公开(公告)号：US11747351B2

公开(公告)日：2023-09-05

申请号：US16848445

申请日：2020-04-14

Applicant: BIOVERATIV THERAPEUTICS INC.

Inventor： Jurg Sommer ,  Haiyan Jiang ,  Xin Zhang ,  Buyue Yang ,  Glenn Pierce

IPC: G01N33/86 ,  C12N9/64

CPC classification number: G01N33/86 ,  C12N9/644 ,  G01N2333/755 ,  G01N2333/9645 ,  G01N2333/974

Abstract: The present invention provides methods of dosing Factor VIII or Factor IX chimeric and hybrid polypeptides. The present invention further provides high-sensitivity methods of quantifying an amount of activated FIX protein in a test sample.