Abstract:
The invention provides a continuous process for producing polymer-shell nanoparticles, especially in the form of aqueous dispersions, using a high-pressure homogenizer.
Abstract:
The present invention relates to a process for producing hybrid nanoparticles comprising at least one inorganic material and at least one polymeric organic material, comprising at least the steps of (A) providing an emulsion comprising a disperse phase (I) comprising at least one pre-cursor compound of the at least one polymeric organic material and at least one compound which brings about the precipitation of the at least one inorganic material, a continuous aqueous phase (II), and optionally at least one compound which brings about the polymerization of the at least one precursor compound, this being present in the disperse phase (I), in the continuous aqueous phase (II) or in both phases (I) and (II), (B) adding at least one precursor compound of the at least one inorganic material to the emulsion from step (A), so as to form the at least one inorganic material by precipitation in the disperse phase, (C) optionally adding at least one compound which brings about the polymerization of the at least one precursor compound of the at least one polymeric organic material if this has not been done in step (A), and (D) polymerizing the at least one precursor compound of the at least one polymeric organic material. The present invention additionally relates to nanoparticles producible by the process according to the invention, and to the use of inventive nanoparticles in optical, electronic, chemical, agro-chemical, medical, pharmaceutical and/or biotechnological systems or for the administration of at least one active ingredient.
Abstract:
Provided herein is a process for preparing an aqueous dispersion of microparticles containing a water-insoluble, solid, non-polymeric, organic active or functional material (M) and an aminoplast resin (A) which surrounds or embeds material (M). The process includes the following steps: i) providing an aqueous slurry of the material (M) in the form of coarse particles; ii) subjecting the aqueous slurry to shear forces such that the coarse particles of the material (M) are comminuted and an aqueous suspension of fine particles of the material (M) is obtained; and iii) performing a polycondensation of an aminoplast pre-condensate during step (ii) or in the aqueous suspension of the fine particles of the material (M) obtained in step (ii); wherein step (ii) is performed in the presence of at least one protective colloid and in the presence of at least a portion of the aminoplast pre-condensate subjected to the polycondensation of step (iii).
Abstract:
The invention provides a continuous process for producing polymer-shell nanoparticles, especially in the form of aqueous dispersions, using a high-pressure homogenizer.