公开(公告)号：US12099177B2

公开(公告)日：2024-09-24

申请号：US17913958

申请日：2020-04-08

Applicant: BGI SHENZHEN

Inventor： Qing Xie ,  Wei-Mao Wang ,  Wen-Wei Zhang ,  Mengzhe Shen

IPC: G02B21/36 ,  G03H1/04 ,  G03H1/00

CPC classification number: G02B21/361 ,  G02B21/367 ,  G03H1/0443 ,  G03H2001/005

Abstract: A lens-free microscopic imaging system (11), which is used to image microbeads (15) with pattern codes, includes an illumination system (11a) and an imaging system (11b). The illumination system (11a) includes an illumination light source (111) and an excitation light source (112). The imaging system (11b) includes an image sensor (113). The illumination light source (111) is used to emit illumination light to irradiate the microbeads (15), causing the irradiated microbeads (15) to be imaged on the image sensor. The excitation light source (112) is used to emit excitation light to excite the microbeads (15) to generate specific signals. The image sensor (113) is used to collect the images of the microbeads (15) and the specific signals to generate images. The imaging system (11) does not require a lens system. The present disclosure improves a detection efficiency of the microbeads (15).