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公开(公告)号：US20210047398A1
公开(公告)日：2021-02-18
申请号：US16867183
申请日：2020-05-05
发明人： Atul Chopra , David D. Moore
摘要： Embodiments of the disclosure concern methods and compositions that relate to increasing or decreasing the weight (including, for example, by increasing or decreasing the adipose mass) in individuals in need thereof. Such methods and compositions, in particular embodiments, concern providing an effective amount of the hormone asprosin to increase adipose mass in an individual with insufficient adipose mass and providing an antibody or inhibitor of asprosin in an individual with obesity or diabetes, for example, to reduce adipose mass.
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公开(公告)号：US20190144536A1
公开(公告)日：2019-05-16
申请号：US16092653
申请日：2017-04-13
发明人： Atul Chopra , David D. Moore
摘要： Embodiments of the disclosure concern methods and compositions that relate to increasing or decreasing the weight (including, for example, by increasing or decreasing the adipose mass) in individuals in need thereof. Such methods and compositions, in particular embodiments, concern providing an effective amount of the hormone asprosin to increase adipose mass in an individual with insufficient adipose mass and providing an antibody or inhibitor of asprosin in an individual with obesity or diabetes, for example, to reduce adipose mass.
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3.发明申请公开(公告)号：US20160289289A1
公开(公告)日：2016-10-06
申请号：US15038435
申请日：2014-11-24
发明人： Atul Chopra , David D. Moore
IPC分类号： C07K14/575 , C07K16/26
CPC分类号： A61K38/22 , C07K14/575 , C07K14/78 , C07K16/26 , C07K2317/76
摘要： Embodiments of the disclosure concern methods and compositions that relate to increasing or decreasing the weight (including, for example, by increasing or decreasing the adipose mass) in individuals in need thereof. Such methods and compositions, in particular embodiments, concern providing an effective amount of the hormone asprosin to increase adipose mass in an individual with insufficient adipose mass and providing an antibody or inhibitor of asprosin in an individual with obesity or diabetes, for example, to reduce adipose mass.
摘要翻译： 本公开的实施方案涉及涉及在有需要的个体中增加或减少体重（包括例如通过增加或减少脂肪质量）的方法和组合物。 在特定实施方案中，这些方法和组合物涉及提供有效量的激素阿司匹林，以增加脂肪量不足的个体中的脂肪质量，并在个体中提供肥胖或糖尿病的抗体或抑制剂，例如减少 脂肪质量
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4.发明申请公开(公告)号：US20220211816A1
公开(公告)日：2022-07-07
申请号：US17654968
申请日：2022-03-15
发明人： Atul Chopra , David D. Moore
IPC分类号： A61K38/22 , C07K14/78 , C07K14/575
摘要： Embodiments of the disclosure concern methods and compositions that relate to increasing or decreasing the weight (including, for example, by increasing or decreasing the adipose mass) in individuals in need thereof. Such methods and compositions, in particular embodiments, concern providing an effective amount of the hormone asprosin to increase adipose mass in an individual with insufficient adipose mass and providing an antibody or inhibitor of asprosin in an individual with obesity or diabetes, for example, to reduce adipose mass.
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5.发明申请公开(公告)号：US20190282664A1
公开(公告)日：2019-09-19
申请号：US16424321
申请日：2019-05-28
发明人： Atul Chopra , David D. Moore
IPC分类号： A61K38/22 , C07K14/575 , C07K14/78
摘要： Embodiments of the disclosure concern methods and compositions that relate to increasing or decreasing the weight (including, for example, by increasing or decreasing the adipose mass) in individuals in need thereof. Such methods and compositions, in particular embodiments, concern providing an effective amount of the hormone asprosin to increase adipose mass in an individual with insufficient adipose mass and providing an antibody or inhibitor of asprosin in an individual with obesity or diabetes, for example, to reduce adipose mass.
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公开(公告)号：US10328127B2
公开(公告)日：2019-06-25
申请号：US15038435
申请日：2014-11-24
发明人： Atul Chopra , David D. Moore
IPC分类号： A61K38/17 , A61K38/22 , C07K14/78 , C07K14/575 , C07K16/26
摘要： Embodiments of the disclosure concern methods and compositions that relate to increasing or decreasing the weight (including, for example, by increasing or decreasing the adipose mass) in individuals in need thereof. Such methods and compositions, in particular embodiments, concern providing an effective amount of the hormone asprosin to increase adipose mass in an individual with insufficient adipose mass and providing an antibody or inhibitor of asprosin in an individual with obesity or diabetes, for example, to reduce adipose mass.
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