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公开(公告)号：US09359362B2
公开(公告)日：2016-06-07
申请号：US14047458
申请日：2013-10-07
发明人： Franz Von Nussbaum , Dagmar Karthaus , Sonja Anlauf , Martina Delbeck , Volkhart Min-Jian Li , Daniel Meibom , Klemens Lustig
IPC分类号： A01N43/90 , A61K31/519 , C07D487/00 , C07D487/04 , A61K45/06 , C07D487/14
CPC分类号： C07D487/04 , A61K31/519 , A61K45/06 , C07D487/14
摘要： The present invention relates to novel heterocyclically fused diaryldihydropyrimidine derivatives, to processes for their preparation, to their use alone or in combination for the treatment and/or prevention of diseases and also to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of disorders of the lung and the cardiovascular system.
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公开(公告)号：US09174997B2
公开(公告)日：2015-11-03
申请号：US14522510
申请日：2014-10-23
发明人： Franz Von Nussbaum , Dagmar Karthaus , Sonja Anlauf , Martina Delbeck , Volkhart Min-Jian Li , Daniel Meibom , Klemens Lustig , Jens Schamberger
IPC分类号： A61K31/513 , C07D487/04 , C07D239/22 , A61K31/519 , A61K31/5377 , A61K31/541 , A61K45/06 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/06 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/06 , C07D413/12 , C07D417/12
CPC分类号： C07D487/04 , A61K31/513 , A61K31/519 , A61K31/5377 , A61K31/541 , A61K45/06 , C07D239/22 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/06 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/06 , C07D413/12 , C07D417/12
摘要： The present invention relates to novel 4-(4-cyano-2-thioaryl)dihydropyrimidin-2-one derivatives, to processes for their preparation, to their use alone or in combination for the treatment and/or prevention of diseases and also to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of disorders of the lung and the cardiovascular system.
摘要翻译： 本发明涉及新的4-（4-氰基-2-硫代芳基）二氢嘧啶-2-酮衍生物，其制备方法，单独使用或组合用于治疗和/或预防疾病，以及它们 用于制备治疗和/或预防疾病的药物，特别是用于治疗和/或预防肺和心血管系统疾病。
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