公开(公告)号：US20180264177A1

公开(公告)日：2018-09-20

申请号：US15981381

申请日：2018-05-16

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： JOHN HINGSTON ,  GARY JORDAN ,  WILLIAM BERTOLINO ,  PAUL K. NORTON ,  JASON WEINER

IPC: A61L27/58 ,  A61L31/10 ,  A61L31/14

CPC classification number: A61L27/58 ,  A61L31/10 ,  A61L31/148 ,  A61L2420/02 ,  A61L2420/08 ,  A61L2430/36

Abstract: A stent, the stent including a first coating composition disposed on at least a portion of the outer surface of the stent, the first coating composition having at least one bioadhesive and a second coating composition disposed over the first coating composition, the second coating composition having at least one biodegradable polymer, and methods of making and using the same.

公开(公告)号：US20230149190A1

公开(公告)日：2023-05-18

申请号：US18156699

申请日：2023-01-19

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： WILLIAM BERTOLINO ,  LAURA ELIZABETH FIRSTENBERG ,  CLAIRE M. MCLEOD ,  ANDREA LAI ,  SANDRA LAM ,  SHANNON TAYLOR

IPC: A61F2/90 ,  A61F2/848 ,  A61F2/91 ,  A61F2/86

CPC classification number: A61F2/90 ,  A61F2/848 ,  A61F2/91 ,  A61F2/86 ,  B29C65/48

Abstract: An endoprosthesis has an expanded state and a contracted state, the endoprosthesis includes a stent having an inner surface defining a lumen, having an outer surface, and defining a plurality of apertures through the outer surface, wherein the apertures are arranged in a micropattern; and a coating (e.g., polymeric coating) attached to the outer surface of the stent. The coating includes a base and a tissue engagement portion including a second surface facing outwardly from the stent, the tissue engagement portion including a structure that defines a plurality of holes extending inwardly from the second surface toward the base. The holes are arranged in a micropattern. When the endoprosthesis is expanded to the expanded state in a lumen defined by a vessel wall, the structure applies a force that may reduce stent migration by creating an interlock between the vessel wall and the endoprosthesis.

公开(公告)号：US20200146803A1

公开(公告)日：2020-05-14

申请号：US16738326

申请日：2020-01-09

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： WILLIAM BERTOLINO ,  LAURA ELIZABETH FIRSTENBERG ,  CLAIRE M. MCLEOD ,  ANDREA LAI ,  SANDRA LAM ,  SHANNON TAYLOR

IPC: A61F2/04 ,  A61F2/848 ,  A61F2/90 ,  B29C65/48 ,  B29C65/00 ,  A61F2/07 ,  B29C45/37

Abstract: An endoprosthesis has an expanded state and a contracted state, the endoprosthesis includes a stent having an inner surface defining a lumen, having an outer surface, and defining a plurality of apertures through the outer surface, wherein the apertures are arranged in a micropattern; and a coating (e.g., polymeric coating) attached to the outer surface of the stent. The coating includes a base and a tissue engagement portion including a second surface facing outwardly from the stent, the tissue engagement portion including a structure that defines a plurality of holes extending inwardly from the second surface toward the base. The holes are arranged in a micropattern. When the endoprosthesis is expanded to the expanded state in a lumen defined by a vessel wall, the structure applies a force that may reduce stent migration by creating an interlock between the vessel wall and the endoprosthesis.

公开(公告)号：US20170065398A1

公开(公告)日：2017-03-09

申请号：US15355529

申请日：2016-11-18

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： WILLIAM BERTOLINO ,  LAURA ELIZABETH FIRSTENBERG ,  CLAIRE M. MCLEOD ,  ANDREA LAI ,  SANDRA LAM ,  SHANNON TAYLOR

IPC: A61F2/04 ,  B29C65/00 ,  B29C65/48 ,  B29C45/37 ,  A61F2/90 ,  A61F2/848

Abstract: An endoprosthesis has an expanded state and a contracted state, the endoprosthesis includes a stent having an inner surface defining a lumen, having an outer surface, and defining a plurality of apertures through the outer surface, wherein the apertures are arranged in a micropattern; and a coating (e.g., polymeric coating) attached to the outer surface of the stent. The coating includes a base and a tissue engagement portion including a second surface facing outwardly from the stent, the tissue engagement portion including a structure that defines a plurality of holes extending inwardly from the second surface toward the base. The holes are arranged in a micropattern. When the endoprosthesis is expanded to the expanded state in a lumen defined by a vessel wall, the structure applies a force that may reduce stent migration by creating an interlock between the vessel wall and the endoprosthesis.

Abstract translation: 内假体具有扩张状态和收缩状态，内假体包括具有限定内腔的内表面的支架，具有外表面，并且通过外表面限定多个孔，其中所述孔布置在微图案中; 以及附着到支架的外表面的涂层（例如，聚合物涂层）。 涂层包括基部和组织接合部分，其包括从支架向外的第二表面，所述组织接合部分包括限定从第二表面朝向基部向内延伸的多个孔的结构。 孔布置在微图案中。 当在由血管壁限定的内腔中将内假体扩张到扩张状态时，该结构施加可以通过在血管壁和内用假体之间产生互锁来减少支架迁移的力。