公开(公告)号：US3895020A

公开(公告)日：1975-07-15

申请号：US20615871

申请日：1971-12-08

Applicant: BAYER AG

Inventor： SCHOLL HANS-JOACHIM ,  KLAUKE ERICH ,  GREWE FERDINAND ,  HAMMANN INGEBORG

IPC: A01N47/02 ,  A01N47/08 ,  C07D277/20 ,  C07D277/42 ,  C07D277/48 ,  C07D513/04 ,  C07D99/10

CPC classification number: C07D277/20 ,  C07D277/42 ,  C07D277/48

Abstract: 4,5-Bis-(trifluoromethylimino)-thiazolidines are prepared by reacting the thiol form of a thiourea or a thiocarboxylic acid amide having at least one hydrogen atom on each urea of amide nitrogen atom with perfluoro-2,5-diazahexa-2,4-diene in the presence of a hydrogen fluoride acceptor at a temperature of about -50* to 120*C, in accordance with the following formula

in which Z is N-R or

and R, R'', R'''' and R'''''' each is hydrogen or various optionally substituted hydrocarbon or heterocyclic radicals, several of them together possibly forming a heterocyclic ring. The invention also extends to compositions containing, and methods of using, the new compounds to combat fungi, insects and acarids.

Abstract translation: 通过使酰胺氮原子的每个尿素上具有至少一个氢原子的硫脲或硫代羧酸酰胺的硫醇形式与全氟-2,5-二氮杂六-2反应制备4,5-双 - （三氟甲基亚氨基） 在氟化氢受体存在下，在约-50℃至120℃的温度下，根据下式计算：SH FC = N-CF 3 SC = N-CF 3 Z = C ANGLE + | - > Z = C ANGLE | NH F-C = N-CF 3 NC = N-CF 3 | | R“'R”，其中Z为= NR或} R'} = C ANGLE} R“'，R，R '，R“和R”'各自为氢或各种任选取代的烃或杂环基，其中几个可能形成杂环。

公开(公告)号：US3890386A

公开(公告)日：1975-06-17

申请号：US39283273

申请日：1973-08-29

Applicant: BAYER AG

Inventor： KUHLE ENGELBERT ,  KLAUKE ERICH ,  HAMBURGER BRIGITTE ,  SCHEINPFLUG HANS

IPC: A01N47/24 ,  C07C67/00 ,  C07C313/00 ,  C07C313/32 ,  C07C131/00

CPC classification number: A01N47/24

Abstract: N-(trihalomethylthio)-carbamic acid oxime ester of the formula

IN WHICH R is alkyl; cycloalkyl; or aryl optionally carrying at least one halogen, nitro, C1-C6 alkyl, trifluoromethyl or C1-C6 alkoxy radical; R'' and R'''' each independently is alkyl or alkenyl optionally substituted by an alkoxycarbonyl or amidocarbonyl radical; cycloalkyl; aryl optionally carrying at least one halogen, cyano nitro, trifluoromethyl, C1-C6 alkyl or C1-C6 alkoxy radical; nitrile; halogen; alkoxycarbonyl; or amidocarbonyl; or R'' and R'''', conjointly with the carbon atom that links them, form a cycloalkylidene group with 5 or 6 carbon atoms optionally carrying at least one C1-C6 alkyl, C1-C6 alkylene or cycloalkyl radical; and n is 0, 1, 2 or 3, WHICH POSSESS FUNGICIDAL AND MICROBICIDAL PROPERTIES.

Abstract translation: 式III的N-（三卤代甲硫基） - 氨基甲酸肟酯，其中R是烷基; 环烷基 或任选携带至少一个卤素，硝基，C 1 -C 6烷基，三氟甲基或C 1 -C 6烷氧基的芳基; R'和R“各自独立地是任选被烷氧基羰基或酰氨基羰基取代的烷基或烯基; 环烷基 任选携带至少一个卤素，氰基硝基，三氟甲基，C 1 -C 6烷基或C 1 -C 6烷氧基的芳基; 腈 卤素; 烷氧基羰基 或氨基羰基; 或R'和R“与连接它们的碳原子结合形成具有5或6个碳原子的亚环烷基，任选地带有至少一个C 1 -C 6烷基，C 1 -C 6亚烷基或环烷基; 并且n为0,1,2或3，具有正确的杀真菌和微生物特性。

公开(公告)号：US3592836A

公开(公告)日：1971-07-13

申请号：US3592836D

申请日：1967-12-21

Applicant: BAYER AG

Inventor： UGI IVAR ,  KLAUKE ERICH ,  SCHNABEL EUGEN ,  HOFFMANN PETER

IPC: C07D307/42 ,  C07K1/06 ,  C07C69/00

CPC classification number: C07D307/42 ,  C07K1/063 ,  C07K1/064 ,  C07K1/068

Abstract: ARYLOXYCARBONYL FLUORIDES SUCH AS FURFURYLOXYCARBONYL-, P-METHOXYBENZYLOXYCARBONYL- AND TRIMETHOXYBENZYLOXYCARBONYL-FLUORIDES ARE PROVIDED WHICH ARE USEFUL AS INTERMEDIATES FOR AMINO ACID DERIVATIVES AND ARE OBTAINED FROM CARBONYL-FLUORIDE CHLORIDE BY REACTION WITH THE APPROPRIATE ALCOHOL. THE AMINO ACID DERIVATIVES OF SUCH CARBONYL-FLUORIDES ARE BUILT UP THROUGH ACYLATION OF AMINO ACIDS THEREWITH. THESE AMINO ACID DERIVATIVES ARE USEFUL AS INTERMEDIATES FOR THE SYNTHESIS OF POLYPEPTIDES. THE REACTION OF CARBONYLCHLORIDE-FLUORIDE IS ADVANTAGEOUSLY CARRIED OUT AT TEMPERATURES OF 0 TO 70*C. IN AN INERT SOLVENT AND IN THE PRESENCE OF AN ACID-BINDING AGENT. THE AMINO ACID DERIVATIVES ARE FORMED AT TEMPERATURES BETWEEN +20 AND -20*C. ALSO IN THE PRESENCE OF AN ACID-BINDING AGENT. IMINO ACIDS CAN BE USED IN PLACE OF AMINO ACIDS. THE AMINO- OR IMINO-ACID DERIVATIVES OR ESTERS ARE ADVANTAGEOUSLY PREPARED AT CONSTANT. CONTROLLED PH VALUES, PREFERABLY BY THE USE OF AUTOMATIC PH CONTROL EQUIPMENT.

公开(公告)号：US3558620A

公开(公告)日：1971-01-26

申请号：US3558620D

申请日：1968-05-24

Applicant: BAYER AG

Inventor： BIEN HANS-SAMUEL ,  KLAUKE ERICH ,  WUNDERLICH KLAUS

IPC: C09B62/06 ,  C07D55/46

CPC classification number: C09B62/06

Abstract: ANTHRAQUINONE REACTIVE DYESTUFFS USEFUL IN DYEING HYDROXYL AND NITROGEN-CONTAINING TEXTILES HAVING A NUCLEUS CONSISTING OF A SUBSTITUTED OR UNSUBSTITUTED 1-AMINO-2SULFO-4 (SUBSTITUTED OR UNSUBSTITUTED (4''-AMINO- OR ALKYLENE AMINO-TRIAZINYL) ANALINO) ANTHRAQUINONE. THE DYESTUFFS SHOW IMPROVED FASTNESS PROPERTIES.

公开(公告)号：US3920445A

公开(公告)日：1975-11-18

申请号：US37699173

申请日：1973-07-06

Applicant: BAYER AG

Inventor： WAGNER KLAUS ,  EUE LUDWIG ,  KLAUKE ERICH

IPC: A01N37/48 ,  C07C255/49 ,  A01N9/20

CPC classification number: A01N37/48 ,  C07C255/49

Abstract: Novel 6-nitroaniline compounds of the formula

IN WHICH R1 is hydrogen, substituted or unsubstituted alkyl or aryl, or cycloalkyl; R2 is hydrogen, alkyl or alkenyl; and R1 and R2 together can form a heterocycle; AND OF X and Y one is cyano and the other trifluoromethyl ARE HERBICIDES HAVING OUTSTANDING ACTIVITY AND SELECTIVITY.

Abstract translation: 式VI的新型6-硝基苯胺化合物，其中R1是氢，取代或未取代的烷基或芳基或环烷基; R2是氢，烷基或烯基; 并且R 1和R 2可以一起形成杂环; 并且X和Y一个是氰基，另外三氟甲基是具有超越活性和选择性的除草剂。

公开(公告)号：US3787435A

公开(公告)日：1974-01-22

申请号：US3787435D

申请日：1971-12-08

Applicant: BAYER AG

Inventor： SCHOLL HANS-JOACHIM ,  KLAUKE ERICH ,  GREWE FERDINAND ,  HAMMANN INGEBORG

IPC: A01N43/50 ,  A01N43/76 ,  A01N43/90 ,  C07D233/96 ,  C07D263/48 ,  C07D487/04 ,  C07D487/06 ,  C07D498/04 ,  C07D49/34 ,  C07D57/02

CPC classification number: C07D487/04 ,  C07D233/96 ,  C07D263/48

Abstract: AND R, R'', R" AND R''" EACH IS HYDROGEN OR VARIOUS OPTIONALL FIG-03 AND R, R'', R" AND R''" EACH IS HYDROGEN OR VARIOUS OPTIONALLY SUBSTITUTED HYDROCARBON OR HETEROCYCLIC RADICALS, SEVERAL OF THEM TOGETHER POSSIBLY FORMING A HETEROCYCLIC RING. THE INVENTION ALSO EXTENDS TO COMPOSITIONS CONTAINING, AND METHODS OF USING, THE NEW COMPOUNDS TO COMBAT FUNGI, INSECTS AND ACARIDS.

=C(-R'')-R"

IN WHICH Z IS OXYGEN, R-N= OR

Z=C
Z=C(-X-H)-NH(-R"'') + F3C-N=CF-CF=N-CF3 --->

4.5-BIS-(TRIFLUOROMETHYLIMINO)OXAZOLES OR DIAZOLES ARE PREPARED BY REACTING THE ENOL FORM OF AN AMIDE OR AN IMIDE OF A CARBOXYLIC ACID OR CARBONIC ACID, HAVING AT LEAST ONE HYDROGEN ATOM ON EACH OF AN OXYGEN AND NITROGEN OR TWO NITROGEN ATOMS VICINAL TO THE AMIDE CARBON ATOM, WITH PERFLUORO-2,4-DIAZAHEXA-2,4-DIENE IN THE PRESENCE OF A HYDROGEN FLUORIDE ACCEPTOR AT A TEMPERATURE OF ABOUT -50 TO 120*C., IN ACCORDANCE WITH THE FOLLOWING FORMULA

公开(公告)号：US3694444A

公开(公告)日：1972-09-26

申请号：US3694444D

申请日：1967-11-01

Applicant: BAYER AG

Inventor： KLAUKE ERICH ,  BIEN HANS-SAMUEL

IPC: C07D239/30 ,  C09B62/20 ,  C07D51/36

CPC classification number: C07D239/30 ,  C09B62/20 ,  C10M1/08 ,  C10M2215/22 ,  C10M2215/221 ,  C10M2215/225 ,  C10M2215/226 ,  C10M2215/30 ,  C10N2250/121

Abstract: A process of the preparation of fluoro substituted pyrimidines useful as lubricants, dyestuffs, pharamaceutical agents and pesticides which includes the isolated monofluoro-trichloro- and difluoro-dichloropyrimidines by reacting polyhalopyrimidines with hydrofluoric acid under increased temperature and pressure.

公开(公告)号：US3658992A

公开(公告)日：1972-04-25

申请号：US3658992D

申请日：1970-01-26

Applicant: BAYER AG

Inventor： KUHLE ENGELBERT ,  KLAUKE ERICH ,  DUESSELDORF BURSCHEID BEZIRK ,  SCHEINPFLUG HANS ,  FROHBERGER PAUL-ERNST

IPC: A01N47/04 ,  A01N9/16

CPC classification number: A01N47/04

Abstract: THE DISCLOSURE COVERS BROADLY N,N''-DI(ALKYL AND/OR ALKENYL)-N- OR -N,N''-DI-FLUORODICHLOROMETHYLMERCAPTOSULFAMIDES WHICH POSSESS FUNGICIDAL PROPERTIES AND WHICH MAY BE PREPARED BY CONVENTIONAL PROCEDURES.

公开(公告)号：US3592861A

公开(公告)日：1971-07-13

申请号：US3592861D

申请日：1969-06-03

Applicant: BAYER AG

Inventor： KLAUKE ERICH ,  KUHLE ENGELBERT

IPC: C07C205/11 ,  C07C205/12 ,  C07C79/12

CPC classification number: C07C205/11 ,  C07C201/12 ,  C07C205/12

Abstract: REACTING NITROBENZAL CHLORIDES, I.E. 2-(OPTIONALLY CHLORO)-3 OR 4-NITRO-BENZAL CHLORIDES OR 1-DICHLOROMETHYL2-(OPTIONALLY CHLORO)-3 OR 4-NITRO-BENZENSES WITH ANHYDROUS HYDROGEN FLUORIDE AT A TEMPERATURE OF ABOUT 0-150* C. AND A PRESSURE OF ABOUT 1-26 ATMOSPHERES ABSOLUTE, OPTIONALLY IN THE PRESENCE OF AN INERT ORGANIC LIQUID SOLVENT, TO FORM IN HIGH YIELD AND PURITY THE CORRESPONDING NITROBENZAL FLUORIDES, I.E. 2-(OPTIONALLY CHLORO)-3 OR 4NITRO-BENZAL FLUORIDES OF 1 - DIFLUOROMETHYL-2(OPTIONALLY CHLORO)-3 OR 4-NITRO-BENZENES, SOME OF WHICH ARE KNOWN, AND WHICH ARE INTERMEDIATES FOR THE PRODUCTION OF THE CORRESPONDING N-(DIFLUOROMETHYL-PHENYL)-N'',N''-DIMETHYL UREAS WHICH POSSESS PESTICIDAL, ESPECIALLY HERBICIDAL, PROPERTIES.

公开(公告)号：US3884931A

公开(公告)日：1975-05-20

申请号：US34480073

申请日：1973-03-26

Applicant: BAYER AG

Inventor： BUTTNER GERHARD ,  KLAUKE ERICH ,  FROHBERGER PAUL-ERNST ,  HAMMANN INGEBORG

IPC: A01N47/08 ,  A01N43/00 ,  C07D263/58 ,  C07D277/82 ,  C07D317/46 ,  C07D339/06 ,  C07D85/48

CPC classification number: C07D263/58 ,  C07D277/82 ,  C07D317/46 ,  C07D339/06

Abstract: 2-TRIFLUOROMETHYLIMINO-BENZO-HETEROCYCLIC COMPOUNDS OF THE GENERAL FORMULA

IN WHICH X is oxygen or sulfur, Y is oxygen, sulfur or the radical

R is a lower alkyl, cycloalkyl, aryl, aryl substituted by at least one of halogen, nitro, methyl and methoxy, alkylcarbalkoxy with up to 6 carbon atoms, alkysulfonyl, arylsulfonyl, dialkylamidosulfonyl, or -CO-R'', R'' is alkyl or alkoxy with up to 12 carbon atoms, aryl, amino, lower alkylamino, di-lower alkylamino, or arylamino, EACH Z independently is halogen, trifluoromethyl, nitro, lower alkyl, lower alkoxy, di-lower alkylamino, acyl with up to 6 carbon atoms, a sulfonic acid group, a sulfonic acid amide group, or a sulfonic acid amide group substituted by alkyl with up to 6 carbon atoms, and M IS AN INTEGER FROM 0 TO 4, WHERE POSSESS FUNGICIDAL, INSECTICIDAL AND ACARICIDAL PROPERTIES, AND A PROCESS FOR THEIR PREPARATION WHEREIN A COMPOUND OF THE GENERAL FORMULA

IS REACTED WITH PERFLUOROAZAPROPENE OF THE FORMULA

Abstract translation: 其中X为氧或硫，Y为氧，硫或基团R为低级烷基，环烷基，芳基，被卤素，硝基，甲基中的至少一个取代的芳基，其中R为低级烷基，环烷基，芳基，芳氧基， 具有至多6个碳原子的甲氧基，烷基烷氧基烷基磺酰基，芳基磺酰基，二烷基氨基磺酰基或-CO-R'，R'是具有至多12个碳原子的烷基或烷氧基，芳基，氨基，低级烷基氨基，二低级烷基氨基或 芳基氨基，每个Z独立地是卤素，三氟甲基，硝基，低级烷基，低级烷氧基，二低级烷基氨基，具有至多6个碳原子的酰基，磺酸基，磺酸酰胺基或被 具有多达6个碳原子的烷基，M是0至4的整数，在哪里具有杀真菌剂，杀虫剂和杀虫剂性质，以及其制备方法，其中一般化合物的化合物与式的全氟代苯甲酰化反应F2C = N -CF 3在非质子溶剂中 在氟化氢受体的存在下。