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公开(公告)号:US20230416249A1
公开(公告)日:2023-12-28
申请号:US18315472
申请日:2023-05-10
申请人: Bayer Aktiengesellschaft , Bayer Pharma Aktiengesellschaft , The Broad Institute, Inc. , Dana-Farber Cancer Institute, Inc.
发明人: Stephan SIEGEL , Franziska SIEGEL , Volker SCHULZE , Markus BERGER , Keith GRAHAM , Ulrich KLAR , Jeremie Xavier G. MORTIER , Detlev SÜLZLE , Ulf BÖMER , Daniel KORR , Jens SCHRÖDER , Matthew MEYERSON , Heidi GREULICH , Bethany KAPLAN
IPC分类号: C07D471/04 , A61P35/00 , G01N33/574
CPC分类号: C07D471/04 , A61P35/00 , G01N33/57492 , G01N2333/71
摘要: Compounds of formula (I)
processes for their production and their use as pharmaceuticals.-
公开(公告)号:US20210221798A1
公开(公告)日:2021-07-22
申请号:US17218907
申请日:2021-03-31
发明人: Markus BERGER , Jessica LOHRKE , Christoph-Stephan HILGER , Gregor JOST , Thomas FRENZEL , Olaf PANKNIN , Hubertus PIETSCH
IPC分类号: C07D403/14 , A61K49/10 , C07D257/02
摘要: The present invention relates to a new class of high relaxivity extracellular gadolinium chelate complexes, to methods of preparing said compounds, and to the use of said compounds as MRI contrast agents.
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公开(公告)号:US20200283420A1
公开(公告)日:2020-09-10
申请号:US16463076
申请日:2017-11-24
发明人: Markus BERGER , Jessica LOHRKE , Christoph-Stephan HILGER , Gregor JOST , Thomas FRENZEL , Olaf PANKNIN , Hubertus PIETSCH
IPC分类号: C07D403/14 , A61K49/10 , C07D257/02
摘要: The present invention relates to a new class of high relaxivity extracellular gadolinium chelate complexes, to methods of preparing said compounds, and to the use of said compounds as MRI contrast agents.
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公开(公告)号:US20190218196A1
公开(公告)日:2019-07-18
申请号:US15779691
申请日:2016-11-30
发明人: Markus BERGER , Jan HÜBNER , Antonius TER LAAK , Matyas GORJANACZ , Amaury Ernesto FERNANDEZ-MONTALVAN , Vincent RODESCHINI , Didier ROCHE
IPC分类号: C07D307/52 , C07D405/12 , C07D487/10 , A61K45/06 , A61K31/341 , A61K31/4025 , A61K31/5377 , A61K31/496 , A61K31/4178 , A61K31/4196 , A61K31/4525 , A61K31/397 , A61K31/403
CPC分类号: C07D307/52 , A61K31/341 , A61K31/397 , A61K31/4025 , A61K31/403 , A61K31/4178 , A61K31/4196 , A61K31/4525 , A61K31/496 , A61K31/5377 , A61K45/06 , C07D307/38 , C07D405/12 , C07D487/10
摘要: The invention relates to furane derivatives of formula (I) as inhibitors of ATAD2, a process for their preparation and use thereof.
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