公开(公告)号：US20230041211A1

公开(公告)日：2023-02-09

申请号：US17786127

申请日：2020-12-15

Applicant: BASF SE

Inventor： Michael BREUER ,  Julia Ena HARTIG ,  Robert THUMMER ,  Heike BRUESER ,  Stephanie RENZ ,  Michael Guenter BRAUN ,  Oliver OSWALD ,  Roland MINGES ,  Jens O. KROEMER ,  Heiko BABEL

IPC: C12N15/01 ,  C12N1/20 ,  C12N15/74 ,  C12N15/70 ,  C12P5/00

Abstract: The invention pertains to novel methods to increase the tolerance of microbial host cells to toxic substance, for example terpenes and alcohols and other membrane disrupting substances, as well as modified organism with such an increased tolerance a compared to the unmodified organism.