公开(公告)号：US20210264596A1

公开(公告)日：2021-08-26

申请号：US17256316

申请日：2019-06-28

Applicant: BIOCELLVIA

Inventor： Yvon JULE ,  Florent TOMI ,  Jean-Claude GILHODES

IPC: G06T7/00 ,  G06T7/62 ,  G06T11/20 ,  G16H30/40 ,  G16H50/50 ,  G16H50/30 ,  G16H50/70 ,  G16H15/00

Abstract: A method for producing a multiparameter graphic indicator relating to a remodelling of the human or animal bronchial epithelium from a digital representation of a histological section of a lung comprising one or more components, each of which describes a wall enclosing a lumen. Such a method makes it possible, in particular, to estimate one or more quantities of interest relating to one or more components in order to produce a graphical representation describing the quantity or quantities of interest so as to assist with diagnosing a disease or analyzing the effectiveness of a molecule for therapeutic purposes. The method is implemented by a processing unit of an electronic object of a histological analysis system.

公开(公告)号：US20230117179A1

公开(公告)日：2023-04-20

申请号：US17907035

申请日：2020-03-24

Applicant: Biocellvia

Inventor： Yvon JULE ,  Florent TOMI ,  Damien BARBES ,  Karine BERTOTTI

IPC: G06T7/00 ,  C12N5/071 ,  G01N1/30

Abstract: The invention relates to a method for producing variables of interest relating to human or animal hepatic tissue from a digital representation of a histological section. Such a method is intended to be implemented by a unit for processing a medical imaging system to automatically and quickly provide diagnosis assistance, in particular for NASH, to healthcare personnel. The variables of interest respectively describe a level of steatosis of the hepatic tissue, a level of fibrosis in the portal, central and perisinusoidal areas of the hepatic lobule and a level of inflammation of the hepatic tissue. A method according to the invention further provides for producing a multiparametric indicator in the form of graphical representations arranged to be displayed by an output human-machine interface of the medical imaging system.

公开(公告)号：US20210174508A1

公开(公告)日：2021-06-10

申请号：US17256143

申请日：2019-06-28

Applicant: Biocellvia

Inventor： Yvon JULE ,  Florent TOMI ,  Jean-Claude GILHODES

IPC: G06T7/00 ,  G06T7/60

Abstract: The invention concerns a method for producing a multiparameter graphic indicator relating to a remodelling of human or animal pulmonary alveoli from a digital representation of a histological section of a lung comprising one or more components each of which describes a wall enclosing a lumen. The method can estimate one or more quantities of interest relating to one or more components in order to produce a graphic representation describing the quantity or quantities of interest in order to provide an aid for diagnosis of a disease or for analysis of the therapeutic effectiveness of molecules. The method is implemented by a processing unit of an electronic object of the histological analysis system.