公开(公告)号：US20130237551A1

公开(公告)日：2013-09-12

申请号：US13851373

申请日：2013-03-27

申请人： Bayer Intellectual Property GmbH

发明人： Markus FOLLMANN ,  Johannes-Peter STASCH ,  Gorden REDLICH ,  Jens ACKERSTAFF ,  Nils GRIEBENOW ,  Walter KROH ,  Andreas KNORR ,  Eva-Maria BECKER ,  Frank WUNDER ,  Volkhart Min-Jian LI ,  Elke HARTMANN ,  Joachim MITTENDORF ,  Karl-Heinz SCHLEMMER ,  Rolf JAUTELAT ,  Donald BIERER

IPC分类号： A61K31/506 ,  A61K45/06

CPC分类号： A61K31/506 ,  A61K45/06 ,  C07C57/145 ,  C07C309/04 ,  C07C309/05 ,  C07D471/04

摘要： The present application relates to novel substituted 5-fluoro-1H-pyrazolopyridines, to processes for their preparation, to their use alone or in combinations for the treatment and/or prophylaxis of diseases, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular disorders.

公开(公告)号：US20150080414A1

公开(公告)日：2015-03-19

申请号：US14552122

申请日：2014-11-24

申请人： BAYER INTELLECTUAL PROPERTY GmbH

发明人： Markus FOLLMANN ,  Johannes-Peter STASCH ,  Gorden REDLICH ,  Jens ACKERSTAFF ,  Nils GRIEBENOW ,  Walter KROH ,  Andreas KNORR ,  Eva-Maria BECKER ,  Frank WUNDER ,  Volkhart Min-Jian LI ,  Elke HARTMANN ,  Joachim MITTENDORF ,  Karl-Heinz SCHLEMMER ,  Rolf JAUTELAT ,  Donald BIERER

IPC分类号： C07D471/04 ,  A61K45/06 ,  A61K31/506

CPC分类号： A61K31/506 ,  A61K45/06 ,  C07C57/145 ,  C07C309/04 ,  C07C309/05 ,  C07D471/04

摘要： The present application relates to novel substituted 5-fluoro-1H-pyrazolopyridines, to processes for their preparation, to their use alone or in combinations for the treatment and/or prophylaxis of diseases, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular disorders.

摘要翻译： 本申请涉及新的取代的5-氟-1H-吡唑并吡啶，其制备方法，单独使用或组合用于治疗和/或预防疾病，以及它们用于制备用于治疗和/ 或预防疾病，特别是用于治疗和/或预防心血管疾病。