公开(公告)号：US20190003933A1

公开(公告)日：2019-01-03

申请号：US16022003

申请日：2018-06-28

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： JEFF GRAY ,  JOSHUA CLARK ,  SAMUEL RAYBIN ,  RYAN V. WALES

IPC: G01N1/22 ,  G01N1/14

Abstract: Devices for physically separating biological samples and methods for separating biological samples are disclosed. An example device may include a vessel for holding a biological sample. The biological sample may include a plurality of cells and a fluid. A filter membrane may be disposed within the vessel and positioned adjacent to an end region of the vessel. An auger member may be disposed within the vessel. The auger member may be designed to drive cells within the biological sample into contact with the filter membrane.

公开(公告)号：US20190003935A1

公开(公告)日：2019-01-03

申请号：US16019078

申请日：2018-06-26

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： JOSHUA CLARK ,  GENE T. STORBECK ,  SHANNON SMITH KENWOOD ,  CHRISTOPHER A. BENNING ,  SEAN CURRAN ,  SARAH JEAN HEIGHTON

IPC: G01N1/31 ,  A61B10/02 ,  B01L3/00 ,  G01N1/40 ,  G01N33/50

Abstract: A cell filtration assembly adapted to capture cells from a biological sample during centrifugation includes a filter support member including a sample well and a filter membrane that spans the sample well. In some cases, the filter support member and/or the filter membrane may be adapted to be sectioned. In some cases, a protective element may be disposed over at least a portion of the filter support member in order to protect the filter support member from tissue processing reagents during processing of the cells captured from the biological sample.

公开(公告)号：US20190001347A1

公开(公告)日：2019-01-03

申请号：US16018897

申请日：2018-06-26

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： SHANNON SMITH KENWOOD ,  SARAH JEAN HEIGHTON ,  JOSHUA CLARK ,  DAN BACON

IPC: B04B5/04 ,  B01D21/26 ,  B01D61/14 ,  B01D61/18

Abstract: Filtration devices and methods for collecting, filtering, and/or processing biological samples are disclosed. An example filtration device may include a funnel member having a first end region and a second end region. A flange may be coupled to the first end region. A filter support portion may be coupled to the second end region. The filter support portion may include a base, a filter membrane coupled to the base, and a securing member for securing the filter membrane to the base.

公开(公告)号：US20190001323A1

公开(公告)日：2019-01-03

申请号：US16022108

申请日：2018-06-28

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： SARAH JEAN HEIGHTON ,  SHANNON SMITH KENWOOD ,  JOSHUA CLARK

IPC: B01L3/00 ,  B01D63/08 ,  B01D61/18

Abstract: A cell filtration assembly adapted to capture cells from a biological sample during centrifugation includes a centrifugation tube, a cell collection device adapted to be secured within a tapered end of the centrifugation tube and a funnel structure adapted to direct fluid into the cell collection device. The cell collection device includes a rectilinear structure that is adapted to permit fluid to flow through the rectilinear structure and a cell capture surface that is secured relative to the rectilinear structure. The cell collection device may be sectioned in either a horizontal or vertical orientation.