公开(公告)号：US20240294894A1

公开(公告)日：2024-09-05

申请号：US18572942

申请日：2022-06-24

Applicant: BASF SE

Inventor： Max Fabian Felle ,  Mathis Appelbaum ,  Christopher Sauer ,  Stefan Janewein

IPC: C12N9/54 ,  C12N15/75

CPC classification number: C12N9/54 ,  C12N15/75 ,  C12Y304/21062 ,  C12N2800/101

Abstract: The present invention relates to a Bacillus host cell for increased production of biological compounds. Specifically, the invention relates to a Bacillus host with genetic modifications in the remA and/or remB gene. The present invention further relates to a method for increased production of at least one polypeptide of interest based on cultivating the bacterial host cell of the present invention.