公开(公告)号：US3895020A

公开(公告)日：1975-07-15

申请号：US20615871

申请日：1971-12-08

Applicant: BAYER AG

Inventor： SCHOLL HANS-JOACHIM ,  KLAUKE ERICH ,  GREWE FERDINAND ,  HAMMANN INGEBORG

IPC: A01N47/02 ,  A01N47/08 ,  C07D277/20 ,  C07D277/42 ,  C07D277/48 ,  C07D513/04 ,  C07D99/10

CPC classification number: C07D277/20 ,  C07D277/42 ,  C07D277/48

Abstract: 4,5-Bis-(trifluoromethylimino)-thiazolidines are prepared by reacting the thiol form of a thiourea or a thiocarboxylic acid amide having at least one hydrogen atom on each urea of amide nitrogen atom with perfluoro-2,5-diazahexa-2,4-diene in the presence of a hydrogen fluoride acceptor at a temperature of about -50* to 120*C, in accordance with the following formula

in which Z is N-R or

and R, R'', R'''' and R'''''' each is hydrogen or various optionally substituted hydrocarbon or heterocyclic radicals, several of them together possibly forming a heterocyclic ring. The invention also extends to compositions containing, and methods of using, the new compounds to combat fungi, insects and acarids.

Abstract translation: 通过使酰胺氮原子的每个尿素上具有至少一个氢原子的硫脲或硫代羧酸酰胺的硫醇形式与全氟-2,5-二氮杂六-2反应制备4,5-双 - （三氟甲基亚氨基） 在氟化氢受体存在下，在约-50℃至120℃的温度下，根据下式计算：SH FC = N-CF 3 SC = N-CF 3 Z = C ANGLE + | - > Z = C ANGLE | NH F-C = N-CF 3 NC = N-CF 3 | | R“'R”，其中Z为= NR或} R'} = C ANGLE} R“'，R，R '，R“和R”'各自为氢或各种任选取代的烃或杂环基，其中几个可能形成杂环。

公开(公告)号：US3787435A

公开(公告)日：1974-01-22

申请号：US3787435D

申请日：1971-12-08

Applicant: BAYER AG

Inventor： SCHOLL HANS-JOACHIM ,  KLAUKE ERICH ,  GREWE FERDINAND ,  HAMMANN INGEBORG

IPC: A01N43/50 ,  A01N43/76 ,  A01N43/90 ,  C07D233/96 ,  C07D263/48 ,  C07D487/04 ,  C07D487/06 ,  C07D498/04 ,  C07D49/34 ,  C07D57/02

CPC classification number: C07D487/04 ,  C07D233/96 ,  C07D263/48

Abstract: AND R, R'', R" AND R''" EACH IS HYDROGEN OR VARIOUS OPTIONALL FIG-03 AND R, R'', R" AND R''" EACH IS HYDROGEN OR VARIOUS OPTIONALLY SUBSTITUTED HYDROCARBON OR HETEROCYCLIC RADICALS, SEVERAL OF THEM TOGETHER POSSIBLY FORMING A HETEROCYCLIC RING. THE INVENTION ALSO EXTENDS TO COMPOSITIONS CONTAINING, AND METHODS OF USING, THE NEW COMPOUNDS TO COMBAT FUNGI, INSECTS AND ACARIDS.

=C(-R'')-R"

IN WHICH Z IS OXYGEN, R-N= OR

Z=C
Z=C(-X-H)-NH(-R"'') + F3C-N=CF-CF=N-CF3 --->

4.5-BIS-(TRIFLUOROMETHYLIMINO)OXAZOLES OR DIAZOLES ARE PREPARED BY REACTING THE ENOL FORM OF AN AMIDE OR AN IMIDE OF A CARBOXYLIC ACID OR CARBONIC ACID, HAVING AT LEAST ONE HYDROGEN ATOM ON EACH OF AN OXYGEN AND NITROGEN OR TWO NITROGEN ATOMS VICINAL TO THE AMIDE CARBON ATOM, WITH PERFLUORO-2,4-DIAZAHEXA-2,4-DIENE IN THE PRESENCE OF A HYDROGEN FLUORIDE ACCEPTOR AT A TEMPERATURE OF ABOUT -50 TO 120*C., IN ACCORDANCE WITH THE FOLLOWING FORMULA

公开(公告)号：US3899584A

公开(公告)日：1975-08-12

申请号：US41770373

申请日：1973-11-20

Applicant: BAYER AG

Inventor： SCHOLL HANS-JOACHIM ,  KLAUKE ERICH ,  GREWE FERDINAND ,  HAMMANN INGEBORG

IPC: C07D277/20 ,  C07D277/42 ,  A01N9/12 ,  A01N9/22

CPC classification number: C07D277/20

Abstract: Fungicidal, insecticidal and acaricidal compositions containing, and methods of combating fungi, insects and acarids using, novel 4,5-bis-(trifluoromethylimino)-thiazolidines of the formula

IN WHICH Z is R-N or

AND R, R'', R'''' and R'''''' each is hydrogen; alkyl, alkenyl or alkynyl with up to 8 carbon atoms optionally substituted by halogen, cyano, lower alkoxy or alkylmercapto; optionally lower-alkylsubstituted cycloalkyl; carbalkoxy; aralkyl with up to 2 carbon atoms in the alkyl moiety; aryl with up to 14 carbon atoms in the ring system, the aryl radicals optionally being substituted by halogen, cyano, nitro, lower alkyl, haloalkyl, lower alkoxy or alkylmercapto; a 5- to 7-membered heterocyclic ring or a radical which together with Z and the N-atom of the thiazolidine ring forms a further 5- to 7-membered ring, the heterocyclic rings optionally being substituted with halogen, cyano, nitro or lower alkyl, or being fused with a benzene ring which is optionally partially hydrogenated.

Abstract translation: 含有本发明的杀真菌剂，杀虫剂和杀螨剂的组合物，以及使用式IN的化合物，其中Z =或AND R，R'，R“'的新的4,5-双（三氟甲基亚氨基）噻唑烷与防治真菌，昆虫和螨的方法 和R“'各自为氢; 具有至多8个碳原子的烷基，烯基或炔基，任选被卤素，氰基，低级烷氧基或烷基巯基取代; 任选的低级烷基取代的环烷基; 碳烷氧基 在烷基部分具有至多2个碳原子的芳烷基; 在环系中具有至多14个碳原子的芳基，芳基任选被卤素，氰基，硝基，低级烷基，卤代烷基，低级烷氧基或烷基巯基取代; 5至7元杂环或与Z和噻唑烷环的N-原子一起形成另外的5-至7-元环的基团，任选被卤素，氰基，硝基或低级取代的杂环 或与任选部分氢化的苯环稠合。

公开(公告)号：US3694507A

公开(公告)日：1972-09-26

申请号：US3694507D

申请日：1971-03-11

Applicant: BAYER AG

Inventor： SCHOLL HANS-JOACHIM ,  KLAUKE ERICH

IPC: A01N47/08 ,  C07C119/00

CPC classification number: A01N47/08

Abstract: Perfluoro-2,5-diazahexa-2,4-diene (CF3-N CF-CF N-CF3) is prepared by reacting N,N''-bis(trifluoromethyl) tetrafluoroethylene diamine (CF3-NH-CF2-CF2-NH-CF3) with sodium fluoride at about 20* to about 70* C.

Abstract translation: 通过使N，N'-双（三氟甲基）四氟乙烯二胺（CF 3 -NH-CF 2 -CF 2 - ）（CH 3） NH-CF 3）与氟化钠在约20℃至约70℃