—; or —O—; and R3 is hydrogen; C1-C5alkyl; or hydroxy-C1-C5alkyl; (a2) the micronized compound of formula (2), wherein T1 is hydrogen; C1-C12alkyl; preferably iso-octyl, or C1-C4alkyl substituted by phenyl; (a3) the micronized compound of formula (3a); wherein R4 and R5 independently from each other are hydrogen; C1-C18alkyl; or C6-C12acryl; R6, R7 and R8 independently from each other, are hydrogen; C1-C18alkyl; or a radical of formula (3b); wherein R9, R10 and R11 independently from each other, are hydrogen; or C1-C18alkyl; (a4) the micronized compound of formula (4); wherein R12 and R13, independently from each other, represent hydrogen; halogen; C1-C12alkyl: C1-C18hydroxy; C1-C18alkoxy; poly(ethoxy)-alkoxy with a C1-C4 alkyl fragment and an ethoxy number ranging from 1 to 4; C1-C4mono- or dialkyl amino, R14 represents halogen; hydroxy; amino; phenyl which is optionally substituted 1 to 3 times by a hydroxy radical situated at least in a para or phenyl position, possibly 1 to 3 times substituted in an ortho, meta or para position by a C1-C12alkoxy or cyano or C1-C7alkyl-amino group; and (b) a vinylpyrrolidone copolymer or homopolymer.

    SUNSCREEN FORMULATIONS OPTIMIZED FOR THE FORMATION OF VITAMIN D
    7.
    发明申请
    SUNSCREEN FORMULATIONS OPTIMIZED FOR THE FORMATION OF VITAMIN D 审中-公开

    公开(公告)号：US20180200170A1

    公开(公告)日：2018-07-19

    申请号：US15327071

    申请日：2015-07-24

    Applicant: BASF SE

    Inventor： Bernd HERZOG ,  Dieter KOCKOTT ,  Heike FLÖSSER-MÜLLER

    IPC: A61K8/44 ,  A61Q17/04 ,  A61K8/49 ,  A61K8/35 ,  A61K8/29 ,  A61K8/37

    CPC classification number: A61K8/445 ,  A61K8/29 ,  A61K8/35 ,  A61K8/37 ,  A61K8/40 ,  A61K8/415 ,  A61K8/4926 ,  A61K8/4946 ,  A61K8/496 ,  A61K8/4966 ,  A61Q17/04

    Abstract: The present invention relates to a sunscreen formulation comprising at least one of the UV filters (A) selected from (a) triazine derivatives; (b) cinnamic acid derivatives; (c) bis-resorcinyl triazines; (f) benzimidazole derivatives; (is) 4-Methylbenzylidene Camphor; (h) benzoyl piperazine derivatives; (j) benzoxazole derivatives; (k) diarylbutadiene derivatives; (I) phenyl benzotriazole derivatives; (n) benzylidene malonates; (o3) TEA-Salicylate; (r) imidazoline derivatives; (u) inorganic UV filters selected from metal oxides; (v) naphthalates; and (w) merocyanine derivatives; and optionally comprising at least one of the UV filters (B) selected from (d) aminobenzophenone derivatives; (e) dibenzoylmethane derivatives; (g) β,β-Diphenylacrylate derivatives; (i5) camphor derivatives different from; (o3) salicylate derivatives different from; (p) anthranilate derivatives; and (s) benzalmalonate derivatives; wherein the ratio R of the effective irradiance for previtamin D3 formation Epvd to the effective irradiance for erythema formation Eer on the skin is at least 1.8, for increasing the transmittance of UV radiation on human skin for the production of cholecalciferol (previtamin D3) and simultaneously for the use in a method for protecting the human skin against UV radiation when exposed to the sun, which method comprises applying said sunscreen formulation to the skin.

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