公开(公告)号：US20190275180A1

公开(公告)日：2019-09-12

申请号：US16363193

申请日：2019-03-25

Applicant: BRACCO IMAGING S.P.A.

Inventor： Mathilde H. LERCHE ,  Pernille Rose JENSEN ,  Magnus KARLSSON ,  Roberta NAPOLITANO ,  Claudia CABELLA ,  Luigi MIRAGOLI ,  Sonia COLOMBO SERRA ,  Fabio TEDOLDI

IPC: A61K51/04 ,  A61B5/00 ,  A61K49/10 ,  C07C69/007 ,  C07B59/00 ,  A61B5/055

Abstract: 1-13C-1,1-Bis(acetoxy(methyl))-2,2′-cyclopropane of formula (I): The compound can be hyperpolarized and used as a contrast agent in 13C Magnetic Resonance diagnostic technique (13C-MR) for the diagnosis of tumor.